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OncoTargets and Therapy Volume 11, 2018 - Issue

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Original Research

Knockdown of CLDN6 inhibits cell proliferation and migration via PI3K/AKT/mTOR signaling pathway in endometrial carcinoma cell line HEC-1-B

Xia CaoDepartment of Gynaecology, Danyang People’s Hospital of Jiangsu Province, Danyang 212300, Jiangsu Province, China, [email protected]

Guo-Zhao HeDepartment of Gynaecology, Danyang People’s Hospital of Jiangsu Province, Danyang 212300, Jiangsu Province, China, [email protected]Correspondence[email protected]

Pages 6351-6360 | Published online: 01 Oct 2018

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Meng Xing, Bin’e Wu & Shuxia Wang. (2022) Heat Shock Protein B7 Inhibits the Progression of Endometrial Carcinoma by Inhibiting PI3K/AKT/mTOR Pathway. Reproductive Sciences 30:2, pages 590-600.
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Zeina Nehme, Natascha Roehlen, Punita Dhawan & Thomas F. Baumert. (2023) Tight Junction Protein Signaling and Cancer Biology. Cells 12:2, pages 243.
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Huinan Qu, Min Wang, Miaomiao Wang, Yuanyuan Liu & Chengshi Quan. (2022) The expression and the tumor suppressor role of CLDN6 in colon cancer. Molecular and Cellular Biochemistry 477:12, pages 2883-2893.
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Wanjie Wang, Huiying Zou, Nanzhu Chen, Yaqing Tian, Haisheng Hao, Yunwei Pang, Xueming Zhao, Huabin Zhu, Dawei Yu & Weihua Du. (2022) Knockdown of CLAUDIN-6 Inhibited Apoptosis and Induced Proliferation of Bovine Cumulus Cells. International Journal of Molecular Sciences 23:21, pages 13222.
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Huinan Qu, Da Qi, Xinqi Wang, Yuan Dong, Qiu Jin, Junyuan Wei & Chengshi Quan. (2021) CLDN6 Suppresses c–MYC–Mediated Aerobic Glycolysis to Inhibit Proliferation by TAZ in Breast Cancer. International Journal of Molecular Sciences 23:1, pages 129.
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Huinan Qu, Qiu Jin & Chengshi Quan. (2021) CLDN6: From Traditional Barrier Function to Emerging Roles in Cancers. International Journal of Molecular Sciences 22:24, pages 13416.
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Huan Du, Xiyue Yang, Jinjia Fan & Xiaobo Du. (2021) Claudin 6: Therapeutic prospects for tumours, and mechanisms of expression and regulation (Review). Molecular Medicine Reports 24:3.
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Jian Li. (2021) Context-Dependent Roles of Claudins in Tumorigenesis. Frontiers in Oncology 11.
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Manabu Kojima, Kotaro Sugimoto, Mizuko Tanaka, Yuta Endo, Hitomi Kato, Tsuyoshi Honda, Shigenori Furukawa, Hiroshi Nishiyama, Takafumi Watanabe, Shu Soeda, Keiya Fujimori & Hideki Chiba. (2020) Prognostic Significance of Aberrant Claudin-6 Expression in Endometrial Cancer. Cancers 12:10, pages 2748.
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Yun Liu, Yue Chang, Xinhong He, Yixuan Cai, Hao Jiang, Ru Jia & Jiyan Leng. (2020) CD47 Enhances Cell Viability and Migration Ability but Inhibits Apoptosis in Endometrial Carcinoma Cells via the PI3K/Akt/mTOR Signaling Pathway. Frontiers in Oncology 10.
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Lingyuan Huang, Chanjuan Zhao, Kai Sun, Dandan Yang, Linxia Yan, Dan Luo, Jinli He, Xuemei Hu, Rong Wang, Xiaofei Shen, Ning Xiao & Zhendong Zhong. (2020) Downregulation of CLDN6 inhibits cell proliferation, migration, and invasion via regulating EGFR/AKT/mTOR signalling pathway in hepatocellular carcinoma. Cell Biochemistry and Function 38:5, pages 541-548.
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Tomohiro Kohmoto, Kiyoshi Masuda, Katsutoshi Shoda, Rizu Takahashi, Sae Ujiro, Shoichiro Tange, Daisuke Ichikawa, Eigo Otsuji & Issei Imoto. (2019) Claudin-6 is a single prognostic marker and functions as a tumor-promoting gene in a subgroup of intestinal type gastric cancer. Gastric Cancer 23:3, pages 403-417.
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Liheng Liu, Haili Jiang, Xiaoxin Wang, Xin Wang & Liying Zou. (2020) STYX/FBXW7 axis participates in the development of endometrial cancer cell via Notch–mTOR signaling pathway. Bioscience Reports 40:4.
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Marta Justyna Kozieł, Karolina Kowalska & Agnieszka Wanda Piastowska-Ciesielska. (2020) Claudins: New Players in Human Fertility and Reproductive System Cancers. Cancers 12:3, pages 711.
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Kening Zhou, Jian Zhao, Lifang Qi, Yingying He, Jingui Xu & Mimi Dai. (2020) Kinesin Family Member C1 (KIFC1) Accelerates Proliferation and Invasion of Endometrial Cancer Cells Through Modulating the PI3K/AKT Signaling Pathway. Technology in Cancer Research & Treatment 19, pages 153303382096421.
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Cheng Chen, Jiaru Lin, Li Li, Tingting Zhu, Lichao Gao, Weihua Wu, Qi Liu & Santao Ou. (2019) The role of the BMP4/Smad1 signaling pathway in mesangial cell proliferation: A possible mechanism of diabetic nephropathy. Life Sciences 220, pages 106-116.
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Knockdown of CLDN6 inhibits cell proliferation and migration via PI3K/AKT/mTOR signaling pathway in endometrial carcinoma cell line HEC-1-B

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Knockdown of CLDN6 inhibits cell proliferation and migration via PI3K/AKT/mTOR signaling pathway in endometrial carcinoma cell line HEC-1-B

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