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Original Research

ABCB1 haplotype and OPRM1 118A > G genotype interaction in methadone maintenance treatment pharmacogenetics

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Pages 53-62 | Published online: 18 Apr 2012

Keep up to date with the latest research on this topic with citation updates for this article.

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Ahmad Akbari, Ali Kheradmand, Marzie Sina, Abolhassan Ahmadiani & Sareh Asadi. (2021) OPRM1 and CYP3A4 association with methadone dose in Iranian patients undergoing methadone maintenance therapy. Journal of Addictive Diseases 39:3, pages 357-362.
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Henrike Bruckmueller & Ingolf Cascorbi. (2021) ABCB1, ABCG2, ABCC1, ABCC2, and ABCC3 drug transporter polymorphisms and their impact on drug bioavailability: what is our current understanding?. Expert Opinion on Drug Metabolism & Toxicology 17:4, pages 369-396.
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Marta Rodríguez-Arias, María A Aguilar & José Miñarro. (2015) Therapies in early development for the treatment of opiate addiction. Expert Opinion on Investigational Drugs 24:11, pages 1459-1472.
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Articles from other publishers (19)

Xiaohu Xie, Jun Gu, Dingding Zhuang, Yun Zhou, Xiaoyu Chen, Wenwen Shen, Longhui Li, Yue Liu, Wenjin Xu, Qingxiao Hong, Zemin Xu, Weisheng Chen, Wenhua Zhou & Huifen Liu. (2022) Association between rs1799971 in the mu opioid receptor gene and methadone maintenance treatment response. Journal of Clinical Laboratory Analysis 36:11.
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Firzana Firfirey, Alison V September & Delva Shamley. (2022) ABCB1 and OPRM1 single-nucleotide polymorphisms collectively modulate chronic shoulder pain and dysfunction in South African breast cancer survivors . Pharmacogenomics 23:9, pages 513-530.
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Blessed W. Aruldhas, Sara K. Quinney, Brian R. Overholser, Michael A. Heathman, Andrea R. Masters, Reynold C. Ly, Hongyu Gao, Senthil Packiasabapathy & Senthilkumar Sadhasivam. (2021) Pharmacokinetic modeling of R and S‐Methadone and their metabolites to study the effects of various covariates in post‐operative children. CPT: Pharmacometrics & Systems Pharmacology 10:10, pages 1183-1194.
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Luke Rowsell, Justin Guang‐Ao Wu, Brendon J. Yee, Keith K.H. Wong, Sheila Sivam, Andrew A. Somogyi, Ronald R. Grunstein & David Wang. (2020) The effect of acute morphine on sleep in male patients suffering from sleep apnea: Is there a genetic effect? An RCT Study. Journal of Sleep Research 30:4.
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S. Iwersen-Bergmann, S. Plattner, S. Hischke, A. Müller, H. Andresen-Streichert, H. Jungen, R. Erb & B. Beer-Sandner. (2021) Brain/blood ratios of methadone and ABCB1 polymorphisms in methadone-related deaths. International Journal of Legal Medicine 135:2, pages 473-482.
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Senthil Packiasabapathy, Blessed W Aruldhas, Nicole Horn, Brian R Overholser, Sara K Quinney, Janelle S Renschler & Senthilkumar Sadhasivam. (2020) Pharmacogenomics of methadone: a narrative review of the literature. Pharmacogenomics 21:12, pages 871-887.
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Maria Carmen Blanco-Gandía, Sandra Montagud-Romero & Marta Rodríguez-Arias. 2020. Opioids - From Analgesic Use to Addiction. Opioids - From Analgesic Use to Addiction.
Eva Montanari, Maria Paola Bonasoni, Federica Alessandrini, Raffaele Frazzi, Federico Mocchegiani, Francesco Paolo Busardò, Raffaele Giorgetti & Adriano Tagliabracci. (2019) CYP2B6, ABCB1 and OPRM1 profile in a stillborn affected by chronic methadone intoxication. Forensic Toxicology 37:2, pages 507-516.
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Sufang Peng, Haifeng Jiang, Jiang Du, Shuxing Lin, Shujun Pan, Shunying Yu & Min Zhao. (2018) Methadone Dosage and Plasma Levels, SNPs of OPRM1 Gene and Age of First Drug Use Were Associated With Outcomes of Methadone Maintenance Treatment. Frontiers in Genetics 9.
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Bilel Oueslati, Olfa Moula & Rim Ghachem. (2018) The impact of OPRM1 's genetic polymorphisms on methadone maintenance treatment in opioid addicts: a systematic review . Pharmacogenomics 19:8, pages 741-747.
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Rui Luo, Xingyuan Li, Shasha Qin, Zhenzhou Luo, Xi Luo, Peiwu Hu, Zhisheng Liu, Xiangling Feng & Xingli Li. (2017) Impact of SNP–SNP interaction among ABCB1 , ARRB2 , DRD1 and OPRD1 on methadone dosage requirement in Han Chinese patients . Pharmacogenomics 18:18, pages 1659-1670.
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Cynthia Marie-ClaireClément Jourdaine, Jean-Pierre Lépine, Frank Bellivier, Vanessa BlochFlorence Vorspan. (2017) Pharmacoepigenomics of opiates and methadone maintenance treatment: current data and perspectives. Pharmacogenomics 18:14, pages 1359-1372.
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Cynthia Marie-Claire, Severine Crettol, Nicolas Cagnard, Vanessa Bloch, Stéphane Mouly, Jean-Louis Laplanche, Frank Bellivier, Jean-Pierre Lepine, Chin Eap & Florence Vorspan. (2016) Variability of response to methadone: genome-wide DNA methylation analysis in two independent cohorts. Epigenomics 8:2, pages 181-195.
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Yu-Li Liu, Jieh-Hen Tsung, Chiu-Ping Fang, Sheng-Wen Liu, Chien-Wen Lai, Chieh-Liang Huang & Sheng-Chang Wang. 2016. Neuropathology of Drug Addictions and Substance Misuse. Neuropathology of Drug Addictions and Substance Misuse 532 541 .
S Sadhasivam, V Chidambaran, X Zhang, J Meller, H Esslinger, K Zhang, L J Martin & J McAuliffe. (2014) Opioid-induced respiratory depression: ABCB1 transporter pharmacogenetics. The Pharmacogenomics Journal 15:2, pages 119-126.
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. 2015. Arzneimitteltherapie in der Palliativmedizin. Arzneimitteltherapie in der Palliativmedizin 863 966 .
Andrew A Somogyi, Daniel T Barratt, Robert L Ali & Janet K Coller. (2014) Pharmacogenomics of methadone maintenance treatment. Pharmacogenomics 15:7, pages 1007-1027.
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David A. Nielsen, Ellen M. Nielsen, Teja Dasari & Catherine J. Spellicy. 2014. Pharmacogenomics in Drug Discovery and Development. Pharmacogenomics in Drug Discovery and Development 589 624 .
Orna LevranEinat Peles, Matthew Randesi, Xu Shu, Jurg Ott, Pei-Hong Shen, Miriam Adelson & Mary Jeanne Kreek. (2013) Association of genetic variation in pharmacodynamic factors with methadone dose required for effective treatment of opioid addiction. Pharmacogenomics 14:7, pages 755-768.
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