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Review

CYP3A5 polymorphisms in renal transplant recipients: influence on tacrolimus treatment

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Pages 23-33 | Published online: 07 Mar 2018

Keep up to date with the latest research on this topic with citation updates for this article.

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Yuyao Peng, Fei Jiang, Ran Zhou, Wanlin Jin, Yi Li, Weiwei Duan, Liqun Xu & Huan Yang. (2021) Clinical Evaluation of the Efficacy and Safety of Co-Administration of Wuzhi Capsule and Tacrolimus in Adult Chinese Patients with Myasthenia Gravis. Neuropsychiatric Disease and Treatment 17, pages 2281-2289.
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Mersedeh Shayan & Sepideh Elyasi. (2020) Cilastatin as a protective agent against drug-induced nephrotoxicity: a literature review. Expert Opinion on Drug Safety 19:8, pages 999-1010.
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Articles from other publishers (16)

Sadaf Firasat, Ali Raza, Abdul Rafay Khan & Aiysha Abid. (2023) The prevalence of pharmacogenetic variants of vitamin K epoxide reductase complex subunit 1 gene (rs9923231), cytochrome P450 family 2 subfamily C member 9 gene (rs1799853) and cytochrome P450 family 3 subfamily-A member-5 gene (rs776746) among 13 ethnic groups of Pakistan. Molecular Biology Reports 50:5, pages 4017-4027.
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K.I. Bentsionova, Z.I. Rossokha, O.G. Ievseienkova & N.G. Gorovenko. (2023) Pharmacogenetic substantiation of personalized prescription of oral anticoagulants in clinical practice. Medicni perspektivi 28:1, pages 55-68.
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Jinhua Wen, ChenYang, Menghua Zhao, Weiqiang Hu & Yu Wei Xiao. (2023) Effects of clarithromycin on the pharmacokinetics of tacrolimus and expression of CYP3A4 and P‐glycoprotein in rats. Fundamental & Clinical Pharmacology.
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Fang Cheng, Qiang Li, Zheng Cui, Zhendi Wang, Fang Zeng & Yu Zhang. (2022) Tacrolimus Concentration Is Effectively Predicted Using Combined Clinical and Genetic Factors in the Perioperative Period of Kidney Transplantation and Associated with Acute Rejection. Journal of Immunology Research 2022, pages 1-8.
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Hisham A. Edinur, Siti Nor A. Mat-Ghani & Geoffrey K. Chambers. (2022) Ethnicity-based classifications and medical genetics: One Health approaches from a Western Pacific perspective. Frontiers in Genetics 13.
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Karla Escobar Castro & Armando Caceres. (2021) Influencia del polimorfismo de CYP3A4 y CYP3A5 en la farmacocinética de tacrolimus en receptores de trasplante renal. Revisión narrativa. Ciencia, Tecnologí­a y Salud 8:2, pages 220-231.
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Lekshmy Srinivas, Noble Gracious & Radhakrishnan R. Nair. (2021) Pharmacogenetics Based Dose Prediction Model for Initial Tacrolimus Dosing in Renal Transplant Recipients. Frontiers in Pharmacology 12.
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Jingheng Wang, Cameron D. Buchman, Jayaraman Seetharaman, Darcie J. Miller, Andrew D. Huber, Jing Wu, Sergio C. Chai, Efren Garcia-Maldonado, William C. Wright, Jude Chenge & Taosheng Chen. (2021) Unraveling the Structural Basis of Selective Inhibition of Human Cytochrome P450 3A5. Journal of the American Chemical Society 143:44, pages 18467-18480.
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Chieri Fujino, Seigo Sanoh & Toshiya Katsura. (2021) Variation in Expression of Cytochrome P450 3A Isoforms and Toxicological Effects: Endo- and Exogenous Substances as Regulatory Factors and Substrates. Biological and Pharmaceutical Bulletin 44:11, pages 1617-1634.
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Janaína B. F. Everton, Fernando J. B. Patrício, Manuel S. Faria, Teresa C. A. Ferreira, Elen A. Romao, Gyl E. B. Silva & Marcelo Magalhães. (2021) CYP3A5 and PPARA genetic variants are associated with low trough concentration to dose ratio of tacrolimus in kidney transplant recipients. European Journal of Clinical Pharmacology 77:6, pages 879-886.
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Jorge E. B. da Rocha, Houcemeddine Othman, Gerrit Botha, Laura Cottino, David Twesigomwe, Samah Ahmed, Britt I. Drögemöller, Faisal M. Fadlelmola, Philip Machanick, Mamana Mbiyavanga, Sumir Panji, Galen E. B. Wright, Clement Adebamowo, Mogomotsi Matshaba, Michéle Ramsay, Gustave Simo, Martin C. Simuunza, Caroline T. Tiemessen, Sandra Baldwin, Mathias Chiano, Charles Cox, Annette S. Gross, Pamela Thomas, Francisco-Javier Gamo & Scott Hazelhurst. (2021) The Extent and Impact of Variation in ADME Genes in Sub-Saharan African Populations. Frontiers in Pharmacology 12.
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Jong Man Kim, Je Ho Ryu, Kwang-Woong Lee, Suk Kyun Hong, Kwangho Yang, Gyu-Seong Choi, Young-Ae Kim, Ju-Yeun Lee, Nam-Joon Yi, Choon Hyuck David Kwon, Chong Woo Chu, Kyung-Suk Suh & Jae-Won Joh. (2020) Effect of CYP3A5 on the Once-Daily Tacrolimus Conversion in Stable Liver Transplant Patients. Journal of Clinical Medicine 9:9, pages 2897.
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Effrosyni Mendrinou, Mohamed Elsayed Mashaly, Amir Mohamed Al Okily, Mohamed Elsayed Mohamed, Ayman Fathi Refaie, Essam Mahmoud Elsawy, Hazem Hamed Saleh, Hussein Sheashaa & George P. Patrinos. (2020) CYP3A5 Gene-Guided Tacrolimus Treatment of Living-Donor Egyptian Kidney Transplanted Patients. Frontiers in Pharmacology 11.
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Mengyu Zhang, Soichiro Tajima, Tomohiro Shigematsu, Rao Fu, Hiroshi Noguchi, Keizo Kaku, Akihiro Tsuchimoto, Yasuhiro Okabe, Nobuaki Egashira & Satohiro Masuda. (2020) Donor CYP3A5 Gene Polymorphism Alone Cannot Predict Tacrolimus Intrarenal Concentration in Renal Transplant Recipients. International Journal of Molecular Sciences 21:8, pages 2976.
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Cordula Stillhart, Katarina Vučićević, Patrick Augustijns, Abdul W. Basit, Hannah Batchelor, Talia R. Flanagan, Ina Gesquiere, Rick Greupink, Daniel Keszthelyi, Mikko Koskinen, Christine M. Madla, Christophe Matthys, Goran Miljuš, Miriam G. Mooij, Neil Parrott, Anna-Lena Ungell, Saskia N. de Wildt, Mine Orlu, Sandra Klein & Anette Müllertz. (2020) Impact of gastrointestinal physiology on drug absorption in special populations––An UNGAP review. European Journal of Pharmaceutical Sciences 147, pages 105280.
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L. Allegri, F. Baldan, C. Vallone, P. Tulissi, M. Gropuzzo, M.F. Canelles, E. Righi, G.L. Adani, U. Baccarani, D. Montanaro, A. Risaliti, G. Damante & M. Baraldo. (2019) Tacrolimus Therapeutic Drug Monitoring in Stable Kidney Transplantation and Individuation of CYP3A5 Genotype. Transplantation Proceedings 51:9, pages 2917-2920.
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