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OncoTargets and Therapy Volume 10, 2017 - Issue

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Original Research

Anti-RhoC siRNAs inhibit the proliferation and invasiveness of breast cancer cells via modulating the KAI1, MMP9, and CXCR4 expression

Xu-Dong Xu1 Department of Thyroid and Breast Surgery, The Fifth Hospital of Wuhan, Hanyang District

Han-Bin Shen1 Department of Thyroid and Breast Surgery, The Fifth Hospital of Wuhan, Hanyang District

Li Zhu2 Department of Oncology

Jian-Qin Lu2 Department of Oncology

Lin Zhang3 Department of Thyroid and Breast Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, People’s Republic of China

Zhi-Yong Luo3 Department of Thyroid and Breast Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, People’s Republic of China

Ya-Qun Wu3 Department of Thyroid and Breast Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, People’s Republic of ChinaCorrespondence[email protected]

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Pages 1827-1834 | Published online: 23 Mar 2017

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Mohammad Qasim Andrabi, Ilangovan Ramachandran, R. Ileng Kumaran & Satish Ramalingam. 2023. Handbook of Animal Models and its Uses in Cancer Research. Handbook of Animal Models and its Uses in Cancer Research 875 892 .

Mohammad Qasim Andrabi, Ilangovan Ramachandran, R. Ileng Kumaran & Satish Ramalingam. 2022. Handbook of Animal Models and its Uses in Cancer Research. Handbook of Animal Models and its Uses in Cancer Research 1 18 .

Yingyue Lou, Yuhan Jiang, Zhen Liang, Bingzhang Liu, Tian Li & Duo Zhang. (2021) Role of RhoC in cancer cell migration. Cancer Cell International 21:1.
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G. Sanjeev, S. Pranavkrishna, R.L. Akshaya, M. Rohini & N. Selvamurugan. (2021) Regulation of bone metastasis and metastasis suppressors by non-coding RNAs in breast cancer. Biochimie 187, pages 14-24.
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Khulood M. Al-Khater, Sarah Almofty, Vijaya Ravinayagam, Noor Alrushaid & Suriya Rehman. (2021) Role of a metastatic suppressor gene KAI1/CD82 in the diagnosis and prognosis of breast cancer. Saudi Journal of Biological Sciences 28:6, pages 3391-3398.
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Shokooh Salimimoghadam, Sina Taefehshokr, Reid Loveless, Yong Teng, Gloria Bertoli, Nima Taefehshokr, Fatemeh Musaviaroo, Khalil Hajiasgharzadeh & Behzad Baradaran. (2021) The role of tumor suppressor short non-coding RNAs on breast cancer. Critical Reviews in Oncology/Hematology 158, pages 103210.
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Stephen P. Ethier, Stephen T. Guest, Elizabeth Garrett-Mayer, Kent Armeson, Robert C. Wilson, Kathryn Duchinski, Daniel Couch, Joe W. Gray & Christiana Kappler. (2020) Development and implementation of the SUM breast cancer cell line functional genomics knowledge base. npj Breast Cancer 6:1.
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S. L. Xie, M. Wang, X. H. Du, Z. W. Zhao & G. Y. Lv. (2020) miR-455 Inhibits HepG2 Cell Proliferation and Promotes Apoptosis by Targeting RhoC. Molecular Biology 54:1, pages 59-66.
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Pavana Thomas, Annapurna Pranatharthi, Cecil Ross & Sweta Srivastava. (2019) RhoC: a fascinating journey from a cytoskeletal organizer to a Cancer stem cell therapeutic target. Journal of Experimental & Clinical Cancer Research 38:1.
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Zhihua Zhao, Kai Liu, Xiangyu Tian, Miaomiao Sun, Na Wei, Xiaoyan Zhu, Hongmei Yang, Tong Wang, Guozhong Jiang & Kuisheng Chen. (2019) Effects of RhoC downregulation on the angiogenesis characteristics of myeloma vascular endothelial cells. Cancer Medicine 8:7, pages 3502-3510.
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Ji-Gang Zhang, Dan-Dan Zhang, Ying Liu, Juan-Ni Hu, Xue Zhang, Li Li, Wan Mu, Guan-Hua Zhu, Qin Li & Gao-Lin Liu. (2019) RhoC/ROCK2 promotes vasculogenic mimicry formation primarily through ERK/MMPs in hepatocellular carcinoma. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1865:6, pages 1113-1125.
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Shweta Jain, Kamla Pathak & Ankur Vaidya. (2018) Molecular therapy using siRNA: Recent trends and advances of multi target inhibition of cancer growth. International Journal of Biological Macromolecules 116, pages 880-892.
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Eirini Nomikou, Melina Livitsanou, Christos Stournaras & Dimitris Kardassis. (2018) Transcriptional and post-transcriptional regulation of the genes encoding the small GTPases RhoA, RhoB, and RhoC: implications for the pathogenesis of human diseases. Cellular and Molecular Life Sciences 75:12, pages 2111-2124.
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Md. Karim, Kyi Tha, Iekhsan Othman, Mohammad Borhan Uddin & Ezharul Chowdhury. (2018) Therapeutic Potency of Nanoformulations of siRNAs and shRNAs in Animal Models of Cancers. Pharmaceutics 10:2, pages 65.
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Marzia Dolcino, Andrea Pelosi, Piera Filomena Fiore, Giuseppe Patuzzo, Elisa Tinazzi, Claudio Lunardi & Antonio Puccetti. (2018) Gene Profiling in Patients with Systemic Sclerosis Reveals the Presence of Oncogenic Gene Signatures. Frontiers in Immunology 9.
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Y Lu, T Qin, J Li, L Wang, Q Zhang, Z Jiang & J Mao. (2017) MicroRNA-140-5p inhibits invasion and angiogenesis through targeting VEGF-A in breast cancer. Cancer Gene Therapy 24:9, pages 386-392.
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Teresa P. Raposo, Hugo Arias-Pulido, Nabila Chaher, Steven N. Fiering, David J. Argyle, Justina Prada, Isabel Pires & Felisbina Luísa Queiroga. (2017) Comparative aspects of canine and human inflammatory breast cancer. Seminars in Oncology 44:4, pages 288-300.
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Anti-RhoC siRNAs inhibit the proliferation and invasiveness of breast cancer cells via modulating the KAI1, MMP9, and CXCR4 expression

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Anti-RhoC siRNAs inhibit the proliferation and invasiveness of breast cancer cells via modulating the KAI1, MMP9, and CXCR4 expression

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