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Original Research

Relationship between HER2 gene status and selected potential biological features related to trastuzumab resistance and its influence on survival of breast cancer patients undergoing trastuzumab adjuvant treatment

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Pages 4525-4535 | Published online: 03 Aug 2018

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Ran Ran, Wenfa Huang, Yaxin Liu, Lin Shao, Xiaoran Liu, Yunyun Niu, Weiyao Kong, Shiping Bo, Hope S Rugo, Sijia Lu & Huiping Li. (2020) Prognostic Value of Plasma HER2 Gene Copy Number in HER2-Positive Metastatic Breast Cancer Treated with First-Line Trastuzumab. OncoTargets and Therapy 13, pages 4385-4395.
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Qitong Wu & Dipali Sharma. (2023) Autophagy and Breast Cancer: Connected in Growth, Progression, and Therapy. Cells 12:8, pages 1156.
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Christopher Y.C. Chow, Erich Ferdiansyah Lie, Cheng-Hsun Wu & Louis W.C. Chow. (2022) Clinical implication of genetic composition and molecular mechanism on treatment strategies of HER2-positive breast cancers. Frontiers in Oncology 12.
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B. R. Nagarjun, Biren Parikh, Manaswi Nareshkumar Patel, Pina J. Trivedi & Dharmesh M. Patel. (2022) Indian Data on HER2 Fluorescence In Situ Hybridization in Invasive Breast Cancer with Immunohistochemically Equivocal Results As Per 2018 ASCO/CAP Guidelines. South Asian Journal of Cancer 11:04, pages 281-286.
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William D. Sinclair & Xiaoyan Cui. (2022) The Effects of HER2 on CDK4/6 Activity in Breast Cancer. Clinical Breast Cancer 22:3, pages e278-e285.
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Alessandro Allegra, Claudia Petrarca, Mario Di Gioacchino, Marco Casciaro, Caterina Musolino & Sebastiano Gangemi. (2022) Exosome-Mediated Therapeutic Strategies for Management of Solid and Hematological Malignancies. Cells 11:7, pages 1128.
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Fahai Chen & Jianmin Fang. (2022) Benefits of Targeted Molecular Therapy to Immune Infiltration and Immune-Related Genes Predicting Signature in Breast Cancer. Frontiers in Oncology 12.
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Yan Liang, Chao Qian, Yinghong Xie, Xiang Huang, Junjie Chen, Yanlin Ren, Ziyi Fu, Yongfei Li, Tianyu Zeng, Fan Yang, Jianwei Zhou, Wei Li, Yongmei Yin & Changqing Wang. (2021) JWA suppresses proliferation in trastuzumab-resistant breast cancer by downregulating CDK12. Cell Death Discovery 7:1.
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Jong-Ho Cheun, Jiyoung Won, Ji Gwang Jung, Hong-Kyu Kim, Wonshik Han & Han-Byoel Lee. (2021) Impact of Trastuzumab on Ipsilateral Breast Tumor Recurrence for Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer after Breast-Conserving Surgery. Journal of Breast Cancer 24:3, pages 301.
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Mingli Han, Yuanting Gu, Pengwei Lu, Jingyi Li, Hui Cao, Xiangke Li, Xueke Qian, Chao Yu, Yunqing Yang, Xue Yang, Na Han, Dongwei Dou, Jianguo Hu & Huaying Dong. (2020) RETRACTED ARTICLE: Exosome-mediated lncRNA AFAP1-AS1 promotes trastuzumab resistance through binding with AUF1 and activating ERBB2 translation. Molecular Cancer 19:1.
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Chundi Gao, Jing Zhuang, Huayao Li, Cun Liu, Chao Zhou, Lijuan Liu, Fubin Feng, Changgang Sun & Jibiao Wu. (2020) Development of a risk scoring system for evaluating the prognosis of patients with Her2-positive breast cancer. Cancer Cell International 20:1.
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Mingli Han, Xueke Qian, Hui Cao, Fang Wang, Xiangke Li, Na Han, Xue Yang, Yunqing Yang, Dongwei Dou, Jianguo Hu, Wei Wang, Jing Han, Fan Zhang & Huaying Dong. (2020) lncRNA ZNF649-AS1 Induces Trastuzumab Resistance by Promoting ATG5 Expression and Autophagy. Molecular Therapy 28:11, pages 2488-2502.
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Albina Stocker, Andreas Trojan, Constanze Elfgen, Marie-Louis Hilbers, Linda Moskovszky & Zsuzsanna Varga. (2020) Differential prognostic value of positive HER2 status determined by immunohistochemistry or fluorescence in situ hybridization in breast cancer. Breast Cancer Research and Treatment 183:2, pages 311-319.
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M. Sorokin, K. Ignatev, V. Barbara, U. Vladimirova, A. Muraveva, M. Suntsova, N. Gaifullin, I. Vorotnikov, D. Kamashev, A. Bondarenko, M. Baranova, E. Poddubskaya & A. Buzdin. (2020) Molecular Pathway Activation Markers Are Associated with Efficacy of Trastuzumab Therapy in Metastatic HER2-Positive Breast Cancer Better than Individual Gene Expression Levels. Biochemistry (Moscow) 85:7, pages 758-772.
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Mingli Han, Jianguo Hu, Pengwei Lu, Hui Cao, Chao Yu, Xiangke Li, Xueke Qian, Xue Yang, Yunqing Yang, Na Han, Dongwei Dou, Fan Zhang, Mulin Ye, Changcheng Yang, Yuanting Gu & Huaying Dong. (2020) Exosome-transmitted miR-567 reverses trastuzumab resistance by inhibiting ATG5 in breast cancer. Cell Death & Disease 11:1.
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Louis W.C. Chow, Erich F. Lie & Masakazu Toi. 2020. Receptor Tyrosine Kinases. Receptor Tyrosine Kinases 375 428 .
Zhi-Hua Liu, Kun Wang, Dan-Yi Lin, Jie Xu, Jie Chen, Xiao-Yu Long, Yan Ge, Xin-Lan Luo, Ke-Ping Zhang, Yan-Hui Liu & Fang-Ping Xu. (2019) Impact of the updated 2018 ASCO/CAP guidelines on HER2 FISH testing in invasive breast cancer: a retrospective study of HER2 fish results of 2233 cases. Breast Cancer Research and Treatment 175:1, pages 51-57.
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Aamir Ahmad. 2019. Breast Cancer Metastasis and Drug Resistance. Breast Cancer Metastasis and Drug Resistance 217 228 .