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OncoTargets and Therapy Volume 10, 2017 - Issue
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Original Research

Silencing of Foxp3 enhances the antitumor efficacy of GM-CSF genetically modified tumor cell vaccine against B16 melanoma

Antonio Miguel1 Department of Pharmacology, Faculty of Medicine, University of Valencia
,
Luis Sendra1 Department of Pharmacology, Faculty of Medicine, University of Valencia
,
Verónica Noé2 Department of Biochemistry and Molecular Biology, Faculty of Pharmacy, University of Barcelona
,
Carles J Ciudad2 Department of Biochemistry and Molecular Biology, Faculty of Pharmacy, University of Barcelona
,
Francisco Dasí3 Research University Hospital of Valencia, INCLIVA Health Research Institute;4 Department of Physiology, Faculty of Medicine, University of Valencia Foundation
,
David Hervas5 Biostatistics Unit
,
María José Herrero1 Department of Pharmacology, Faculty of Medicine, University of Valencia;6 Pharmacogenetics Unit, Instituto de Investigación Sanitaria La Fe (IIS La Fe)Correspondence[email protected]
&
Salvador F Aliño1 Department of Pharmacology, Faculty of Medicine, University of Valencia;7 Clinical Pharmacology Unit, ACM Hospital Universitario y Politécnico La Fe, Valencia, Spain
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Pages 503-514 | Published online: 23 Jan 2017

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Neda Mousavi-Niri, Maryam Naseroleslami & Jamshid Hadjati. (2019) Anti-regulatory T cell vaccines in immunotherapy: focusing on FoxP3 as target. Human Vaccines & Immunotherapeutics 15:3, pages 620-624.
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Xiaoyi Hu, Weilin Zhou, Ruyu Pi, Xia Zhao & Wei Wang. (2022) Genetically modified cancer vaccines: Current status and future prospects. Medicinal Research Reviews 42:4, pages 1492-1517.
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Lili Huang, Yeye Guo, Shujing Liu, Huaishan Wang, Jinjin Zhu, Lingling Ou & Xiaowei Xu. (2021) Targeting regulatory T cells for immunotherapy in melanoma. Molecular Biomedicine 2:1.
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Yan Xiong, Liqing Wang, Eros Di Giorgio, Tatiana Akimova, Ulf H. Beier, Rongxiang Han, Matteo Trevisanut, Jay H. Kalin, Philip A. Cole & Wayne W. Hancock. (2020) Inhibiting the coregulator CoREST impairs Foxp3+ Treg function and promotes antitumor immunity. Journal of Clinical Investigation 130:4, pages 1830-1842.
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Alexander Batista-Duharte, Luis Sendra, Maria Herrero, Damiana Téllez-Martínez, Iracilda Carlos & Salvador Aliño. (2020) Progress in the Use of Antisense Oligonucleotides for Vaccine Improvement. Biomolecules 10:2, pages 316.
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Jiantai Qiu, Donia Alson, Ta-Hsien Lee, Ching-Chou Tsai, Ting-Wei Yu, Yu-Sing Chen, Ya-Fang Cheng, Chu-Chi Lin & Scott Schuyler. (2019) Effect of Multiple Vaccinations with Tumor Cell-Based Vaccine with Codon-Modified GM-CSF on Tumor Growth in a Mouse Model. Cancers 11:3, pages 368.
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Alexander Batista-Duharte, Damiana Téllez-Martínez, Deivys Leandro Portuondo Fuentes & Iracilda Zeppone Carlos. (2018) Molecular adjuvants that modulate regulatory T cell function in vaccination: A critical appraisal. Pharmacological Research 129, pages 237-250.
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Afshin Namdar, Reza Mirzaei, Arash Memarnejadian, Roobina Boghosian, Morteza Samadi, Hamid Reza Mirzaei, Hamid Farajifard, Mehdi Zavar, Kayhan Azadmanesh, Shokrollah Elahi, Farshid Noorbakhsh, Abbas Rezaei & Jamshid Hadjati. (2017) Prophylactic DNA vaccine targeting Foxp3+ regulatory T cells depletes myeloid-derived suppressor cells and improves anti-melanoma immune responses in a murine model. Cancer Immunology, Immunotherapy 67:3, pages 367-379.
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Jinhua Wang, Wan Li, Ying Zhao, De Kang, Weiqi Fu, Xiangjin Zheng, Xiaocong Pang & Guanhua Du. (2018) Members of FOX family could be drug targets of cancers. Pharmacology & Therapeutics 181, pages 183-196.
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