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Original Research

DNA fragmentation factors 40 and 45 (DFF40/DFF45) and B-cell lymphoma 2 (Bcl-2) protein are underexpressed in uterine leiomyosarcomas and may predict survival

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Pages 4579-4589 | Published online: 14 Sep 2017

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Sabina Enlund, Indranil Sinha, Amanda Ramilo Amor, Shahrzad Shirazi Fard, Ekaterina Pokrovskaja Tamm, Qingfei Jiang, Vanessa Lundin, Anna Nilsson & Frida Holm. (2022) Malignant DFFB isoform switching promotes leukemia survival in relapse pediatric T‐cell acute lymphoblastic leukemia. eJHaem 4:1, pages 115-124.
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Merve Kulbay, Adeline Paimboeuf, Derman Ozdemir & Jacques Bernier. (2021) Review of cancer cell resistance mechanisms to apoptosis and actual targeted therapies. Journal of Cellular Biochemistry 123:11, pages 1736-1761.
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Bruna Cristine de Almeida, Laura Gonzalez dos Anjos, Andrey Senos Dobroff, Edmund Chada Baracat, Qiwei Yang, Ayman Al-Hendy & Katia Candido Carvalho. (2022) Epigenetic Features in Uterine Leiomyosarcoma and Endometrial Stromal Sarcomas: An Overview of the Literature. Biomedicines 10:10, pages 2567.
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Merve Kulbay, Bruno Johnson, Guillaume Ricaud, Marie-Noëlle Séguin-Grignon & Jacques Bernier. (2022) Energetic metabolic reprogramming in Jurkat DFF40-deficient cancer cells. Molecular and Cellular Biochemistry 477:9, pages 2213-2233.
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Radmila Sparić, Mladen Andjić, Ivana Babović, Lazar Nejković, Milena Mitrović, Jelena Štulić, Miljan Pupovac & Andrea Tinelli. (2022) Molecular Insights in Uterine Leiomyosarcoma: A Systematic Review. International Journal of Molecular Sciences 23:17, pages 9728.
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Antonio Travaglino, Antonio Raffone, Diego Raimondo, Annarita Gencarelli, Italia Esposito, Cinzia Gallo, Francesco Paolo Improda, Salvatore Giovanni Vitale, Antonio Mollo, Paolo Casadio, Renato Seracchioli, Fulvio Zullo & Luigi Insabato. (2022) Diagnostic and prognostic value of Bcl-2 in uterine leiomyosarcoma. Archives of Gynecology and Obstetrics 307:2, pages 379-386.
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Merve Kulbay, Bruno Johnson, Sophie Fiola, Roberto J. Diaz & Jacques Bernier. (2021) DFF40 deficiency in cancerous T cells is implicated in chemotherapy drug sensitivity and resistance through the regulation of the apoptotic pathway. Biochemical Pharmacology 194, pages 114801.
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Merve Kulbay, Nathan Bernier-Parker & Jacques Bernier. (2021) The role of the DFF40/CAD endonuclease in genomic stability. Apoptosis 26:1-2, pages 9-23.
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Mahdi Barazesh, Shiva Mohammadi, Sajad Jalili, Soudabeh Kavousipour, Seyed Nooreddin Faraji, Pooneh Mokarram & Somayeh Pirhadi. (2021) Design and characterization of a recombinant immunotoxin for targeted therapy of breast cancer cells: In vitro and in silico analyses. Life Sciences 265, pages 118866.
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Merve Kulbay, Bruno Johnson & Jacques Bernier. (2019) DNA fragmentation factor 40 expression in T cells confers sensibility to tributyltin-induced apoptosis. Toxicology 426, pages 152255.
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Mahdi Barazesh, Zohreh Mostafavipour, Soudabeh KavousipourShiva Mohammadi & Pooneh Mokarram. (2019) Two Simple Methods for Optimizing the Production of "Difficult-to-Express" GnRH-DFF40 Chimeric Protein. Advanced Pharmaceutical Bulletin 9:3, pages 423-431.
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Piotr Rubisz, Michał Ciebiera, Lidia Hirnle, Magdalena Zgliczyńska, Tomasz Łoziński, Piotr Dzięgiel & Christopher Kobierzycki. (2019) The Usefulness of Immunohistochemistry in the Differential Diagnosis of Lesions Originating from the Myometrium. International Journal of Molecular Sciences 20:5, pages 1136.
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Tomasz Banas, Kazimierz Pitynski, Krzysztof Okon & Aleksandra Winiarska. (2018) Non-endometrioid and high-grade endometrioid endometrial cancers show DNA fragmentation factor 40 (DFF40) and B-cell lymphoma 2 protein (BCL2) underexpression, which predicts disease-free and overall survival, but not DNA fragmentation factor 45 (DFF45) underexpression. BMC Cancer 18:1.
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