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Pharmacogenomics and Personalized Medicine Volume 10, 2017 - Issue
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Original Research

Pharmacodynamic genetic polymorphisms affect adverse drug reactions of haloperidol in patients with alcohol-use disorder

Mikhail Sergeevich Zastrozhin1 Department of Addictology, Russian Medical Academy of Continuous Professional Education of the Ministry of Health of the Russian Federation, Moscow, Russia;2 Moscow Research and Practical Centre on Addictions of the Moscow Department of Healthcare, Center for the Prevention of Dependent Behavior, Moscow, RussiaCorrespondence[email protected]
,
Vadim Markovich Brodyansky3 Federal Medical Research Centre of Psychiatry and Addictology, Laboratory of Molecular Genetics, Moscow, Russia
,
Valentin Yurievich Skryabin4 Moscow Research and Practical Centre on Addictions of the Moscow Department of Healthcare, Department of Addictology, Moscow, Russia
,
Elena Anatolievna Grishina5 Russian Medical Academy of Continuous Professional Education of the Ministry of Health of the Russian Federation, Research Centre, Moscow, Russia
,
Dmitry Vladimirovich Ivashchenko5 Russian Medical Academy of Continuous Professional Education of the Ministry of Health of the Russian Federation, Research Centre, Moscow, Russia
,
Kristina Anatolievna Ryzhikova5 Russian Medical Academy of Continuous Professional Education of the Ministry of Health of the Russian Federation, Research Centre, Moscow, Russia
,
Ludmila Mikhaylovna Savchenko1 Department of Addictology, Russian Medical Academy of Continuous Professional Education of the Ministry of Health of the Russian Federation, Moscow, Russia
,
Alexander Olegovich Kibitov3 Federal Medical Research Centre of Psychiatry and Addictology, Laboratory of Molecular Genetics, Moscow, Russia
,
Evgeny Alekseevich Bryun1 Department of Addictology, Russian Medical Academy of Continuous Professional Education of the Ministry of Health of the Russian Federation, Moscow, Russia;4 Moscow Research and Practical Centre on Addictions of the Moscow Department of Healthcare, Department of Addictology, Moscow, Russia
&
Dmitry Alekseevich Sychev6 Russian Medical Academy of Continuous Professional Education of the Ministry of Health of the Russian Federation, Department of Clinical Pharmacology and Therapy, Moscow, Russia
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Pages 209-215 | Published online: 07 Jul 2017

Citations (8)

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Ramón Cacabelos, Natalia Cacabelos & Juan C. Carril. (2019) The role of pharmacogenomics in adverse drug reactions. Expert Review of Clinical Pharmacology 12:5, pages 407-442.
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Articles from other publishers (7)

Andrey Alexandrovitch Kibitov, Elena Mikhaylovna Kiryanova, Ludmila Ivanovna Salnikova, Irina Vladimirovna Bure, Alexander Borisovitch Shmukler & Alexander Olegovitch Kibitov. (2022) The ANKK1/DRD2 gene TaqIA polymorphism (rs1800497) is associated with the severity of extrapyramidal side effects of haloperidol treatment in CYP2D6 extensive metabolizers with schizophrenia spectrum disorders. Drug Metabolism and Personalized Therapy 0:0.
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Chuang-Wei Wang, Ivan Arni C. Preclaro, Wei-Hsiang Lin & Wen-Hung Chung. (2022) An Updated Review of Genetic Associations With Severe Adverse Drug Reactions: Translation and Implementation of Pharmacogenomic Testing in Clinical Practice. Frontiers in Pharmacology 13.
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D. A. Sychev & L. K. Moshetova. (2020) Problems of integrating medical science, image and practical health care: focus on personalized medicine. Pharmacogenetics and Pharmacogenomics:1, pages 3-10.
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Valentin Yu Skryabin, Mikhail S. Zastrozhin, Marco V. Torrado, Elena A. Grishina, Kristina A. Ryzhikova, Valery V. Shipitsyn, Tatiana E. Galaktionova, Alexander S. Sorokin, Evgeny A. Bryun & Dmitry A. Sychev. (2020) How do CYP2C19*2 and CYP2C19*17 genetic polymorphisms affect the efficacy and safety of diazepam in patients with alcohol withdrawal syndrome?. Drug Metabolism and Personalized Therapy 0:0.
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Zhimei Fu, Bingwei Hu, Tingting Ma, Qiandong Wang & Dongdong Wang. (2020) Effect of ADRA2A gene polymorphisms on the anesthetic and analgesic effects of dexmedetomidine in Chinese Han women with cesarean section. Experimental and Therapeutic Medicine.
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V. Yu. Skryabin, M. S. Zastrozhin, E. A. Grishina, K. A. Ryzhikova, V. V. Shipitsyn, I. V. Barna, T. E. Galaktionova, A. S. Sorokin, E. A. Bryun & D. A. Sychev. (2020) The relationship between the CYP2C19*17 genetic polymorphism and the efficacy and safety of diazepam in patients with alcohol withdrawal syndrome. Bulletin of Siberian Medicine 18:4, pages 119-126.
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M.S. ZastrozhinV.Y. SkryabinV.V. SmirnovE.A. GrishinaK.A. RyzhikovaE.M. ChumakovE.A. BryunD.A. Sychev. (2019) Effects of CYP2D6 activity on the efficacy and safety of mirtazapine in patients with depressive disorders and comorbid alcohol use disorder. Canadian Journal of Physiology and Pharmacology 97:8, pages 781-785.
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