Near Complete Pathologic Response to PD-1 Inhibitor and Radiotherapy in a Patient with Locally Advanced Pancreatic Ductal Adenocarcinoma

Patrick M McCarthy1 Department of Surgery, Brooke Army Medical Center, San Antonio, TX, USACorrespondence[email protected]

https://orcid.org/0000-0002-8805-8148

Matthew J Rendo2 Department of Hematology and Oncology, Brooke Army Medical Center, San Antonio, TX, USA

Matthew D Uy3 Department of Pathology, Brooke Army Medical Center, San Antonio, TX, USA

Alexandra M Adams1 Department of Surgery, Brooke Army Medical Center, San Antonio, TX, USA

Anne E O’Shea1 Department of Surgery, Brooke Army Medical Center, San Antonio, TX, USA

Daniel William Nelson4 Department of Surgery, William Beaumont Army Medical Center, El Paso, TX, USA

Joshua L Fenderson2 Department of Hematology and Oncology, Brooke Army Medical Center, San Antonio, TX, USA

Katherine M Cebe3 Department of Pathology, Brooke Army Medical Center, San Antonio, TX, USA

Robert W Krell1 Department of Surgery, Brooke Army Medical Center, San Antonio, TX, USA

Guy T Clifton1 Department of Surgery, Brooke Army Medical Center, San Antonio, TX, USA

George E Peoples5 Cancer Vaccine Development Program, San Antonio, TX, USA

https://orcid.org/0000-0001-7118-8205

Timothy J Vreeland1 Department of Surgery, Brooke Army Medical Center, San Antonio, TX, USA

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Tarak Chouari, Francesca Soraya La Costa, Nabeel Merali, Maria-Danae Jessel, Shivan Sivakumar, Nicola Annels & Adam E. Frampton. (2023) Advances in Immunotherapeutics in Pancreatic Ductal Adenocarcinoma. Cancers 15:17, pages 4265.
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Robert Connor Chick, Andrew J. Gunderson, Shafia Rahman & Jordan M. Cloyd. (2023) Neoadjuvant Immunotherapy for Localized Pancreatic Cancer: Challenges and Early Results. Cancers 15:15, pages 3967.
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Marta Fudalej, Daria Kwaśniewska, Paweł Nurzyński, Anna Badowska-Kozakiewicz, Dominika Mękal, Aleksandra Czerw, Katarzyna Sygit & Andrzej Deptała. (2023) New Treatment Options in Metastatic Pancreatic Cancer. Cancers 15:8, pages 2327.
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Juan Du, Changchang Lu, Liang Mao, Yahui Zhu, Weiwei Kong, Shanshan Shen, Min Tang, Shanhua Bao, Hao Cheng, Gang Li, Jun Chen, Qi Li, Jian He, Aimei Li, Xin Qiu, Qing Gu, Dongsheng Chen, Chuang Qi, Yunjie Song, Xiaoping Qian, Lei Wang, Yudong Qiu & Baorui Liu. (2023) PD-1 blockade plus chemoradiotherapy as preoperative therapy for patients with BRPC/LAPC: A biomolecular exploratory, phase II trial. Cell Reports Medicine 4:3, pages 100972.
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Changchang Lu, Yahui Zhu, Hao Cheng, Weiwei Kong, Linxi Zhu, Lei Wang, Min Tang, Jun Chen, Qi Li, Jian He, Aimei Li, Xin Qiu, Dongsheng Chen, Fanyan Meng, Xiaoping Qian, Baorui Liu, Yudong Qiu & Juan Du. (2022) Case Report: Pathologic Complete Response to Induction Therapy in a Patient With Potentially Resectable Pancreatic Cancer. Frontiers in Oncology 12.
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Lingyue Liu, Xing Huang, Fukang Shi, Jinyuan Song, Chengxiang Guo, Jiaqi Yang, Tingbo Liang & Xueli Bai. (2022) Combination therapy for pancreatic cancer: anti-PD-(L)1-based strategy. Journal of Experimental & Clinical Cancer Research 41:1.
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Zhen-Chong Yang, Ting Liu, Yan-Zhou Chen, Chun-Yan Guo, Li-Ting Liu, Sai-Lan Liu, Qiu-Yan Chen, Hai-Qiang Mai & Shan-Shan Guo. (2022) First-Line Immunochemotherapy Versus Palliative Chemotherapy Plus Definitive Radiation Therapy for de novo Metastatic Nasopharyngeal Carcinoma: A Matched Cohort Study . Cancer Control 29, pages 107327482211248.
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Near Complete Pathologic Response to PD-1 Inhibitor and Radiotherapy in a Patient with Locally Advanced Pancreatic Ductal Adenocarcinoma

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Near Complete Pathologic Response to PD-1 Inhibitor and Radiotherapy in a Patient with Locally Advanced Pancreatic Ductal Adenocarcinoma

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