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OncoTargets and Therapy Volume 11, 2018 - Issue
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Original Research

Radix Tetrastigma hemsleyani flavone exhibits antitumor activity in colorectal cancer via Wnt/β-catenin signaling pathway

Xiaowei Wu1 Department of Gastroenterology and Hepatology, Jinling Hospital, Nanjing, China
,
Na Yu1 Department of Gastroenterology and Hepatology, Jinling Hospital, Nanjing, China
,
Yuping Zhang2 Department of Gastroenterology and Hepatology, Jinling Hospital, Southern Medical University, Guangzhou, China
,
Yuanning Ye2 Department of Gastroenterology and Hepatology, Jinling Hospital, Southern Medical University, Guangzhou, China
,
Wenrong Sun1 Department of Gastroenterology and Hepatology, Jinling Hospital, Nanjing, China
,
Lei Ye1 Department of Gastroenterology and Hepatology, Jinling Hospital, Nanjing, China
,
Huimin Wu3 Department of Gastroenterology and Hepatology, Jinling Hospital, Medical School of Nanjing University, Nanjing, China, [email protected]
,
Zhao Yang2 Department of Gastroenterology and Hepatology, Jinling Hospital, Southern Medical University, Guangzhou, China
,
Lin Wu1 Department of Gastroenterology and Hepatology, Jinling Hospital, Nanjing, China
&
Fangyu Wang3 Department of Gastroenterology and Hepatology, Jinling Hospital, Medical School of Nanjing University, Nanjing, China, [email protected]Correspondence[email protected]
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Pages 6437-6446 | Published online: 04 Oct 2018

Citations (13)

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Yonglu Li, Yaxuan Wang, Xin Yu, Ting Yu, Xiaodong Zheng & Qiang Chu. (2022) Radix Tetrastigma Inhibits the Non-Small Cell Lung Cancer via Bax/Bcl-2/Caspase-9/Caspase-3 Pathway. Nutrition and Cancer 74:1, pages 320-332.
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Zhuonan Pu, Fang Yang, Liang Wang, Yunpeng Diao & Dapeng Chen. (2021) Advancements of compounds targeting Wnt and Notch signalling pathways in the treatment of inflammatory bowel disease and colon cancer. Journal of Drug Targeting 29:5, pages 507-519.
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Articles from other publishers (11)

Bing Han, Yufei Zhai, Xuan Li, Huan Zhao, Chengtao Sun, Yuqing Zeng, Weiping Zhang, Jinjian Lu & Guoyin Kai. (2023) Total flavonoids of Tetrastigma hemsleyanum Diels et Gilg inhibits colorectal tumor growth by modulating gut microbiota and metabolites. Food Chemistry 410, pages 135361.
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Jing Wang, Wen Cao, Tao Ji, Minjie Zhao, Tao Liu, Junhao Wu, Fengqin Feng, Aicun Zhou & Xin Peng. (2023) Gut microbiota and transcriptome profiling revealed the protective effect of aqueous extract of Tetrastigma hemsleyanum leaves on ulcerative colitis in mice. Current Research in Food Science 6, pages 100426.
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Yufei Zhai, Jing Sun, Chengtao Sun, Huan Zhao, Xuan Li, Jiaxiong Yao, Jiajia Su, Xiaoqian Xu, Xiukun Xu, Jiangning Hu, Maria Daglia, Bing Han & Guoyin Kai. (2022) Total flavonoids from the dried root of Tetrastigma hemsleyanum Diels et Gilg inhibit colorectal cancer growth through PI3K / AKT / mTOR signaling pathway . Phytotherapy Research 36:11, pages 4263-4277.
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Yu‐Te Liu, Bor‐Show Tzang, JiaLe Yow, Yi‐Hsuan Chiang, Chih‐Yang Huang & Tsai‐Ching Hsu. (2022) Traditional Chinese medicine formula T33 inhibits the proliferation of human colorectal cancer cells by inducing autophagy . Environmental Toxicology 37:5, pages 1007-1017.
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Shuo Zhang, Tongxing Cui, Yin Duan, Hongchen Zhang, Bei Wang, Huiling Chen, Junjie Ni, Yilin Shen & Xiao-ai Lv. (2022) Radix Tetrastigma Extracts Enhance the Chemosensitivity in Triple-Negative Breast Cancer Via Inhibiting PI3K/Akt/mTOR-Mediated Autophagy. Clinical Breast Cancer 22:2, pages 89-97.
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Jinrong Chang, Hoileong Wong Xavier, Dongfeng Chen, Yamei Liu, Hui Li & Zhaoxiang Bian. (2021) Potential Role of Traditional Chinese Medicines by Wnt/β-Catenin Pathway Compared With Targeted Small Molecules in Colorectal Cancer Therapy. Frontiers in Pharmacology 12.
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Kailong Wang, Qian Chen, Yingying Shao, Shuangshuang Yin, Caiyan Liu, Yiman Liu, Rui Wang, Tao Wang, Yuling Qiu & Haiyang Yu. (2021) Anticancer activities of TCM and their active components against tumor metastasis. Biomedicine & Pharmacotherapy 133, pages 111044.
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Aldona Kasprzak. (2020) Angiogenesis-Related Functions of Wnt Signaling in Colorectal Carcinogenesis. Cancers 12:12, pages 3601.
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Ji‐Na Pak, Ji Hoon Jung, Ji Eon Park, Jisung Hwang, Hyo Jung Lee, Bum‐Sang Shim & Sung‐Hoon Kim. (2020) p53 dependent LGR5 inhibition and caspase 3 activation are critically involved in apoptotic effect of compound K and its combination therapy potential in HCT116 cells . Phytotherapy Research 34:10, pages 2745-2755.
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Ruyi Zhu, Xiaofen Xu, Jialiang Ying, Gang Cao & Xin Wu. (2020) The Phytochemistry, Pharmacology, and Quality Control of Tetrastigma hemsleyanum Diels & Gilg in China: A Review. Frontiers in Pharmacology 11.
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Qiang Chu, Wen Chen, Ruoyi Jia, Xiang Ye, Yonglu Li, Yangyang Liu, Yong Jiang & Xiaodong Zheng. (2020) Tetrastigma hemsleyanum leaves extract against acrylamide-induced toxicity in HepG2 cells and Caenorhabditis elegans. Journal of Hazardous Materials 393, pages 122364.
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