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Pharmacogenomics and Personalized Medicine Volume 9, 2016 - Issue
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Original Research

The correlation between CYP2D6 isoenzyme activity and haloperidol efficacy and safety profile in patients with alcohol addiction during the exacerbation of the addiction

Dmitry Alekseevich Sychev1 Russian Medical Academy of Postgraduate Education, Ministry of Health of the Russian Federation
,
Mikhail Sergeevich Zastrozhin1 Russian Medical Academy of Postgraduate Education, Ministry of Health of the Russian Federation;2 Department of Public Health, Moscow Research and Practical Centre for Narcology;3 Peoples’ Friendship University of RussiaCorrespondence[email protected]
,
Valery Valerieevich Smirnov4 National Research Center, Institute of Immunology Federal Medical-Biological Agency of Russia, Moscow, Russia
,
Elena Anatolievna Grishina1 Russian Medical Academy of Postgraduate Education, Ministry of Health of the Russian Federation
,
Ludmila Mikhailovna Savchenko1 Russian Medical Academy of Postgraduate Education, Ministry of Health of the Russian Federation
&
Evgeny Alekseevich Bryun1 Russian Medical Academy of Postgraduate Education, Ministry of Health of the Russian Federation;2 Department of Public Health, Moscow Research and Practical Centre for Narcology
Pages 89-95 | Published online: 14 Sep 2016

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Mikhail Sergeevich Zastrozhin, Elena Anatolievna Grishina, Kristina Anatolievna Ryzhikova, Valery Valerievich Smirnov, Ludmila Mikhailovna Savchenko, Evgeny Alekseevich Bryun & Dmitry Alekseevich Sychev. (2018) The influence of CYP3A5 polymorphisms on haloperidol treatment in patients with alcohol addiction. Pharmacogenomics and Personalized Medicine 11, pages 1-5.
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Mikhail Sergeevich Zastrozhin, Vadim Markovich Brodyansky, Valentin Yurievich Skryabin, Elena Anatolievna Grishina, Dmitry Vladimirovich Ivashchenko, Kristina Anatolievna Ryzhikova, Ludmila Mikhaylovna Savchenko, Alexander Olegovich Kibitov, Evgeny Alekseevich Bryun & Dmitry Alekseevich Sychev. (2017) Pharmacodynamic genetic polymorphisms affect adverse drug reactions of haloperidol in patients with alcohol-use disorder. Pharmacogenomics and Personalized Medicine 10, pages 209-215.
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Articles from other publishers (8)

Valentin Skryabin, Mikhail Zastrozhin, Alexandra Parkhomenko, Volker M. Lauschke, Valery Smirnov, Aleksey Petukhov, Elena Pankratenko, Sergei Pozdnyakov, Sergei Koporov, Natalia Denisenko, Kristina Akmalova, Evgeny Bryun & Dmitry Sychev. (2022) Genetic Testing is Superior Over Endogenous Pharmacometabolomic Markers to Predict Safety of Haloperidol in Patients with Alcohol-induced Psychotic Disorder. Current Drug Metabolism 23:13, pages 1067-1071.
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Aleksandra Aleksandrovna Parkhomenko, Mikhail Sergeevich Zastrozhin, Valentin Yurievich Skryabin, Lyudmila Mikhailovna Savchenko, Evgeniy Alekseevich Brun, Dmitriy Alekseevich Sychev, Alisher Akhmedovich Yusupov, Vladislav Vladimirovich Alekseyuk & Ani Arturovna Muradyan. (2021) Personalized approach to the administration of haloperidol in patients with acute alcoholic hallucinatie (literature review). Vestnik nevrologii, psihiatrii i nejrohirurgii (Bulletin of Neurology, Psychiatry and Neurosurgery):8, pages 628-638.
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D. A. Sychev & L. K. Moshetova. (2020) Problems of integrating medical science, image and practical health care: focus on personalized medicine. Pharmacogenetics and Pharmacogenomics:1, pages 3-10.
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Mikhail Zastrozhin, Valentin Skryabin, Kristina Ryzhikova & Dmitriy Sychev. (2020) Assessment of the impact of the steady state level of microRNA hsa-miR-370-3p concentration on the efficacy and safety profile of fluvoxamine in patients with depressive disorders disorder comorbid with alcohol use disorders. Vestnik nevrologii, psihiatrii i nejrohirurgii (Bulletin of Neurology, Psychiatry and Neurosurgery):2, pages 37-46.
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Michael S Zastrozhin, Valentin Y Skryabin, Marco Torrado, Anastasiya Petrovna, Alexander S Sorokin, Elena A Grishina, Kristina A Ryzhikova, Inessa A Bedina, Oleg Z Buzik, Egor M Chumakov, Ludmila M Savchenko, Evgeny A Brun & Dmitry A Sychev. (2020) Effects of CYP2C19*2 polymorphisms on the efficacy and safety of phenazepam in patients with anxiety disorder and comorbid alcohol use disorder . Pharmacogenomics 21:2, pages 111-123.
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M.S. ZastrozhinV.Y. SkryabinV.V. SmirnovE.A. GrishinaK.A. RyzhikovaE.M. ChumakovE.A. BryunD.A. Sychev. (2019) Effects of CYP2D6 activity on the efficacy and safety of mirtazapine in patients with depressive disorders and comorbid alcohol use disorder. Canadian Journal of Physiology and Pharmacology 97:8, pages 781-785.
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Mikhail S. Zastrozhin, Valery V. Smirnov, Alexander S. Sorokin, Elena A. Grishina, Kristina A. Ryzhikova, Valery V. Shipitsyn, Ludmila M. Savchenko, Oleg Z. Buzik, Sergey S. Koporov, Evgeny A. Bryun & Dmitry A. Sychev. (2019) The Effect of Cyp2d6 Gene Polymorphism on the Efficacy and Safety of Mirtazapine in Patients with Depressive Disorders Comorbid with Alcohol. Annals of the Russian academy of medical sciences 74:3, pages 185-191.
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Mikhail S. Zastrozhin, Valery V. Smirnov, Alexander S. Sorokin, Elena A. Grishina, Kristina A. Ryzhikova, Inessa A. Bedina, Valery V. Shipitsyn, Ludmila M. Savchenko, Oleg Zh. Buzik, Sergey S. Koporov, Evgeny А. Bryun & Dmitry A. Sychev. (2018) Influence of CYP3A Activity on the Efficacy and Safety of Fluvoxamine in Patients Depressive Disorders and Comorbid Alcohol Use Disorder. Annals of the Russian academy of medical sciences 73:6, pages 411-419.
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