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OncoTargets and Therapy Volume 13, 2020 - Issue
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Original Research

Knockdown of FOXO6 Inhibits Glycolysis and Reduces Cell Resistance to Paclitaxel in HCC Cells via PI3K/Akt Signaling Pathway

Xixiang Yu1 Wenzhou Medical University, Wenzhou No. 3 Clinical College, Wenzhou, Zhejiang Province, People’s Republic of China
,
Xixi Gao2 Qingyuan County People’s Hospital, Qingyuan, Zhejiang Province, People’s Republic of China
,
Xiaoping Mao3 The Third Affiliated Hospital of Wenzhou Medical University, Ruian, Zhejiang Province, People’s Republic of China
,
Zhenjing Shi3 The Third Affiliated Hospital of Wenzhou Medical University, Ruian, Zhejiang Province, People’s Republic of China
,
Bangxuan Zhu1 Wenzhou Medical University, Wenzhou No. 3 Clinical College, Wenzhou, Zhejiang Province, People’s Republic of China
,
Linqin Xie1 Wenzhou Medical University, Wenzhou No. 3 Clinical College, Wenzhou, Zhejiang Province, People’s Republic of China
,
Shaodan Di1 Wenzhou Medical University, Wenzhou No. 3 Clinical College, Wenzhou, Zhejiang Province, People’s Republic of China
&
Limin Jin3 The Third Affiliated Hospital of Wenzhou Medical University, Ruian, Zhejiang Province, People’s Republic of ChinaCorrespondence[email protected]
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Pages 1545-1556 | Published online: 19 Feb 2020

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Qiu Chen, Haisen Zhou & Weihao Rong. (2022) Circular RNA_0078767 upregulates Kruppel-like factor 9 expression by targeting microRNA-889, thereby inhibiting the progression of osteosarcoma. Bioengineered 13:6, pages 14313-14328.
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Guanjun Liu, Dongmei Wu, Yiyang Wen & Shundong Cang. (2021) Immune-associated molecular occurrence and prognosis predictor of hepatocellular carcinoma: an integrated analysis of GEO datasets. Bioengineered 12:1, pages 5253-5265.
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Wei Han, Jia Shi, Jiachao Cao, Bo Dong & Wei Guan. (2020) Emerging Roles and Therapeutic Interventions of Aerobic Glycolysis in Glioma. OncoTargets and Therapy 13, pages 6937-6955.
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Articles from other publishers (10)

Guanjie Ji, Yue Li, Zhiyue Zhang, Hui Li & Ping Sun. (2024) Recent advances of novel targeted drug delivery systems based on natural medicine monomers against hepatocellular carcinoma. Heliyon 10:2, pages e24667.
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Sneha Malleswari Poleboyina, Pavan Kumar Poleboyina, Smita C. Pawar & Girijasankar Guntuku. (2023) Homology Modeling, Screening, and Identification of Potential FOXO6 Inhibitors Curtail Gastric Cancer Progression: an In Silico Drug Repurposing Approach. Applied Biochemistry and Biotechnology 195:12, pages 7708-7737.
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Xingxing Zhuang, Tao Liu, Liangbing Wei & Jiarong Gao. (2023) Overexpression of FTO inhibits excessive proliferation and promotes the apoptosis of human glomerular mesangial cells by alleviating FOXO6 m6A modification via YTHDF3-dependent mechanisms. Frontiers in Pharmacology 14.
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Mahshid Deldar Abad Paskeh, Fatemeh Ghadyani, Mehrdad Hashemi, Alireza Abbaspour, Amirhossein Zabolian, Salar Javanshir, Mehrnaz Razzazan, Sepideh Mirzaei, Maliheh Entezari, Mohammad Ali Shekhi Beig Goharrizi, Shokooh Salimimoghadam, Amir Reza Aref, Alireza Kalbasi, Romina Rajabi, Mohsen Rashidi, Afshin Taheriazam & Gautam Sethi. (2023) Biological impact and therapeutic perspective of targeting PI3K/Akt signaling in hepatocellular carcinoma: Promises and Challenges. Pharmacological Research 187, pages 106553.
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Panpan Yin, Jiahui Chen, Yanlin Wu, Feng Gao, Jinlin Wen, Wenbin Zhang, Ying Su & Xinyan Zhang. (2022) Chemoprevention of 4NQO-Induced Mouse Tongue Carcinogenesis by AKT Inhibitor through the MMP-9/RhoC Signaling Pathway and Autophagy. Analytical Cellular Pathology 2022, pages 1-15.
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Chang Liu, Ying Jin & Zhimin Fan. (2021) The Mechanism of Warburg Effect-Induced Chemoresistance in Cancer. Frontiers in Oncology 11.
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Milad Ashrafizadeh, Sepideh Mirzaei, Farid Hashemi, Ali Zarrabi, Amirhossein Zabolian, Hossein Saleki, Seyed Omid Sharifzadeh, Leyla Soleymani, Salman Daneshi, Kiavash Hushmandi, Haroon Khan, Alan Prem Kumar, Amir Reza Aref & Saeed Samarghandian. (2021) New insight towards development of paclitaxel and docetaxel resistance in cancer cells: EMT as a novel molecular mechanism and therapeutic possibilities. Biomedicine & Pharmacotherapy 141, pages 111824.
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Elizabeth R. M. Zunica, Shengping Yang, Ann Coulter, Christy White, John P. Kirwan & Linda A. Gilmore. (2021) Moringa Oleifera Seed Extract Concomitantly Supplemented with Chemotherapy Worsens Tumor Progression in Mice with Triple Negative Breast Cancer and Obesity. Nutrients 13:9, pages 2923.
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Shaojie Yang, Liwei Pang, Wanlin Dai, Shuodong Wu, Tengqi Ren, Yunlong Duan, Yuting Zheng, Shiyuan Bi, Xiaolin Zhang & Jing Kong. (2021) Role of Forkhead Box O Proteins in Hepatocellular Carcinoma Biology and Progression (Review). Frontiers in Oncology 11.
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Fabrizio Marcucci & Cristiano Rumio. (2021) Glycolysis-induced drug resistance in tumors—A response to danger signals?. Neoplasia 23:2, pages 234-245.
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