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Original Research

Six-month results from a Phase III randomized trial of fixed-combination brinzolamide 1% + brimonidine 0.2% versus brinzolamide or brimonidine monotherapy in glaucoma or ocular hypertension

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Pages 1053-1060 | Published online: 06 Jun 2013

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Read on this site (6)

Anastasios G. Konstas, Leopold Schmetterer, Vital P. Costa, Gábor Holló, Andreas Katsanos, Philippe Denis, Luciano Quaranta, Murat Irkec, Miguel A. Castejón, Miguel A. Teus & Alan L. Robin. (2020) Current and emerging fixed combination therapies in glaucoma: a safety and tolerability review. Expert Opinion on Drug Safety 19:11, pages 1445-1460.
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Lindsay Machen, Reza Razeghinejad & Jonathan S. Myers. (2020) Fixed-combination topical anti-hypertensive ophthalmic agents. Expert Opinion on Pharmacotherapy 21:10, pages 1269-1282.
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S Fabián Lerner, Francesco Oddone, Da-Wen Lu, Ana Sanseau, Merce Guarro, Antonia Ridolfi & Douglas Hubatsch. (2019) Maximum Medical Therapy: Brinzolamide/Brimonidine And Travoprost/Timolol Fixed-Dose Combinations In Glaucoma And Ocular Hypertension. Clinical Ophthalmology 13, pages 2411-2419.
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Sourabh Sharma, Sameer Trikha, Shamira A Perera & Tin Aung. (2015) Clinical effectiveness of brinzolamide 1%–brimonidine 0.2% fixed combination for primary open-angle glaucoma and ocular hypertension. Clinical Ophthalmology 9, pages 2201-2207.
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Sky K Chew, Simon E Skalicky & Ivan Goldberg. (2014) Brinzolamide plus brimonidine for the treatment of glaucoma: an update. Expert Opinion on Pharmacotherapy 15:16, pages 2461-2471.
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Articles from other publishers (17)

Ryota Aoki, Etsuko Terao, Saki Dote, Miku Shiraishi, Satomi Oogi, Kanae Ueda, Yui Kimura, Yuki Nagata & Shunsuke Nakakura. (2022) Efficacy and safety of a fixed combination of 1% brinzolamide and 0.1% brimonidine as treatment for glaucoma: a retrospective study focusing on the number of ingredients. BMJ Open Ophthalmology 7:1, pages e001200.
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Sapna Sinha, Wesam Shamseldin Shalaby, Wendy W. Liu, Reza Razeghinejad & L. Jay Katz. 2022. Comprehensive Pharmacology. Comprehensive Pharmacology 612 661 .
Yara P. Catoira-Boyle, Darrell WuDunn, Louis B. Cantor, John T. Lind, Elizabeth Ann Martin & Steve L. Gerber. 2022. Albert and Jakobiec's Principles and Practice of Ophthalmology. Albert and Jakobiec's Principles and Practice of Ophthalmology 2331 2399 .
Jin A Kim & Heeyoung Lee. (2021) Effectiveness and Safety Verification of Brinzolamide Combination Therapy on Primary Open-angle Glaucoma or Ocular Hypertension: A Systematic Review and Meta-analysis Study. Korean Journal of Clinical Pharmacy 31:3, pages 205-215.
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P S Rastogi, Kanupriya Jain, Ashish Chander & Munavvar Ansari. (2021) A comparative study of topical fixed dose combination of brimonidine (0.2%) plus brinzolamide (1%) versus brimonidine (0.2%) plus timolol (0.5%) in patients of primary open angle glaucoma. Indian Journal of Clinical and Experimental Ophthalmology 7:1, pages 112-117.
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Sang Woo Park, Joon Mo Kim, Ji Woong Lee, Joy Maglambayan, Susan Simonyi & Ki Ho Park. (2021) Efficacy and safety of fixed-combination brimonidine tartrate/timolol maleate in primary open-angle glaucoma, including normal-tension glaucoma. Japanese Journal of Ophthalmology 65:2, pages 295-305.
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In Ki Park, Seon Ha Bae, Kyoung Woo Kim & Yeoun Sook Chun. (2020) Clinical Characteristics of Allergy to a Brinzolamide 1.0%/Brimonidine 0.2% Fixed Combination in Korean Glaucoma Patients. Journal of the Korean Ophthalmological Society 61:9, pages 1065-1071.
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Péter Kóthy & Gábor Holló. (2019) Real-life experience of using brinzolamide/brimonidine fixed drop combination in a tertiary glaucoma centre. International Ophthalmology 40:2, pages 377-383.
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Yara P. Catoira-Boyle, Darrell WuDunn, Louis B. Cantor, John T. Lind, Elizabeth Ann Martin & Steve L. Gerber. 2020. Albert and Jakobiec's Principles and Practice of Ophthalmology. Albert and Jakobiec's Principles and Practice of Ophthalmology 1 69 .
Yuanzhi Liu, Junyi Zhao, Xiaoyan Zhong, Qiming Wei & Yilan Huang. (2019) Efficacy and Safety of Brinzolamide as Add-On to Prostaglandin Analogues or β-Blocker for Glaucoma and Ocular Hypertension: A Systematic Review and Meta-Analysis. Frontiers in Pharmacology 10.
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Reza Moosavi & Ejaz Ansari. (2018) Brinzolamide/Brimonidine Fixed Combination: Simplifying Glaucoma Treatment Regimens. Ophthalmology and Therapy 7:2, pages 397-403.
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In Tae KimJeong Hun BaeJoon Mo Kim. (2018) Clinical Effectiveness of a Brinzolamide 1%-Brimonidine 0.2% Fixed Combination for Normal Tension Glaucoma in South Koreans. Journal of the Korean Ophthalmological Society 59:6, pages 561.
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R D Fechtner, J S Myers, D A Hubatsch, D L Budenz & H B DuBiner. (2016) Ocular hypotensive effect of fixed-combination brinzolamide/brimonidine adjunctive to a prostaglandin analog: a randomized clinical trial. Eye 30:10, pages 1343-1350.
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Robert M. Feldman, Gregory Katz, Matthew McMenemy, Douglas A. Hubatsch & Tony Realini. (2016) A Randomized Trial of Fixed-Dose Combination Brinzolamide 1%/Brimonidine 0.2% as Adjunctive Therapy to Travoprost 0.004%. American Journal of Ophthalmology 165, pages 188-197.
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Sarah L. Greig & Emma D. Deeks. (2015) Brinzolamide/Brimonidine: A Review of Its Use in Patients with Open-Angle Glaucoma or Ocular Hypertension. Drugs & Aging 32:3, pages 251-260.
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Tin Aung, Guna Laganovska, Tania Josefina Hernandez Paredes, James D. Branch, Alexis Tsorbatzoglou & Ivan Goldberg. (2014) Twice-Daily Brinzolamide/Brimonidine Fixed Combination versus Brinzolamide or Brimonidine in Open-Angle Glaucoma or Ocular Hypertension. Ophthalmology 121:12, pages 2348-2355.
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Stefano A. Gandolfi, John Lim, Ana Cristina Sanseau, Juan Camilo Parra Restrepo & Thomas Hamacher. (2014) Randomized Trial of Brinzolamide/Brimonidine Versus Brinzolamide Plus Brimonidine for Open-Angle Glaucoma or Ocular Hypertension. Advances in Therapy 31:12, pages 1213-1227.
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