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OncoTargets and Therapy Volume 9, 2016 - Issue

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Original Research

High-dose irradiation in combination with toll-like receptor 9 agonist CpG oligodeoxynucleotide 7909 downregulates PD-L1 expression via the NF-κB signaling pathway in non-small cell lung cancer cells

Xue Chen1 Department of Oncology, Jinshan Hospital, Medical Center of Fudan University

Qi Zhang1 Department of Oncology, Jinshan Hospital, Medical Center of Fudan University

Youjun Luo1 Department of Oncology, Jinshan Hospital, Medical Center of Fudan University

Caixia Gao1 Department of Oncology, Jinshan Hospital, Medical Center of Fudan University

Xibing Zhuang1 Department of Oncology, Jinshan Hospital, Medical Center of Fudan University

Guoxiong Xu2 Department of Center laboratory, Jinshan Hospital, Fudan University, Shanghai, People’s Republic of China

Tiankui Qiao1 Department of Oncology, Jinshan Hospital, Medical Center of Fudan UniversityCorrespondence[email protected]

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Pages 6511-6518 | Published online: 21 Oct 2016

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Zhu Lingling, Liu Jiewei, Wang Li, Yan Danli, Zhou Jie, Li Wen, Pu Dan, Peng Lei & Zhou Qinghua. (2020) Molecular regulatory network of PD-1/PD-L1 in non-small cell lung cancer. Pathology - Research and Practice 216:4, pages 152852.
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Zhansheng Jiang, Yanfang Yang, Yinli Yang, Yu Zhang, Zhensong Yue, Zhanyu Pan & Xiubao Ren. (2017) Ginsenoside Rg3 attenuates cisplatin resistance in lung cancer by downregulating PD-L1 and resuming immune. Biomedicine & Pharmacotherapy 96, pages 378-383.
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Hong Sun, Xiaoguang Han, Xiuhui Yan, Jingli Xu, Qiujing Huang, Fanqing Meng, Hongjin Zhang & Shufa Li. (2017) A novel mimovirus encoding ChgA 10–19 peptide with PD-L1 induces T cell tolerance and ameliorates the severity of diabetes. Cellular Immunology 320, pages 56-61.
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W Li, J Tu, X Liu & W Yang. (2017) Farnesyltransferase inhibitor FTI-277 inhibits PD-L1 expression on septic spleen lymphocytes and promotes spleen lymphocyte activation. Clinical and Experimental Immunology 190:1, pages 8-18.
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High-dose irradiation in combination with toll-like receptor 9 agonist CpG oligodeoxynucleotide 7909 downregulates PD-L1 expression via the NF-κB signaling pathway in non-small cell lung cancer cells

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High-dose irradiation in combination with toll-like receptor 9 agonist CpG oligodeoxynucleotide 7909 downregulates PD-L1 expression via the NF-κB signaling pathway in non-small cell lung cancer cells

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