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Original Research

RETRACTED ARTICLE: Emodin suppresses proliferation, migration and invasion in ovarian cancer cells by down regulating ILK in vitro and in vivo

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Pages 3579-3589 | Published online: 19 Jul 2017

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (4)

Weipeng Wei, Jianhua Tang, Hongfang Li, Yongsheng Huang, Chengchen Yin, Dan Li & Fushan Tang. (2021) Antitumor Effects of Self-Assembling Peptide-Emodin in situ Hydrogels in vitro and in vivo. International Journal of Nanomedicine 16, pages 47-60.
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Jia Gu, Sunil Rauniyar, Yan Wang, Wenjian Zhan, Chengkun Ye, Shaogan Ji & Guanzheng Liu. (2021) Chrysophanol Induced Glioma Cells Apoptosis via Activation of Mitochondrial Apoptosis Pathway. Bioengineered 12:1, pages 6855-6868.
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Qiaomei Zheng, Jinhua Wang, Wenwen Li, Xiaoyun Chen, Shaozhan Chen & Lihong Chen. (2020) Emodin Reverses the Epithelial–Mesenchymal Transition of Human Endometrial Stromal Cells by Inhibiting ILK/GSK-3β Pathway. Drug Design, Development and Therapy 14, pages 3663-3672.
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Weipeng Wei, Cui Meng, Yuhe Wang, Yongsheng Huang, Wenbin Du, Hongfang Li, Yanfei Liu, Hong Song & Fushan Tang. (2019) The interaction between self – assembling peptides and emodin and the controlled release of emodin from in-situ hydrogel. Artificial Cells, Nanomedicine, and Biotechnology 47:1, pages 3961-3975.
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Articles from other publishers (20)

Jeong-Yub Kim, Chan-Woong Jung, Won Seok Lee, Hyeon-Jeong Jeong, Myung-Jin Park, Won Il Jang & Eun Ho Kim. (2022) Emodin coupled with high LET neutron beam—a novel approach to treat on glioblastoma. Journal of Radiation Research 63:6, pages 817-827.
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Paul C. McDonald & Shoukat Dedhar. (2022) New Perspectives on the Role of Integrin-Linked Kinase (ILK) Signaling in Cancer Metastasis. Cancers 14:13, pages 3209.
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Li Xu, Yiyun Liu, Yangsheng Chen, Ruihong Zhu, Siqi Li, Songyan Zhang, Jian Zhang, Heidi Qunhui Xie & Bin Zhao. (2022) Emodin inhibits U87 glioblastoma cells migration by activating aryl hydrocarbon receptor (AhR) signaling pathway. Ecotoxicology and Environmental Safety 234, pages 113357.
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Fen‐Lan Wu, Pei‐Yi Chu, Guan‐Yu Chen, Ke Wang, Wei‐Yu Hsu, Azaj Ahmed, Wen‐Lung Ma, Wei‐Chung Cheng, Yang‐Chang Wu & Juan‐Cheng Yang. (2021) Natural anthraquinone compound emodin as a novel inhibitor of aurora A kinase: A pilot study. Chemical Biology & Drug Design 99:1, pages 126-135.
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Wayne Carver, Ethan Fix, Charity Fix, Daping Fan, Mrinmay Chakrabarti & Mohamad Azhar. (2021) Effects of emodin, a plant‐derived anthraquinone, on TGF‐β1‐induced cardiac fibroblast activation and function. Journal of Cellular Physiology 236:11, pages 7440-7449.
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Qi Zheng, Shuo Li, Xiaojiaoyang Li & Runping Liu. (2021) Advances in the study of emodin: an update on pharmacological properties and mechanistic basis. Chinese Medicine 16:1.
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Monika Stompor-Gorący. (2021) The Health Benefits of Emodin, a Natural Anthraquinone Derived from Rhubarb—A Summary Update. International Journal of Molecular Sciences 22:17, pages 9522.
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Saleh Almasabi, Afsar U. Ahmed, Richard Boyd & Bryan R. G. Williams. (2021) A Potential Role for Integrin-Linked Kinase in Colorectal Cancer Growth and Progression via Regulating Senescence and Immunity. Frontiers in Genetics 12.
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Hardeep Singh Tuli, Vaishali Aggarwal, Muobarak Tuorkey, Diwakar Aggarwal, Nidarshana Chaturvedi Parashar, Mehmet Varol, Raj Savla, Ginpreet Kaur, Sonam Mittal & Katrin Sak. (2021) Emodin: A metabolite that exhibits anti-neoplastic activities by modulating multiple oncogenic targets. Toxicology in Vitro 73, pages 105142.
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Esra Küpeli Akkol, Iffet Irem Tatlı, Gökçe Şeker Karatoprak, Osman Tuncay Ağar, Çiğdem Yücel, Eduardo Sobarzo-Sánchez & Raffaele Capasso. (2021) Is Emodin with Anticancer Effects Completely Innocent? Two Sides of the Coin. Cancers 13:11, pages 2733.
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Ning Zhang, Jiawen Wang, Aimin Sheng, Shuo Huang, Yanyan Tang, Shitang Ma & Ge Hong. (2021) Emodin Inhibits the Proliferation of MCF-7 Human Breast Cancer Cells Through Activation of Aryl Hydrocarbon Receptor (AhR). Frontiers in Pharmacology 11.
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Ya CUI, Liu-Jing CHEN, Tu HUANG, Jian-Qiong YING & Juan LI. (2020) The pharmacology, toxicology and therapeutic potential of anthraquinone derivative emodin. Chinese Journal of Natural Medicines 18:6, pages 425-435.
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Viana Castañeda-Loaiza, Chloé Placines, Maria João Rodrigues, Catarina Pereira, Gokhan Zengin, Ahmet Uysal, József Jeko, Zoltán Cziáky, Catarina Pinto Reis, Maria Manuela Gaspar & Luísa Custódio. (2020) If you cannot beat them, join them: Exploring the fruits of the invasive species Carpobrotus edulis (L.) N.E. Br as a source of bioactive products. Industrial Crops and Products 144, pages 112005.
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Hua Luo, Chi Teng Vong, Hanbin Chen, Yan Gao, Peng Lyu, Ling Qiu, Mingming Zhao, Qiao Liu, Zehua Cheng, Jian Zou, Peifen Yao, Caifang Gao, Jinchao Wei, Carolina Oi Lam Ung, Shengpeng Wang, Zhangfeng Zhong & Yitao Wang. (2019) Naturally occurring anti-cancer compounds: shining from Chinese herbal medicine. Chinese Medicine 14:1.
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Zibo Li, Yukun Lin, Shuhui Zhang, Lin Zhou, Guixi Yan, Yuehua Wang, Mengdi Zhang, Mengqi Wang, Haihong Lin, Qiaozhen Tong, Yongjian Duan & Gangjun Du. (2019) Emodin regulates neutrophil phenotypes to prevent hypercoagulation and lung carcinogenesis. Journal of Translational Medicine 17:1.
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Cherry Yin-Yi Chang, Pei-Yuu Yang, Fuu-Jen Tsai, Te-Mao Li, Jian-Shiun Chiou, Chao-Jung Chen, Ting-Hsu Lin, Chiu-Chu Liao, Shao-Mei Huang, Bo Ban, Wen-Miin Liang & Ying-Ju Lin. (2019) Integrated Chinese Herbal Medicine Therapy Improves the Survival of Patients With Ovarian Cancer. Integrative Cancer Therapies 18, pages 153473541988149.
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Whasun Lim, Yikyung An, Changwon Yang, Fuller W. Bazer & Gwonhwa Song. (2018) Chrysophanol induces cell death and inhibits invasiveness via mitochondrial calcium overload in ovarian cancer cells. Journal of Cellular Biochemistry 119:12, pages 10216-10227.
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Cong Zu, Guangyuan Qin, Chunshu Yang, Ning Liu, Anning He, Mingdi Zhang & Xinyu Zheng. (2018) Low dose Emodin induces tumor senescence for boosting breast cancer chemotherapy via silencing NRARP. Biochemical and Biophysical Research Communications 505:4, pages 973-978.
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Yun-duan Song, Xiao-zong Li, Ya-xian Wu, Yao Shen, Fang-fang Liu, Pei-pei Gao, Lei Sun & Feng Qian. (2018) Emodin alleviates alternatively activated macrophage and asthmatic airway inflammation in a murine asthma model. Acta Pharmacologica Sinica 39:8, pages 1317-1325.
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Zhiyuan Liang & Chunfeng Ren. (2018) RETRACTED: Emodin attenuates apoptosis and inflammation induced by LPS through up-regulating lncRNA TUG1 in murine chondrogenic ATDC5 cells. Biomedicine & Pharmacotherapy 103, pages 897-902.
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