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OncoTargets and Therapy Volume 10, 2017 - Issue

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Original Research

Asparaginyl endopeptidase improves the resistance of microtubule-targeting drugs in gastric cancer through IQGAP1 modulating the EGFR/JNK/ERK signaling pathway

Yuehong Cui1 Medical Oncology Department

Qian Li1 Medical Oncology Department

Hong Li1 Medical Oncology Department

Yan Wang1 Medical Oncology Department

Hongshan Wang2 General Surgery Department, Zhongshan Hospital, Fudan University, Shanghai, People’s Republic of China

Weidong Chen2 General Surgery Department, Zhongshan Hospital, Fudan University, Shanghai, People’s Republic of China

Shangmin Zhang3 Pathology Department, Yale School of Medicine, New Haven, CT, USA

Jian Cao3 Pathology Department, Yale School of Medicine, New Haven, CT, USA

Tianshu Liu1 Medical Oncology DepartmentCorrespondence[email protected]

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Pages 627-643 | Published online: 03 Feb 2017

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Xiaojing Xu, Mengling Liu, Ke Peng, Yiyi Yu & Tianshu Liu. (2023) Asparaginyl endopeptidase contributes to cetuximab resistance via MEK/ERK signaling in RAS wide-type metastatic colorectal cancer. Clinical and Translational Oncology 25:3, pages 776-785.
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Sayedeh Azimeh Hosseini, Alizamen Salehifard Jouneghani, Mahdi Ghatrehsamani, Hajar Yaghoobi, Fatemeh Elahian & Seyed Abbas Mirzaei. (2022) CRISPR/Cas9 as precision and high-throughput genetic engineering tools in gastrointestinal cancer research and therapy. International Journal of Biological Macromolecules 223, pages 732-754.
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Renata Sanches Almeida, Fernanda Wisnieski, Bruno Takao Real Karia & Marilia Arruda Cardoso Smith. (2022) CRISPR/Cas9 Genome-Editing Technology and Potential Clinical Application in Gastric Cancer. Genes 13:11, pages 2029.
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Binghong Chen, Mengying Wang, Junjun Qiu, Keman Liao, Wenrui Zhang, Qi Lv, Chunhui Ma, Zhongrun Qian, Zhonggang Shi, Rong Liang, Yan Lin, Jiazhou Ye, Yongming Qiu & Yingying Lin. (2022) Cleavage of tropomodulin-3 by asparagine endopeptidase promotes cancer malignancy by actin remodeling and SND1/RhoA signaling. Journal of Experimental & Clinical Cancer Research 41:1.
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Tao Wei & Paul F. Lambert. (2021) Role of IQGAP1 in Carcinogenesis. Cancers 13:16, pages 3940.
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Soudeh Ghafouri-Fard, Hamed Shoorei, Atefe Abak, Sayed Haidar Abbas Raza, Martin Pichler & Mohammad Taheri. (2021) Role of non-coding RNAs in modulating the response of cancer cells to paclitaxel treatment. Biomedicine & Pharmacotherapy 134, pages 111172.
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Yang Li, Jin-Shen Wang, Tao Zhang, Hong-Chang Wang & Le-Ping Li. (2020) Identification of New Therapeutic Targets for Gastric Cancer With Bioinformatics. Frontiers in Genetics 11.
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Maxim Sorokin, Elena Poddubskaya, Madina Baranova, Alex Glusker, Lali Kogoniya, Ekaterina Markarova, Daria Allina, Maria Suntsova, Victor Tkachev, Andrew Garazha, Marina Sekacheva & Anton Buzdin. (2020) RNA sequencing profiles and diagnostic signatures linked with response to ramucirumab in gastric cancer. Molecular Case Studies 6:2, pages a004945.
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Rui Cao, Wenping Song, Cheng Ye, Xiujun Liu, Liang Li, Yi Li, Hongjuan Yao, Xiaofei Zhou, Liang Li & Rongguang Shao. (2019) Internal enhancement of DNA damage by a novel bispecific antibody‐drug conjugate‐like therapeutics via blockage of mTOR and PD‐L1 signal pathways in pancreatic cancer. Cancer Medicine 8:2, pages 643-655.
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Asparaginyl endopeptidase improves the resistance of microtubule-targeting drugs in gastric cancer through IQGAP1 modulating the EGFR/JNK/ERK signaling pathway

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Asparaginyl endopeptidase improves the resistance of microtubule-targeting drugs in gastric cancer through IQGAP1 modulating the EGFR/JNK/ERK signaling pathway

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