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Review

Targeting the PD-1 pathway in pediatric solid tumors and brain tumors

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Pages 2097-2106 | Published online: 12 Apr 2017

Keep up to date with the latest research on this topic with citation updates for this article.

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Nikolai Siebert, Maxi Zumpe, Madlen Jüttner, Sascha Troschke-Meurer & Holger N. Lode. (2017) PD-1 blockade augments anti-neuroblastoma immune response induced by anti-GD2 antibody ch14.18/CHO. OncoImmunology 6:10.
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Articles from other publishers (36)

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Mieun Lee-Theilen, Delaine D. Fadini, Julia R. Hadhoud, Fleur van Dongen, Gabriela Kroll, Udo Rolle & Henning C. Fiegel. (2022) Hepatoblastoma Cancer Stem Cells Express PD-L1, Reveal Plasticity and Can Emerge upon Chemotherapy. Cancers 14:23, pages 5825.
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Aimée du Chatinier, Michaël H Meel, Arvid I Das, Dennis S Metselaar, Piotr Waranecki, Marianna Bugiani, Marjolein Breur, Erin F Simonds, Edbert D Lu, William A Weiss, Juan J Garcia Vallejo, Eelco W Hoving, Timothy N Phoenix & Esther Hulleman. (2022) Generation of immunocompetent syngeneic allograft mouse models for pediatric diffuse midline glioma. Neuro-Oncology Advances 4:1.
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Zahra Alipour, Kris Ann P Schultz, Ling Chen, Anne K Harris, Ivan A Gonzalez, John Pfeifer, D Ashley Hill, Mai He & Louis P Dehner. (2021) Programmed Death Ligand 1 Expression and Related Markers in Pleuropulmonary Blastoma. Pediatric and Developmental Pathology 24:6, pages 523-530.
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Enrico Munari, Francesca R. Mariotti, Linda Quatrini, Pietro Bertoglio, Nicola Tumino, Paola Vacca, Albino Eccher, Francesco Ciompi, Matteo Brunelli, Guido Martignoni, Giuseppe Bogina & Lorenzo Moretta. (2021) PD-1/PD-L1 in Cancer: Pathophysiological, Diagnostic and Therapeutic Aspects. International Journal of Molecular Sciences 22:10, pages 5123.
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Katia Perruccio, Angela Mastronuzzi, Marco Lupattelli, Francesco Arcioni, Ilaria Capolsini, Carla Cerri, Grazia M. I. Gurdo, Maria Speranza Massei, Elena Mastrodicasa & Maurizio Caniglia. (2021) Targeted Therapy with Sirolimus and Nivolumab in a Child with Refractory Multifocal Anaplastic Ependymoma. Reports 4:2, pages 12.
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Chenglong Chen, Lu Xie, Tingting Ren, Yi Huang, Jie Xu & Wei Guo. (2021) Immunotherapy for osteosarcoma: Fundamental mechanism, rationale, and recent breakthroughs. Cancer Letters 500, pages 1-10.
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Taranom Mobasheri, Elham Rayzan, Mahsima Shabani, Mina Hosseini, Ghanbar Mahmoodi Chalbatani & Nima Rezaei. (2020) Neuroblastoma‐targeted nanoparticles and novel nanotechnology‐based treatment methods. Journal of Cellular Physiology 236:3, pages 1751-1775.
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Neil Patel & Abby Green. 2021. Pediatric Transplant and Oncology Infectious Diseases. Pediatric Transplant and Oncology Infectious Diseases 22 33.e3 .
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Manuel A Silva, Nicolas Triltsch, Simon Leis, Ivan Kanchev, Tze Heng Tan, Benjamine Van Peel, Marian Van Kerckhoven, Vanessa Deschoolmeester & Johannes Zimmermann. (2020) Biomarker recommendation for PD‐1/PD‐L1 immunotherapy development in pediatric cancer based on digital image analysis of PD‐L1 and immune cells. The Journal of Pathology: Clinical Research 6:2, pages 124-137.
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Lihong Wang-Bishop, Mohamed Wehbe, Daniel Shae, Jamaal James, Benjamin C. Hacker, Kyle Garland, Plamen P. Chistov, Marjan Rafat, Justin M. Balko & John T. Wilson. (2020) Potent STING activation stimulates immunogenic cell death to enhance antitumor immunity in neuroblastoma. Journal for ImmunoTherapy of Cancer 8:1, pages e000282.
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I. V. Proleskovskaya, N. E. Konoplya & O. I. Bydanov. (2020) Treatment of relapse/progression of the disease in patients with neuroblastoma in the Republic of Belarus over a 20-year period: a cohort study. Russian Journal of Pediatric Hematology and Oncology 6:4, pages 40-47.
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Anna Gabrych, Rafał Pęksa, Michał Kunc, Małgorzata Krawczyk, Ewa Izycka-Swieszewska, Wojciech Biernat & Ewa Bień. (2019) The PD-L1/PD-1 axis expression on tumor-infiltrating immune cells and tumor cells in pediatric rhabdomyosarcoma. Pathology - Research and Practice 215:12, pages 152700.
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Brian Hutzen, Siddhi Nath Paudel, Meisam Naeimi Kararoudi, Kevin A. Cassady, Dean A. Lee & Timothy P. Cripe. (2019) Immunotherapies for pediatric cancer: current landscape and future perspectives. Cancer and Metastasis Reviews 38:4, pages 573-594.
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Klaus Rose & Philip D. Walson. (2019) Are Regulatory Age Limits in Pediatric Melanoma Justified?. Current Therapeutic Research 90, pages 113-118.
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Daniel A. Morgenstern & Meredith S. Irwin. 2019. Neuroblastoma. Neuroblastoma 263 281 .
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Takahiro Shimizu, Yasushi Fuchimoto, Hajime Okita, Kazumasa Fukuda, Yuko Kitagawa, Shigeru Ueno & Tatsuo Kuroda. (2018) A curative treatment strategy using tumor debulking surgery combined with immune checkpoint inhibitors for advanced pediatric solid tumors: An in vivo study using a murine model of osteosarcoma. Journal of Pediatric Surgery 53:12, pages 2460-2464.
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Mary Frances Wedekind, Nicholas L. Denton, Chun-Yu Chen & Timothy P. Cripe. (2018) Pediatric Cancer Immunotherapy: Opportunities and Challenges. Pediatric Drugs 20:5, pages 395-408.
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Mary F. Wedekind, Lars M. Wagner & Timothy P. Cripe. (2018) Immunotherapy for osteosarcoma: Where do we go from here?. Pediatric Blood & Cancer 65:9, pages e27227.
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Ricardo L. Pereira, Isis C. Nascimento, Ana P. Santos, Isabella E.Y. Ogusuku, Claudiana Lameu, Günter Mayer & Henning Ulrich. (2018) Aptamers: novelty tools for cancer biology. Oncotarget 9:42, pages 26934-26953.
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Vanessa P. Tolbert & Katherine K. Matthay. (2018) Neuroblastoma: clinical and biological approach to risk stratification and treatment. Cell and Tissue Research 372:2, pages 195-209.
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Akira Nakagawara, Yuanyuan Li, Hideki Izumi, Katsumi Muramori, Hiroko Inada & Masanori Nishi. (2018) Neuroblastoma. Japanese Journal of Clinical Oncology 48:3, pages 214-241.
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Nai-Kong V. Cheung & Estibaliz Lopez-Rodrigo. 2018. Reference Module in Biomedical Sciences. Reference Module in Biomedical Sciences.
Clare F. Malone & Kimberly Stegmaier. (2017) Scratching the Surface of Immunotherapeutic Targets in Neuroblastoma. Cancer Cell 32:3, pages 271-273.
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