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Original Research

Folate status in type 2 diabetic patients with and without retinopathy

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Pages 1437-1442 | Published online: 07 Aug 2015

Keep up to date with the latest research on this topic with citation updates for this article.

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Omid Asbaghi, Damoon Ashtary-Larky, Reza Bagheri, Behzad Nazarian, Hadi Pourmirzaei Olyaei, Mahnaz Rezaei Kelishadi, Michael Nordvall, Alexei Wong, Frédéric Dutheil & Amirmansour Alavi Naeini. (2022) Beneficial effects of folic acid supplementation on lipid markers in adults: A GRADE-assessed systematic review and dose-response meta-analysis of data from 21,787 participants in 34 randomized controlled trials. Critical Reviews in Food Science and Nutrition 62:30, pages 8435-8453.
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Michael Wakeman & David T Archer. (2020) Metformin and Micronutrient Status in Type 2 Diabetes: Does Polypharmacy Involving Acid-Suppressing Medications Affect Vitamin B12 Levels?. Diabetes, Metabolic Syndrome and Obesity 13, pages 2093-2108.
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Michele Malaguarnera, Saverio Latteri, Gaetano Bertino, Roberto Madeddu, Vito Emanuele Catania, Giuseppe Currò, Antonio Maria Borzì, Filippo Drago & Giulia Malaguarnera. (2018) D-dimer plasmatic levels as a marker for diagnosis and prognosis of hepatocellular carcinoma patients with portal vein thrombosis. Clinical and Experimental Gastroenterology 11, pages 373-380.
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Chunyang Cai, Chunren Meng, Shuai He, Chufeng Gu, Thashi Lhamo, Deji Draga, Dawei Luo & Qinghua Qiu. (2022) DNA methylation in diabetic retinopathy: pathogenetic role and potential therapeutic targets. Cell & Bioscience 12:1.
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Varis Ruamviboonsuk & Andrzej Grzybowski. (2022) The Roles of Vitamins in Diabetic Retinopathy: A Narrative Review. Journal of Clinical Medicine 11:21, pages 6490.
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Agostino Milluzzo, Martina Barchitta, Andrea Maugeri, Roberta Magnano San Lio, Giuliana Favara, Maria Grazia Mazzone, Laura Sciacca & Antonella Agodi. (2022) Do Nutrients and Nutraceuticals Play a Role in Diabetic Retinopathy? A Systematic Review. Nutrients 14:20, pages 4430.
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Hexin Su, Yacong Bo, Xiaoan Zhang, Junxi Zhang, Zhan Gao & Zengli Yu. (2022) Associations of folate intake with all-cause and cause-specific mortality among individuals with diabetes. Frontiers in Nutrition 9.
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Guoheng Zhang, Xiaojia Sun, Tianhao Yuan, Changmei Guo, Ziyi Zhou, Ling Wang & Guorui Dou. (2022) Certain Dietary Nutrients Reduce the Risk of Eye Affliction/Retinopathy in Individuals with Diabetes: National Health and Nutrition Examination Survey, 2003–2018. International Journal of Environmental Research and Public Health 19:19, pages 12173.
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Wei-Ming Luo, Zhi-Peng Zhang, Wei Zhang, Jing-Yang Su, Xiao-Qian Gao, Xu Liu, Wan-Ying Wang, Chang-Tao Jiang & Zhong-Ze Fang. (2022) The Association of Homocysteine and Diabetic Retinopathy in Homocysteine Cycle in Chinese Patients With Type 2 Diabetes. Frontiers in Endocrinology 13.
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Yujie Liu, Tingting Geng, Zhenzhen Wan, Qi Lu, Xuena Zhang, Zixin Qiu, Lin Li, Kai Zhu, Liegang Liu, An Pan & Gang Liu. (2022) Associations of Serum Folate and Vitamin B 12 Levels With Cardiovascular Disease Mortality Among Patients With Type 2 Diabetes . JAMA Network Open 5:1, pages e2146124.
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Martina Tomić, Romano Vrabec, Spomenka Ljubić, Tomislav Bulum & Dario Rahelić. (2022) Plasma homocysteine is associated with nonproliferative retinopathy in patients with type 2 diabetes without renal disease. Diabetes & Metabolic Syndrome: Clinical Research & Reviews 16:1, pages 102355.
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Lei Hong, Yingjie Zha, Chen Wang, Shigang Qiao & Jianzhong An. (2021) Folic Acid Alleviates High Glucose and Fat-Induced Pyroptosis via Inhibition of the Hippo Signal Pathway on H9C2 Cells. Frontiers in Molecular Biosciences 8.
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Uwe Gröber. (2021) Metformin – bei Typ-2-Diabetes das Mittel der ersten Wahl?!. Zeitschrift für Orthomolekulare Medizin 19:03, pages 7-14.
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Manon D. Owen, Bernadette C. Baker, Eleanor M. Scott & Karen Forbes. (2021) Interaction between Metformin, Folate and Vitamin B12 and the Potential Impact on Fetal Growth and Long-Term Metabolic Health in Diabetic Pregnancies. International Journal of Molecular Sciences 22:11, pages 5759.
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Amany Tawfik, Riyaz Mohamed, Dina Kira, Suhib Alhusban & Mohamed Al-Shabrawey. (2020) N-Methyl-D-aspartate receptor activation, novel mechanism of homocysteine-induced blood–retinal barrier dysfunction. Journal of Molecular Medicine 99:1, pages 119-130.
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Giulia Malaguarnera, Vito Emanuele Catania, Saverio Latteri, Antonio Maria Borzì, Gaetano Bertino, Roberto Madeddu, Filippo Drago & Michele Malaguarnera. (2020) Folate levels in hepatocellular carcinoma patients with portal vein thrombosis. BMC Gastroenterology 20:1.
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Christopher Gerner, Vincenzo Costigliola & Olga Golubnitschaja. (2019) MULTIOMIC PATTERNS IN BODY FLUIDS: TECHNOLOGICAL CHALLENGE WITH A GREAT POTENTIAL TO IMPLEMENT THE ADVANCED PARADIGM OF 3P MEDICINE. Mass Spectrometry Reviews 39:5-6, pages 442-451.
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Jianhua Wang, Craig Brown, Ce Shi, Justin Townsend, Giovana Rosa Gameiro, Peng Wang & Hong Jiang. (2019) Improving diabetic and hypertensive retinopathy with a medical food containing L-methylfolate: a preliminary report. Eye and Vision 6:1.
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Beatriz López‐Escobar, Bogdan J. Wlodarczyk, Jose Caro‐Vega, Ying Lin, Richard H. Finnell & Patricia Ybot‐González. (2019) The interaction of maternal diabetes with mutations that affect folate metabolism and how they affect the development of neural tube defects in mice. Developmental Dynamics 248:10, pages 900-917.
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Xunwen Lei, Guifeng Zeng, Yuemei Zhang, Qiang Li, Jinzhi Zhang, Zhenggang Bai & Kehu Yang. (2018) Association between homocysteine level and the risk of diabetic retinopathy: a systematic review and meta-analysis. Diabetology & Metabolic Syndrome 10:1.
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Zhenglin Wang, Wei Xing, Yongli Song, Hongli Li, Yonggang Liu, Yong Wang, Chun Li, Yun Wang, Yan Wu & Jing Han. (2018) Folic Acid Has a Protective Effect on Retinal Vascular Endothelial Cells against High Glucose. Molecules 23:9, pages 2326.
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Khaled Elmasry, Riyaz Mohamed, Isha Sharma, Nehal M. Elsherbiny, Yutao Liu, Mohamed Al-Shabrawey & Amany Tawfik. (2018) Epigenetic modifications in hyperhomocysteinemia: potential role in diabetic retinopathy and age-related macular degeneration. Oncotarget 9:16, pages 12562-12590.
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Prabha Gupta, Deepa John, Grace Rebekah & SheejaS John. (2018) Role of hyperhomocysteinemia in proliferative diabetic retinopathy: A case–control study. Indian Journal of Ophthalmology 66:10, pages 1435.
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Mariangela Malaguarnera, Vito Emanuele Catania, Antonio Maria Borzì, Stefano Malaguarnera, Roberto Madeddu, Gaetano Bertino & Saverio Latteri. (2018) Blood homocysteine levels are increased in hepatocellular carcinoma patients with portal vein thrombosis. A single centre retrospective cohort study. International Journal of Surgery Open 15, pages 60-65.
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Elizabeth Mazzio & Karam F. A. Soliman. 2018. Genomics-Driven Healthcare. Genomics-Driven Healthcare 263 279 .
Fedra Luciano-Mateo, Anna Hernández-Aguilera, Noemi Cabre, Jordi Camps, Salvador Fernández-Arroyo, Jose Lopez-Miranda, Javier Menendez & Jorge Joven. (2017) Nutrients in Energy and One-Carbon Metabolism: Learning from Metformin Users. Nutrients 9:2, pages 121.
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Giulia Malaguarnera, Vito Emanuele Catania, Antonio Francaviglia, Michele Malaguarnera, Filippo Drago, Massimo Motta & Saverio Latteri. (2016) Lipoprotein(a) in patients with hepatocellular carcinoma and portal vein thrombosis. Aging Clinical and Experimental Research 29:S1, pages 185-190.
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Priyia Pusparajah, Learn-Han Lee & Khalid Abdul Kadir. (2016) Molecular Markers of Diabetic Retinopathy: Potential Screening Tool of the Future?. Frontiers in Physiology 7.
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Olga Simó-Servat, Rafael Simó & Cristina Hernández. (2016) Circulating Biomarkers of Diabetic Retinopathy: An Overview Based on Physiopathology. Journal of Diabetes Research 2016, pages 1-13.
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Katie L. PenningtonMargaret M. Deangelis. (2016) Epigenetic Mechanisms of the Aging Human Retina. Journal of Experimental Neuroscience 9s2, pages JEN.S25513.
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