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OncoTargets and Therapy Volume 8, 2015 - Issue
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Original Research

A high LDL-C to HDL-C ratio predicts poor prognosis for initially metastatic colorectal cancer patients with elevations in LDL-C

Fangxin Liao1 State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, People’s Republic of China;2 VIP Region, Sun Yat-sen University Cancer Center, Guangzhou, People’s Republic of China
,
Wenzhuo He1 State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, People’s Republic of China;2 VIP Region, Sun Yat-sen University Cancer Center, Guangzhou, People’s Republic of China
,
Chang Jiang1 State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, People’s Republic of China;2 VIP Region, Sun Yat-sen University Cancer Center, Guangzhou, People’s Republic of China
,
Chenxi Yin1 State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, People’s Republic of China;2 VIP Region, Sun Yat-sen University Cancer Center, Guangzhou, People’s Republic of China
,
Guifang Guo1 State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, People’s Republic of China;2 VIP Region, Sun Yat-sen University Cancer Center, Guangzhou, People’s Republic of China
,
Xuxian Chen1 State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, People’s Republic of China;2 VIP Region, Sun Yat-sen University Cancer Center, Guangzhou, People’s Republic of China
,
Huijuan Qiu1 State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, People’s Republic of China;2 VIP Region, Sun Yat-sen University Cancer Center, Guangzhou, People’s Republic of China
,
Yuming Rong1 State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, People’s Republic of China;2 VIP Region, Sun Yat-sen University Cancer Center, Guangzhou, People’s Republic of China
,
Bei Zhang1 State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, People’s Republic of China;2 VIP Region, Sun Yat-sen University Cancer Center, Guangzhou, People’s Republic of China
,
Dazhi Xu1 State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, People’s Republic of China;3 Gastric and Pancreatic Surgery, Sun Yat-sen University Cancer Center, Guangzhou, People’s Republic of ChinaCorrespondence[email protected]
&
Liangping Xia1 State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, People’s Republic of China;2 VIP Region, Sun Yat-sen University Cancer Center, Guangzhou, People’s Republic of ChinaCorrespondence[email protected]
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Pages 3135-3142 | Published online: 27 Oct 2015

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Bo Hao, Baochen Bi, Chen Sang, Miaomei Yu, Dongmei Di, Guanghua Luo & Xiaoying Zhang. (2019) Systematic Review and Meta-Analysis of the Prognostic Value of Serum High-Density Lipoprotein Cholesterol Levels for Solid Tumors. Nutrition and Cancer 71:4, pages 547-556.
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Articles from other publishers (24)

Meijuan Tan, Shijie Yang & Xiequn Xu. (2023) High-density lipoprotein cholesterol and carcinogenesis. Trends in Endocrinology & Metabolism 34:5, pages 303-313.
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Jiahui Feng, Zhizhong Gong, Zhangran Sun, Juan Li, Na Xu, Rick F. Thorne, Xu Dong Zhang, Xiaoying Liu & Gang Liu. (2023) Microbiome and metabolic features of tissues and feces reveal diagnostic biomarkers for colorectal cancer. Frontiers in Microbiology 14.
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Siyu Zhou, Qian He, Nengquan Sheng, Jianfeng Gong, Jiazi Ren & Zhigang Wang. (2022) Blood cholesterol-to-lymphocyte ratio as a novel prognostic marker to predict postoperative overall survival in patients with colorectal cancer. World Journal of Surgical Oncology 20:1.
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Long Bai, Xiao-Luan Yan, Yun-Xin Lu, Qi Meng, Yu-Ming Rong, Liu-Fang Ye, Zhi-Zhong Pan, Bao-Cai Xing & De-Shen Wang. (2022) Circulating Lipid- and Inflammation-Based Risk (CLIR) Score: A Promising New Model for Predicting Outcomes in Complete Colorectal Liver Metastases Resection. Annals of Surgical Oncology 29:7, pages 4308-4323.
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Kush K. Patel & Khosrow Kashfi. (2022) Lipoproteins and cancer: The role of HDL-C, LDL-C, and cholesterol-lowering drugs. Biochemical Pharmacology 196, pages 114654.
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Yang Geng, Yan Liu, Yan Chen, Zhenwen Zhang, Liping Wang, Xiaobo Li, Binlan Xia, Bin Song & Hengzhong Zhang. (2021) Association of LDLc to HDLc ratio with carotid plaques in a community-based population with a high stroke risk: A cross-sectional study in China. Clinical Biochemistry 88, pages 43-48.
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Łukasz Zadka, Damian J. Grybowski & Piotr Dzięgiel. (2020) Modeling of the immune response in the pathogenesis of solid tumors and its prognostic significance. Cellular Oncology 43:4, pages 539-575.
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Kristen D. Brantley, Anders H. Riis, Rune Erichsen, Ole Thorlacius-Ussing, Holger Jon Møller & Timothy L. Lash. (2020) The association of serum lipid levels with colorectal cancer recurrence. Cancer Epidemiology 66, pages 101725.
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Hao Chen, Ling-Yu Chu, Xiao-Hui Li, Yu-Hui Peng, Can-Tong Liu, Li-Ru Tian, Jian-Jun Xie & Yi-Wei Xu. (2020) ApoB/ApoA-1 Ratio as a Novel Prognostic Predictor in Patients With Primary Small Cell Carcinoma of the Esophagus. Frontiers in Oncology 10.
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Manar F. Alharbi, Ayat B. Al-Ghafari, Huda A. Al Doghaither, Huda F. Alshaibi & Ulfat M. Omar. (2020) Contribution of Apolipoprotein E Isoforms to Colorectal Cancer Carcinogenesis. Pakistan Journal of Biological Sciences 23:3, pages 306-312.
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Malini Visweswaran, Frank Arfuso, Sudha Warrier & Arun Dharmarajan. (2020) Aberrant lipid metabolism as an emerging therapeutic strategy to target cancer stem cells. Stem Cells 38:1, pages 6-14.
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Xin Zhang, Huimin Sun, Wanyuan Chen & Xianglei He. (2019) Elevated expression of AGGF1 predicts poor prognosis and promotes the metastasis of colorectal cancer. BMC Cancer 19:1.
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Daiki Matsubara, Katsutoshi Shoda, Takeshi Kubota, Toshiyuki Kosuga, Hirotaka Konishi, Atsushi Shiozaki, Hitoshi Fujiwara, Kazuma Okamoto, Michihiro Kudou, Tomohiro Arita, Ryo Morimura, Yasutoshi Murayama, Hisashi Ikoma, Yoshiaki Kuriu, Masayoshi Nakanishi & Eigo Otsuji. (2019) Preoperative total cholesterol-lymphocyte score as a novel immunonutritional predictor of survival in gastric cancer. Langenbeck's Archives of Surgery 404:6, pages 743-752.
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Yun Wang, Xiao‐qiang Sun, Hao‐cheng Lin, De‐shen Wang, Zhi‐qiang Wang, Qiong Shao, Feng‐hua Wang, Shu‐mei Yan, Jie‐ying Liang, Zhao‐lei Zeng, Huai‐qiang Ju, Rui‐hua Xu & Yu‐hong Li. (2019) Correlation between immune signature and high‐density lipoprotein cholesterol level in stage II/III colorectal cancer. Cancer Medicine 8:3, pages 1209-1217.
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Marija Mihajlovic, Tamara Gojkovic, Sandra Vladimirov, Milica Miljkovic, Aleksandra Stefanovic, Jelena Vekic, Dejan Zeljkovic, Bratislav Trifunovic, Jelena Kotur-Stevuljevic, Vesna Spasojevic-Kalimanovska & Aleksandra Zeljkovic. (2019) Changes in lecithin: cholesterol acyltransferase, cholesteryl ester transfer protein and paraoxonase-1 activities in patients with colorectal cancer. Clinical Biochemistry 63, pages 32-38.
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Milica Stevanovic, Jelena Vekic, Natasa Bogavac-Stanojevic, Jelena Janac, Zeljka Stjepanovic, Dejan Zeljkovic, Bratislav Trifunovic, Vesna Spasojevic-Kalimanovska & Aleksandra Zeljkovic. (2018) Significance of LDL and HDL subclasses characterization in the assessment of risk for colorectal cancer development. Biochemia Medica 28:3.
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Matteo Pirro, Biagio Ricciuti, Daniel J. Rader, Alberico L. Catapano, Amirhossein Sahebkar & Maciej Banach. (2018) High density lipoprotein cholesterol and cancer: Marker or causative?. Progress in Lipid Research 71, pages 54-69.
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Maria Notarnicola, Dionigi Lorusso, Valeria Tutino, Valentina De Nunzio, Giampiero De Leonardis, Gisella Marangelli, Vito Guerra, Nicola Veronese, Maria Caruso & Gianluigi Giannelli. (2018) Differential Tissue Fatty Acids Profiling between Colorectal Cancer Patients with and without Synchronous Metastasis. International Journal of Molecular Sciences 19:4, pages 962.
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Lu Tian, Qian Yu, Xing-Hui Gao, Jiong Wu, Xiao-Lu Ma, Qian Dai, Chun-Yan Zhang, Yan Zhou, Yi-Chi Zhang, Bai-Shen Pan, Jian Zhou, Jia Fan, Xin-Rong Yang & Wei Guo. (2017) A new use for an old index: preoperative high-density lipoprotein predicts recurrence in patients with hepatocellular carcinoma after curative resections. Lipids in Health and Disease 16:1.
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Ting‐Ting Hong, Di Shen, Xiao‐Ping Chen, Xiao‐Hong Wu & Dong Hua. (2016) Preoperative serum lipid profile and outcome in nonmetastatic colorectal cancer. Chronic Diseases and Translational Medicine 2:4, pages 241-249.
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