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OncoTargets and Therapy Volume 10, 2017 - Issue
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Original Research

Silencing of AQP3 induces apoptosis of gastric cancer cells via downregulation of glycerol intake and downstream inhibition of lipogenesis and autophagy

Liang ChenDepartment of General Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, People’s Republic of China
,
Zheng LiDepartment of General Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, People’s Republic of China
,
Qiang ZhangDepartment of General Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, People’s Republic of China
,
Song WeiDepartment of General Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, People’s Republic of China
,
Bowen LiDepartment of General Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, People’s Republic of China
,
Xuan ZhangDepartment of General Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, People’s Republic of China
,
Lei ZhangDepartment of General Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, People’s Republic of China
,
Qing LiDepartment of General Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, People’s Republic of China
,
Hao XuDepartment of General Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, People’s Republic of ChinaCorrespondence[email protected] [email protected]
&
Zekuan XuDepartment of General Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, People’s Republic of ChinaCorrespondence[email protected] [email protected]
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Pages 2791-2804 | Published online: 01 Jun 2017

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Kija Malale, Jili Fu, Liewang Qiu, Ke Zhan, Xiuni Gan & Zhechuan Mei. (2020) RETRACTED ARTICLE: Hypoxia-Induced Aquaporin-3 Changes Hepatocellular Carcinoma Cell Sensitivity to Sorafenib by Activating the PI3K/Akt Signaling Pathway. Cancer Management and Research 12, pages 4321-4333.
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Articles from other publishers (16)

Abudumijiti Abulizi, Awaguli Dawuti & Baoxue Yang. 2023. Aquaporins. Aquaporins 303 315 .
Rui Wang, Xuejian Wang, Jun Zhao, Jiacheng Jin, Weiwei Fan, Xinqing Zhu, Qiwei Chen, Baochang Zhang, Lan Lan, Kexin Qu, Liang Zhu & Jianbo Wang. (2022) Clinical value and molecular mechanism of AQGPs in different tumors. Medical Oncology 39:11.
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Dandan Liu, Duo Shi, Lin Xu, Lingling Sun, Shuzhen Liu & Bing Luo. (2022) LMP2A inhibits the expression of KLF5 through the mTORC1 pathway in EBV-associated gastric carcinoma. Virus Research 315, pages 198792.
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Andreia de Almeida, Dimitris Parthimos, Holly Dew, Oliver Smart, Marie Wiltshire & Rachel J. Errington. (2021) Aquaglyceroporin-3’s Expression and Cellular Localization Is Differentially Modulated by Hypoxia in Prostate Cancer Cell Lines. Cells 10:4, pages 838.
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M.S. Lekshmy, T.T. Sivakumar, Anna P. Joseph, B.R. Varun, Vinod Mony & A. Reshmi. (2021) Expression of transmembrane protein aquaporin-3 in oral epithelial dysplasia and oral squamous cell carcinoma. Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology 131:2, pages 202-208.
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Pak Hin Chow, Joanne Bowen & Andrea J Yool. (2020) Combined Systematic Review and Transcriptomic Analyses of Mammalian Aquaporin Classes 1 to 10 as Biomarkers and Prognostic Indicators in Diverse Cancers. Cancers 12:7, pages 1911.
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Shuhua Wang, Yuanyuan Wu, Shenghua Yang, Xunchao Liu, Yong Lu, Fengxia Liu, Guixia Li & Guirong Tian. (2020) miR ‐874 directly targets AQP3 to inhibit cell proliferation, mobility and EMT in non‐small cell lung cancer . Thoracic Cancer 11:6, pages 1550-1558.
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Yunmei Sun, Rui Cai, Yingqian Wang, Rui Zhao, Jin Qin & Weijun Pang. (2020) A Newly Identified LncRNA LncIMF4 Controls Adipogenesis of Porcine Intramuscular Preadipocyte through Attenuating Autophagy to Inhibit Lipolysis. Animals 10:6, pages 926.
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Mei Shang, Hengchang Sun, Yinjuan Wu, Yu Gong, Zeli Tang, Fangang Meng, Lei He, Xinbing Yu, Yan Huang & Xuerong Li. (2020) In vivo and in vitro studies using Clonorchis sinensis adult-derived total protein (CsTP) on cellular function and inflammatory effect in mouse and cell model. Parasitology Research 119:5, pages 1641-1652.
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Xiaoyu Wang, Jing Yang, Ying Yao, Xin’E Shi, Gongshe Yang & Xiao Li. (2020) AQP3 Facilitates Proliferation and Adipogenic Differentiation of Porcine Intramuscular Adipocytes. Genes 11:4, pages 453.
Crossref
Tomas Koltai, Stephan J. Reshkin & Salvador Harguindey. 2020. An Innovative Approach to Understanding and Treating Cancer: Targeting pH. An Innovative Approach to Understanding and Treating Cancer: Targeting pH 205 241 .
Giuseppe Calamita, Jason Perret & Christine Delporte. (2018) Aquaglyceroporins: Drug Targets for Metabolic Diseases?. Frontiers in Physiology 9.
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Mingjie Yang, Yingmei Zhang & Jun Ren. (2018) Autophagic Regulation of Lipid Homeostasis in Cardiometabolic Syndrome. Frontiers in Cardiovascular Medicine 5.
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Zhongyuan He, Zheng Li, Xuan Zhang, Kai Yin, Weizhi Wang, Zhipeng Xu, Bowen Li, Lei Zhang, Jianghao Xu, Guangli Sun, Lu Wang, Qing Li, Xiaoxu Huang, Lu Zhang, Diancai Zhang, Hao Xu & Zekuan Xu. (2018) MiR-422a regulates cellular metabolism and malignancy by targeting pyruvate dehydrogenase kinase 2 in gastric cancer. Cell Death & Disease 9:5.
Crossref
Brian A. Boone, Herbert J. ZehIIIIII & Nathan Bahary. (2018) Autophagy Inhibition in Pancreatic Adenocarcinoma. Clinical Colorectal Cancer 17:1, pages 25-31.
Crossref
Mingjie Yang, Yingmei Zhang & Jun Ren. 2018. Autophagy and Cardiometabolic Diseases. Autophagy and Cardiometabolic Diseases 127 135 .

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