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Case Series

Successful treatment with apatinib for refractory recurrent malignant gliomas: a case series

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Pages 837-845 | Published online: 14 Feb 2017

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Yong Wang, Xiangji Meng, Shizhen Zhou, Yufang Zhu, Jun Xu & Rongjie Tao. (2019) Apatinib Plus Temozolomide for Recurrent Glioblastoma: An Uncontrolled, Open-Label Study. OncoTargets and Therapy 12, pages 10579-10585.
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Dongdong Yu, Guang Han, Huali Liu, Likun Gao & Vivek Verma. (2019) Treatment of adult brainstem glioma with combined antiangiogenic therapy: a case report and literature review. OncoTargets and Therapy 12, pages 1333-1339.
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Articles from other publishers (21)

Jiayi Huang, Xiao Chen, Jinfeng Guo, Lin Song, Yanxi Mu, Han Zhao & Caiwen Du. (2022) Apatinib combined with trastuzumab and albumin‑bound paclitaxel for treatment of HER2+ breast cancer with brain metastases resistant to anti‑HER2 TKIs: A case report. Oncology Letters 25:2.
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Ming Zhang, Liying Gao, Xiaofeng Liu, Fang Dong, Qun Su, Yanping Zhang, Fengju Li, Hulan Wang & Pengbing Han. (2022) Low-Dose Apatinib Improves the Prognosis of Patients with Recurrent High-Grade Gliomas. Evidence-Based Complementary and Alternative Medicine 2022, pages 1-6.
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Hong-Hong Zhang, Xiao-Jing Du, Mei-Ling Deng, Lie Zheng, Dun-Chen Yao, Zhi-Qiang Wang, Qun-Ying Yang & Shao-Xiong Wu. (2022) Apatinib for recurrent/progressive glioblastoma multiforme: A salvage option. Frontiers in Pharmacology 13.
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Liang Xia, Mingjie Gong, Yangfan Zou, Zeng Wang, Bin Wu, Shuyuan Zhang, Liwen Li, Kai Jin & Caixing Sun. (2022) Apatinib Induces Ferroptosis of Glioma Cells through Modulation of the VEGFR2/Nrf2 Pathway. Oxidative Medicine and Cellular Longevity 2022, pages 1-15.
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Hang-Ping Wei, Jie Mao & Zu-Liang Hu. (2022) Successful apatinib treatment for advanced clear cell renal carcinoma as a first-line palliative treatment: A case report. World Journal of Clinical Cases 10:11, pages 3593-3600.
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Fuhua Lin, Chengcheng Guo, Qunying Yang, Yinsheng Chen, Chao Ke, Ke Sai, Ji Zhang, Xiaobing Jiang, Wanming Hu, Shaoyan Xi, Jian Zhou, Depei Li, Zhihuan Zhou, Qinqin Zhao, Xi Cao & Zhong-ping Chen. (2022) Initial report of a clinical trial evaluating the safety and efficiency of neoadjuvant camrelizumab and apatinib in patients with recurrent high-grade gliomas: A prospective, phase II, single-arm study. Glioma 5:1, pages 29.
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Hui Yao, Jiangang Liu, Chi Zhang, Yunxiang Shao, Xuetao Li, Zhengquan Yu & Yulun Huang. (2021) Apatinib inhibits glioma cell malignancy in patient-derived orthotopic xenograft mouse model by targeting thrombospondin 1/myosin heavy chain 9 axis. Cell Death & Disease 12:10.
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Gabriel Emilio Herrera-Oropeza, Carla Angulo-Rojo, Santos Alberto Gástelum-López, Alfredo Varela-Echavarría, Maribel Hernández-Rosales & Katia Aviña-Padilla. (2021) Glioblastoma multiforme: a multi-omics analysis of driver genes and tumour heterogeneity. Interface Focus 11:4.
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Hui Yao, Jiangang Liu, Chi Zhang, Yunxiang Shao, Xuetao Li, Ming Feng, Ximing Wang, Wenjuan Gan, Youxin Zhou & Yulun Huang. (2021) Clinical study of apatinib plus temozolomide for the treatment of recurrent high-grade gliomas. Journal of Clinical Neuroscience 90, pages 82-88.
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Zheng Chen, Xiangyu Wei, Xueyi Wang, Xuan Zheng, Bowen Chang, Lin Shen, Hanshuo Zhu, Min Yang, Shiting Li & Xuesheng Zheng. (2021) NDUFA4L2 promotes glioblastoma progression, is associated with poor survival, and can be effectively targeted by apatinib. Cell Death & Disease 12:4.
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Jun-Hui Guo, Yuan-Yuan Wang, Jiang-Wei Zhang, Pei-Min Liu, Yan-Jun Hao & Hai-Rui Duan. (2020) Clinical effects of apatinib mesylate for treatment of multiple brain micrometastases: Two case reports. World Journal of Clinical Cases 8:7, pages 1326-1336.
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Na Wang, Shubo Chen, Dengxiang Liu, Jun Guo, Yawei Sun, Juping Zhang, Qian Kong & Lili He. (2020) Therapeutic effect of small molecule targeting drug apatinib on gastric cancer and its role in prognosis and anti-infection mechanism. Saudi Journal of Biological Sciences 27:2, pages 606-610.
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Haozhe Piao, Ye Zhang, Chengcheng Guo, Li Zhu, Linan Liu, Ulrich Herrlinger, Felix Sahm & Zhong-ping Chen. (2020) East meets West for the treatment of glioma: A discussion of real-world cases. Glioma 3:1, pages 24.
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Zhong-ping Chen. (2019) Anti-angiogenic therapy for glioma: Puzzle and hope. Glioma 2:4, pages 182.
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Zedong Du, Yanxin Yu, Dajun Wu, Guangyu Zhang, Yang Wang, Liang He & RongQin Meng. (2018) Apatinib for salvage treatment of advanced malignant pleural mesothelioma. Medicine 97:45, pages e13105.
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Xiaofeng Li, Yueming He, Jinfeng Zhu, Hongxia Pang, Yongwei Lin & Jinyang Zheng. (2018) Apatinib-based targeted therapy against pulmonary sarcomatoid carcinoma: a case report and literature review. Oncotarget 9:72, pages 33734-33738.
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Ting Hu, Cuiwei Liu, Qiuhui Li, Jie Xiong, Yuxi Ma, Gang Wu & Yanxia Zhao. (2018) Apatinib + CPT-11 + S-1 for treatment of refractory brain metastases in patient with triple-negative breast cancer. Medicine 97:15, pages e0349.
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Miaomiao Gou, Haiyan Si, Yong Zhang, Niansong Qian, Zhikuan Wang, Weiwei Shi & Guanghai Dai. (2018) Efficacy and safety of apatinib in patients with previously treated metastatic colorectal cancer: a real-world retrospective study. Scientific Reports 8:1.
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Xiaoyun Liu, Yifan Zhang, Qian Chen, Yan Zhan, Quanren Wang, Chaoying Hu, Chen Yu, Zitao Guo, Xiaoyan Chen & Dafang Zhong. (2017) Pharmacokinetic Drug Interactions of Apatinib With Rifampin and Itraconazole. The Journal of Clinical Pharmacology 58:3, pages 347-356.
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Yong Zhou, Fan Tang, Yiying Wang, Li Min, Yi Luo, Wenli Zhang, Rui Shi, Hong Duan & Chongqi Tu. (2017) Advanced alveolar soft part sarcoma responds to apatinib. Oncotarget 8:30, pages 50314-50322.
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. (2017) Apatinib. Reactions Weekly 1650:1, pages 47-47.
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