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Original Research

PUMA mediates the anti-cancer effect of osimertinib in colon cancer cells

Lingchuan Guo1 Department of Pathology, Hospital of Suzhou University, Suzhou

Shan Huang1 Department of Pathology, Hospital of Suzhou University, Suzhou

Xinwei Wang2 Department of Oncology, Tumor Hospital of Jiangsu Province, Nanjing, Jiangsu, ChinaCorrespondence[email protected]

Pages 5281-5288 | Published online: 03 Nov 2017

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Febri Wulandari, Muthi' Ikawati, Edy Meiyanto, Mitsunori Kirihata & Adam Hermawan. (2020) Bioinformatic analysis of CCA-1.1, a novel curcumin analog, uncovers furthermost noticeable target genes in colon cancer. Gene Reports 21, pages 100917.
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Romane Florent, Louis-Bastien Weiswald, Bernard Lambert, Emilie Brotin, Edwige Abeilard, Marie-Hélène Louis, Guillaume Babin, Laurent Poulain & Monique N’Diaye. (2020) Bim, Puma and Noxa upregulation by Naftopidil sensitizes ovarian cancer to the BH3-mimetic ABT-737 and the MEK inhibitor Trametinib. Cell Death & Disease 11:5.
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Liangjun Li, Lin Lin, Ming Li & Weiling Li. (2019) Gilteritinib induces PUMA‐dependent apoptotic cell death via AKT/GSK‐3β/NF‐κB pathway in colorectal cancer cells. Journal of Cellular and Molecular Medicine 24:3, pages 2308-2318.
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Ping Jin, Jingwen Jiang, Na Xie, Li Zhou, Zhao Huang, Lu Zhang, Siyuan Qin, Shuyue Fu, Liyuan Peng, Wei Gao, Bowen Li, Yunlong Lei, Edouard C. Nice, Changlong Li, Jichun Shao & Ke Xie. (2019) MCT1 relieves osimertinib-induced CRC suppression by promoting autophagy through the LKB1/AMPK signaling. Cell Death & Disease 10:8.
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Takashi Higuchi, Hiromichi Oshiro, Zhiying Zhang, Kentaro Miyake, Norihiko Sugisawa, Yuki Katsuya, Norio Yamamoto, Katsuhiro Hayashi, Hiroaki Kimura, Shinji Miwa, Kentaro Igarashi, Ming Zhao, Michael Bouvet, Shree Ram Singh, Hiroyuki Tsuchiya & Robert M Hoffman. (2019) Osimertinib Regresses an EGFR-Mutant Cisplatinum- Resistant Lung Adenocarcinoma Growing in the Brain in Nude Mice. Translational Oncology 12:4, pages 640-645.
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Donatella Romaniello, Luigi Mazzeo, Maicol Mancini, Ilaria Marrocco, Ashish Noronha, Matthew Kreitman, Swati Srivastava, Soma Ghosh, Moshit Lindzen, Tomer Meir Salame, Amir Onn, Jair Bar & Yosef Yarden. (2018) A Combination of Approved Antibodies Overcomes Resistance of Lung Cancer to Osimertinib by Blocking Bypass Pathways. Clinical Cancer Research 24:22, pages 5610-5621.
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Bahriye Karakas, Yeliz Ozmay, Huveyda Basaga, Ozgur Gul & Ozgur Kutuk. (2018) Distinct apoptotic blocks mediate resistance to panHER inhibitors in HER2+ breast cancer cells. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1865:8, pages 1073-1087.
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Zheng-Hai Tang & Jin-Jian Lu. (2018) Osimertinib resistance in non-small cell lung cancer: Mechanisms and therapeutic strategies. Cancer Letters 420, pages 242-246.
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PUMA mediates the anti-cancer effect of osimertinib in colon cancer cells

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PUMA mediates the anti-cancer effect of osimertinib in colon cancer cells

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