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OncoTargets and Therapy Volume 10, 2017 - Issue
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Original Research

Apatinib plus icotinib in treating advanced non-small cell lung cancer after icotinib treatment failure: a retrospective study

Jianping XuDepartment of Medical Oncology, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing Key Laboratory of Clinical Study on Anticancer Molecular Targeted Drugs, Beijing, People’s Republic of China
,
Xiaoyan LiuDepartment of Medical Oncology, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing Key Laboratory of Clinical Study on Anticancer Molecular Targeted Drugs, Beijing, People’s Republic of China
,
Sheng YangDepartment of Medical Oncology, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing Key Laboratory of Clinical Study on Anticancer Molecular Targeted Drugs, Beijing, People’s Republic of China
,
Xiangru ZhangDepartment of Medical Oncology, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing Key Laboratory of Clinical Study on Anticancer Molecular Targeted Drugs, Beijing, People’s Republic of China
&
Yuankai ShiDepartment of Medical Oncology, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing Key Laboratory of Clinical Study on Anticancer Molecular Targeted Drugs, Beijing, People’s Republic of ChinaCorrespondence[email protected]
Pages 4989-4995 | Published online: 13 Oct 2017

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Yingjie Ma, Junxian Yu, Qin Li, Qiang Su & Bangwei Cao. (2020) Addition of docosahexaenoic acid synergistically enhances the efficacy of apatinib for triple-negative breast cancer therapy. Bioscience, Biotechnology, and Biochemistry 84:4, pages 743-756.
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Shen-Cun Fang, Wen Huang, Ying-Ming Zhang, Hai-Tao Zhang & Wei-Ping Xie. (2019) Hypertension as a predictive biomarker in patients with advanced non-small-cell lung cancer treated with apatinib. OncoTargets and Therapy 12, pages 985-992.
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Jiangtao Yu, Ziwen Xu, Anyang Li, Jindi Zhang, Yi Wang, Hongqin Zhao & Haiyan Zhu. (2019) The Efficacy And Safety Of Apatinib Treatment For Patients With Metastatic Or Recurrent Cervical Cancer: A Retrospective Study. Drug Design, Development and Therapy 13, pages 3419-3424.
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Jun Wu, Jing Wang, Qiang Su, Wei Ding, Teng Li, Junxian Yu & Bangwei Cao. (2018) Traditional Chinese medicine Astragalus polysaccharide enhanced antitumor effects of the angiogenesis inhibitor apatinib in pancreatic cancer cells on proliferation, invasiveness, and apoptosis. OncoTargets and Therapy 11, pages 2685-2698.
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Articles from other publishers (11)

Jijin Wang, Di Huang, Wenjing Yang, Qingxu Song, Yibin Jia, Pengxiang Chen & Yufeng Cheng. (2022) The efficacy and safety of Apatinib in the treatment of advanced non-small cell lung cancer: A retrospective trial. Frontiers in Oncology 12.
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Xiao Xiao Li. (2022) Low-Dosage Apatinib in Treating Advanced Pulmonary Adenocarcinoma With Kras Mutation After Osimertinib Resistance: A Case Report. American Journal of Therapeutics 29:2, pages e269-e271.
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Mingyue Zou, Zhenhua Zhao, Bingqian Zhang, Haijia Mao, Yanan Huang & Cheng Wang. (2021) Pulmonary lesions: correlative study of dynamic triple-phase enhanced CT perfusion imaging with tumor angiogenesis and vascular endothelial growth factor expression. BMC Medical Imaging 21:1.
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Xue Yang, Yang Xia, Liyan Xu, Li Liang, Minglei Zhuo, Meina Wu, Tongtong An, Ziping Wang, Yuyan Wang, Jianjie Li, Jia Zhong, Hanxiao Chen, Bo Jia, Jingjing Wang & Jun Zhao. (2021) Efficacy and Safety of Combination Treatment With Apatinib and Osimertinib After Osimertinib Resistance in Epidermal Growth Factor Receptor-Mutant Non-small Cell Lung Carcinoma—A Retrospective Analysis of a Multicenter Clinical Study. Frontiers in Molecular Biosciences 8.
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Fen Wang, Xia Yuan, Jun Jia, Xiaoxia Bi, Zeqiang Zhou, Qiming Zhou, Xia Li, Changguo Luo, Minghui Deng, Liangjie Yi, Yong Li, Jianxin Lu, Wenzhi Su, Hanbin Chen, Yu Zhu & Shubin Wang. (2020) Apatinib Monotherapy for Chemotherapy-Refractory Metastatic Colorectal Cancer: A Multi-centre, Single-Arm, Prospective Study. Scientific Reports 10:1.
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Jian-Chun Duan, Zhi-Jie Wang, Lin Lin, Jun-Ling Li, Yan Wang, Hua Bai, Xing-Sheng Hu, Yu-Tao Liu, Xue-Zhi Hao, Hong-Yu Wang, Rui Wan, Xin Wang & Jie Wang. (2019) Apatinib, a novel VEGFR inhibitor plus docetaxel in advanced lung adenocarcinoma patients with wild-type EGFR: a phase I trial. Investigational New Drugs 37:4, pages 731-737.
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Anjie Zhu, Peng Yuan, Jiayu Wang, Ying Fan, Yang Luo, Ruigang Cai, Pin Zhang, Qing Li, Fei Ma & Binghe Xu. (2019) Apatinib combined with chemotherapy in patients with previously treated advanced breast cancer: An observational study. Oncology Letters.
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Di Zhang, Chufeng Zhang, Jiaqi Huang, Yan Guan & Qisen Guo. (2018) Clinical investigation of the efficacy and toxicity of apatinib (YN968D1) in stage III/IV non-small cell lung cancer after second-line chemotherapy treatment: A retrospective study. Thoracic Cancer 9:12, pages 1754-1762.
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Jie-Tao Ma, Jing Sun, Li Sun, Shu-Ling Zhang, Le-Tian Huang & Cheng-Bo Han. (2018) Efficacy and safety of apatinib in patients with advanced nonsmall cell lung cancer that failed prior chemotherapy or EGFR-TKIs. Medicine 97:35, pages e12083.
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Lu Yang, Sheng Yang, Yutao Liu, Junling Li, Xingsheng Hu, Yalei Wang, Yan Zhang & Yan Wang. (2018) Combination TS‐1 plus EGFR‐tyrosine kinase inhibitors (TKIs) for the treatment of non‐small cell lung cancer after progression on first‐line or further EGFR‐TKIs: A phase II, single‐arm trial. Thoracic Cancer 9:6, pages 693-698.
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Siqi Feng, Jingwei Zhang, Ying Wang, Runbin Sun, Dong Feng, Ying Peng, Na Yang, Yue Zhang, Haoxue Gao, Huilin Gu, Guangji Wang, Jiye Aa & Fang Zhou. (2018) Application of liquid chromatography–tandem mass spectrometry to study the effect of docetaxel on pharmacokinetics and tissue distribution of apatinib in mice. Journal of Chromatography B 1083, pages 198-203.
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