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Original Research

Downregulation of DcR3 sensitizes hepatocellular carcinoma cells to TRAIL-induced apoptosis

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Pages 417-428 | Published online: 18 Jan 2017

Keep up to date with the latest research on this topic with citation updates for this article.

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Hua Ge, Chaojie Liang, Zhixia Li, Dali An, Shulin Ren, Chaosen Yue & Jixiang Wu. (2018) DcR3 induces proliferation, migration, invasion, and EMT in gastric cancer cells via the PI3K/AKT/GSK-3β/β-catenin signaling pathway. OncoTargets and Therapy 11, pages 4177-4187.
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Articles from other publishers (13)

Merve Kulbay, Adeline Paimboeuf, Derman Ozdemir & Jacques Bernier. (2021) Review of cancer cell resistance mechanisms to apoptosis and actual targeted therapies. Journal of Cellular Biochemistry 123:11, pages 1736-1761.
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Wei-Chin Chang, Yi-Chen Yeh, Hsiang-Ling Ho & Teh-Ying Chou. (2022) Deep exploration of immune function in EGFR wild-type and mutated lung adenocarcinomas by gene expression profiling: role of TRAIL-R2 (TNFRSF10B) in patient treatment and outcome. Human Pathology 126, pages 9-18.
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Farzaneh Karimi & Homa Mollaei. (2021) Potential of miRNAs in cervical cancer chemoresistance. Gene Reports 23, pages 101109.
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Mahmoud A. Younis, Ikramy A. Khalil & Hideyoshi Harashima. (2020) Gene Therapy for Hepatocellular Carcinoma: Highlighting the Journey from Theory to Clinical Applications. Advanced Therapeutics 3:11.
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Yahui Yang, Yifan Wang, Ligeng Xu & Tianfeng Chen. (2020) Dual-functional Se/Fe complex facilitates TRAIL treatment against resistant tumor cells via modulating cellular endoplasmic reticulum stress. Chinese Chemical Letters 31:7, pages 1801-1806.
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Cheng‐Yu Yang, Chih‐Kung Lin, Cheng‐Chih Hsieh, Chang‐Huei Tsao, Chun‐Shu Lin, Bo Peng, Yen‐Tzu Chen, Chun‐Chieh Ting, Wei‐Chin Chang, Gu‐Jiun Lin, Huey‐Kang Sytwu & Yuan‐Wu Chen. (2018) Anti‐oral cancer effects of triptolide by downregulation of DcR3 in vitro, in vivo, and in preclinical patient‐derived tumor xenograft model. Head & Neck 41:5, pages 1260-1269.
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Guang-Ming Li, Chao-Jie Liang, Dong-Xin Zhang, Li-Jun Zhang, Ji-Xiang Wu & Ying-Chen Xu. (2018) XB130 Knockdown Inhibits the Proliferation, Invasiveness, and Metastasis of Hepatocellular Carcinoma Cells and Sensitizes them to TRAIL-Induced Apoptosis. Chinese Medical Journal 131:19, pages 2320-2331.
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Hua Ge, Chaojie Liang, Shulin Ren, Chaosen Yue & Jixiang Wu. (2018) Prognostic value of DcR3 in solid tumors: A meta-analysis. Clinica Chimica Acta 481, pages 126-131.
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Lijuan Xie, Zhuo Chen, Hongyu Liu, Lianyue Guan, Zhanpeng Wang & Wei Li. (2018) Effects of miR-340 on hepatocellular carcinoma by targeting the DcR3 gene. Digestive and Liver Disease 50:3, pages 291-296.
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Dong-Yu Liang, Wei Huang, Qing Chang & Yan-Qiang Hou. (2018) ShDcR3 sensitizes TRAIL-resistant HCC cells by inducing caspase-dependent apoptosis while suppressing NF-κB dependent cFLIPL expression. PLOS ONE 13:2, pages e0191545.
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Junxin Li, Ni Xie, Jianhui Yuan, Lvyan Liu, Qiming Zhou, Xiaohu Ren, Qian Chen, Guizhong Zhang, Qingguo Ruan, Youhai H. Chen & Xiaochun Wan. (2017) DcR3 combined with hematological traits serves as a valuable biomarker for the diagnosis of cancer metastasis. Oncotarget 8:64, pages 107612-107620.
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Weijiang Zhang, Jianwei Zhou, Xiaoqing Zhu & Huadi Yuan. (2017) MiR-126 reverses drug resistance to TRAIL through inhibiting the expression of c-FLIP in cervical cancer. Gene 627, pages 420-427.
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Rui Zhang, Jian Xu, Jian Zhao & Jinghui Bai. (2017) Knockdown of miR-27a sensitizes colorectal cancer stem cells to TRAIL by promoting the formation of Apaf-1-caspase-9 complex. Oncotarget 8:28, pages 45213-45223.
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