A temperature-sensitive phase-change hydrogel of topotecan achieves a long-term sustained antitumor effect on retinoblastoma cells

Yan Huo1 Department of Ophthalmology, The 1st Medical Center Of Chinese PLA General Hospital , Beijing 100853, People’s Republic of China;2 The Institutional Animal Care and Use Committee of National Beijing Center for Drug Safety Assessment, Institute of Pharmacology and Toxicology, Academy of Military Medical Sciences, Beijing 100850, People’s Republic of China

Qun Wang1 Department of Ophthalmology, The 1st Medical Center Of Chinese PLA General Hospital , Beijing 100853, People’s Republic of China

Ying Liu1 Department of Ophthalmology, The 1st Medical Center Of Chinese PLA General Hospital , Beijing 100853, People’s Republic of China

Junyi Wang1 Department of Ophthalmology, The 1st Medical Center Of Chinese PLA General Hospital , Beijing 100853, People’s Republic of China

Qian Li1 Department of Ophthalmology, The 1st Medical Center Of Chinese PLA General Hospital , Beijing 100853, People’s Republic of China

Zongyuan Li1 Department of Ophthalmology, The 1st Medical Center Of Chinese PLA General Hospital , Beijing 100853, People’s Republic of China

Yan Dong1 Department of Ophthalmology, The 1st Medical Center Of Chinese PLA General Hospital , Beijing 100853, People’s Republic of China

Yifei Huang1 Department of Ophthalmology, The 1st Medical Center Of Chinese PLA General Hospital , Beijing 100853, People’s Republic of ChinaCorrespondence[email protected] [email protected]

Liqiang Wang1 Department of Ophthalmology, The 1st Medical Center Of Chinese PLA General Hospital , Beijing 100853, People’s Republic of China

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A temperature-sensitive phase-change hydrogel of topotecan achieves a long-term sustained antitumor effect on retinoblastoma cells

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A temperature-sensitive phase-change hydrogel of topotecan achieves a long-term sustained antitumor effect on retinoblastoma cells

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