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Original Research

Apatinib in the treatment of advanced lung adenocarcinoma with KRAS mutation

Da-xiong ZengDepartment of Respiratory and Critical Care, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, People’s Republic of China

Chang-guo WangDepartment of Respiratory and Critical Care, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, People’s Republic of China

Jian-an HuangDepartment of Respiratory and Critical Care, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, People’s Republic of China

Jun-hong JiangDepartment of Respiratory and Critical Care, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, People’s Republic of ChinaCorrespondence[email protected]

Pages 4269-4272 | Published online: 28 Aug 2017

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Shaila A. Shetu & Debasish Bandyopadhyay. (2022) Small-Molecule RAS Inhibitors as Anticancer Agents: Discovery, Development, and Mechanistic Studies. International Journal of Molecular Sciences 23:7, pages 3706.
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Ying-ying Liu, Tao Chen, Dan Shen, Wei-yun Zhang, Chang-guo Wang, Jun-hong Jiang & Da-xiong Zeng. (2019) Low-dose apatinib monotherapy in advanced chemotherapy-refractory small cell lung cancer: a case series and literature review. Journal of International Medical Research 48:3, pages 030006051988727.
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Jian Li, Xiwen Tong & Hongtao Li. (2020) Efficacy and safety of apatinib monotherapy in elderly patients with advanced metastatic non-small cell lung cancer. Indian Journal of Cancer 57:1, pages 13.
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Aiyi Li, Kong Wang, Aiguo Xu, Gang Wang, Yongchang Miao, Zhichao Sun & Jingyu Zhang. (2019) Apatinib as an optional treatment in metastatic colorectal cancer. Medicine 98:35, pages e16919.
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Da-xiong Zeng, Wei Lei, Chang-guo Wang, Jian-an Huang & Jun-hong Jiang. (2018) Low dosage of apatinib monotherapy as rescue treatment in advanced lung squamous cell carcinoma. Cancer Chemotherapy and Pharmacology 83:3, pages 439-442.
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Da-Xiong Zeng, Jian-An Huang & Jun-Hong Jiang. (2019) Apatinib as Salvage Treatment in BRCA2-Mutated Advanced Lung Adenocarcinoma. American Journal of Therapeutics 26:6, pages e747-e748.
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Jun Jin, Jiahao Du & Yanwei Wu. (2019) Apatinib monotherapy for advanced VEGFR-2-negative nasopharyngeal carcinoma. Medicine 98:1, pages e13491.
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Di Zhang, Chufeng Zhang, Jiaqi Huang, Yan Guan & Qisen Guo. (2018) Clinical investigation of the efficacy and toxicity of apatinib (YN968D1) in stage III/IV non-small cell lung cancer after second-line chemotherapy treatment: A retrospective study. Thoracic Cancer 9:12, pages 1754-1762.
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Zui Liu, Wei Ou, Ning Li & Si-Yu Wang. (2018) Apatinib monotherapy for advanced non-small cell lung cancer after the failure of chemotherapy or other targeted therapy. Thoracic Cancer 9:10, pages 1285-1290.
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Xiaofeng Li, Yueming He, Jinfeng Zhu, Hongxia Pang, Yongwei Lin & Jinyang Zheng. (2018) Apatinib-based targeted therapy against pulmonary sarcomatoid carcinoma: a case report and literature review. Oncotarget 9:72, pages 33734-33738.
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Apatinib in the treatment of advanced lung adenocarcinoma with KRAS mutation

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