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Original Research

Clarifying the molecular mechanism associated with carfilzomib resistance in human multiple myeloma using microarray gene expression profile and genetic interaction network

Zhihong ZhengDepartment of Hematology, Fujian Provincial Key Laboratory of Hematology, Fujian Medical University Union Hospital, Fuzhou, Fujian, People’s Republic of China

Tingbo LiuDepartment of Hematology, Fujian Provincial Key Laboratory of Hematology, Fujian Medical University Union Hospital, Fuzhou, Fujian, People’s Republic of China

Jing ZhengDepartment of Hematology, Fujian Provincial Key Laboratory of Hematology, Fujian Medical University Union Hospital, Fuzhou, Fujian, People’s Republic of China

Jianda HuDepartment of Hematology, Fujian Provincial Key Laboratory of Hematology, Fujian Medical University Union Hospital, Fuzhou, Fujian, People’s Republic of ChinaCorrespondence[email protected]

Pages 1327-1334 | Published online: 01 Mar 2017

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Assunta Melaccio, Antonia Reale, Ilaria Saltarella, Vanessa Desantis, Aurelia Lamanuzzi, Sebastiano Cicco, Maria Antonia Frassanito, Angelo Vacca & Roberto Ria. (2022) Pathways of Angiogenic and Inflammatory Cytokines in Multiple Myeloma: Role in Plasma Cell Clonal Expansion and Drug Resistance. Journal of Clinical Medicine 11:21, pages 6491.
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Ruqaia Abbas & Sarit Larisch. (2021) Killing by Degradation: Regulation of Apoptosis by the Ubiquitin-Proteasome-System. Cells 10:12, pages 3465.
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Ying Gao, Yudi Miao, Weihua Zhang, Xingli Ru & LiMin Hou. (2021) MicroRNA-365 induces apoptosis and inhibits invasion of human myeloma cells by targeting homeobox A9 (HOXA9). Environmental Toxicology and Pharmacology 85, pages 103627.
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Joske Ubels, Pieter Sonneveld, Martin H. van Vliet & Jeroen de Ridder. (2020) Gene Networks Constructed Through Simulated Treatment Learning can Predict Proteasome Inhibitor Benefit in Multiple Myeloma. Clinical Cancer Research 26:22, pages 5952-5961.
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G.R. Tundo, D. Sbardella, A.M. Santoro, A. Coletta, F. Oddone, G. Grasso, D. Milardi, P.M. Lacal, S. Marini, R. Purrello, G. Graziani & M. Coletta. (2020) The proteasome as a druggable target with multiple therapeutic potentialities: Cutting and non-cutting edges. Pharmacology & Therapeutics 213, pages 107579.
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Ting Liu, Jing Zhang, Kangdi Li, Lingnan Deng & Hongxiang Wang. (2020) Combination of an Autophagy Inducer and an Autophagy Inhibitor: A Smarter Strategy Emerging in Cancer Therapy. Frontiers in Pharmacology 11.
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Silpa Narayanan, Chao-Yun Cai, Yehuda G. Assaraf, Hui-Qin Guo, Qingbin Cui, Liuya Wei, Juan-Juan Huang, Charles R. AshbyJrJr & Zhe-Sheng Chen. (2020) Targeting the ubiquitin-proteasome pathway to overcome anti-cancer drug resistance. Drug Resistance Updates 48, pages 100663.
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Fang‑Xiao Zhu, Xiao‑Tao Wang, Hui‑Qiong Zeng, Zhi‑Hua Yin & Zhi‑Zhong Ye. (2019) A predicted risk score based on the expression of 16 autophagy‑related genes for multiple myeloma survival. Oncology Letters.
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Pawel Robak, Izabela Drozdz, Janusz Szemraj & Tadeusz Robak. (2018) Drug resistance in multiple myeloma. Cancer Treatment Reviews 70, pages 199-208.
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Xinhua Chen, Zhe Pei, Hao Peng & Zhihong Zheng. (2018) Exploring the molecular mechanism associated with breast cancer bone metastasis using bioinformatic analysis and microarray genetic interaction network. Medicine 97:37, pages e12032.
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Neale T. Hanke, Elliot Imler, Marilyn T. Marron, Bruce E. Seligmann, Linda L. Garland & Amanda F. Baker. (2018) Characterization of carfilzomib-resistant non-small cell lung cancer cell lines. Journal of Cancer Research and Clinical Oncology 144:7, pages 1317-1327.
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Roberta Ettari, Maria Zappalà, Silvana Grasso, Caterina Musolino, Vanessa Innao & Alessandro Allegra. (2018) Immunoproteasome-selective and non-selective inhibitors: A promising approach for the treatment of multiple myeloma. Pharmacology & Therapeutics 182, pages 176-192.
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Clarifying the molecular mechanism associated with carfilzomib resistance in human multiple myeloma using microarray gene expression profile and genetic interaction network

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Clarifying the molecular mechanism associated with carfilzomib resistance in human multiple myeloma using microarray gene expression profile and genetic interaction network

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