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Original Research

Outpatient treatment of low-risk venous thromboembolism with monotherapy oral anticoagulation: patient quality of life outcomes and clinician acceptance

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Pages 561-569 | Published online: 15 Apr 2016

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (2)

William B. Stubblefield & Jeffrey A. Kline. (2021) Outpatient treatment of emergency department patients diagnosed with venous thromboembolism. Postgraduate Medicine 133:sup1, pages 11-19.
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Christopher Kabrhel, Rachel Rosovsky, Christopher Baugh, Blair Alden Parry, Erin Deadmon, Charlotte Kreger & Nicholas Giordano. (2017) The creation and implementation of an outpatient pulmonary embolism treatment protocol. Hospital Practice 45:3, pages 123-129.
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Articles from other publishers (35)

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Ioannis T. Farmakis, Karsten Keller, Stefano Barco, Stavros V. Konstantinides & Lukas Hobohm. (2023) From acute pulmonary embolism to post-pulmonary embolism sequelae. Vasa 52:1, pages 29-37.
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Hugo HB Yoo, Vania Santos Nunes-Nogueira, Paulo J Fortes Villas Boas & Cathryn Broderick. (2022) Outpatient versus inpatient treatment for acute pulmonary embolism. Cochrane Database of Systematic Reviews 2022:5.
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Anouk van de Brug, Maria A. de Winter, Marije ten Wolde, Karin Kaasjager & Mathilde Nijkeuter. (2021) Deciding on Treatment Duration for Unprovoked Venous Thromboembolism: What is Important to Patients?. Thrombosis and Haemostasis 122:04, pages 600-610.
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Lauren K Stewart & Jeffrey A Kline. (2022) Acceptability of Exercise in Urban Emergency Department Patients With Metabolic Syndrome, Including a Subset With Venous Thromboembolism. Journal of Patient Experience 9, pages 237437352210831.
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Jackeline Hernandez‐Nino, Mary Thomas, Andreia B. Alexander, Mary A. Ott & Jeffrey A. Kline. (2022) Communication at diagnosis of venous thromboembolism: Lasting impact of verbal and nonverbal provider communication on patients. Research and Practice in Thrombosis and Haemostasis 6:1, pages e12647.
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Christopher Kabrhel, David R. Vinson, Alice Marina Mitchell, Rachel P. Rosovsky, Anna Marie Chang, Jackeline Hernandez‐Nino & Stephen J. Wolf. (2021) A clinical decision framework to guide the outpatient treatment of emergency department patients diagnosed with acute pulmonary embolism or deep vein thrombosis: Results from a multidisciplinary consensus panel. Journal of the American College of Emergency Physicians Open 2:6.
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Justine Pagenhardt, Isaac Hayward, Brian Dilcher, Kimberly Quedado & Jeffrey Kline. (2021) Incidence of abnormal uterine bleeding in a multicenter implementation study using apixaban and rivaroxaban to treat venous thromboembolism. Thrombosis Research 204, pages 29-31.
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Jeffrey A. Kline, David H. Adler, Naomi Alanis, Joseph R. Bledsoe, Daniel M. CourtneyJames P. d’EtienneDeborah B. Diercks, John S. Garrett, Alan E. JonesDavid C. MackenzieTroy Madsen, Andrew J. Matuskowitz, Bryn E. MummaKristen E. Nordenholz, Justine Pagenhardt, Michael S. RunyonWilliam B. Stubblefield & Christopher B. Willoughby. (2021) Monotherapy Anticoagulation to Expedite Home Treatment of Patients Diagnosed With Venous Thromboembolism in the Emergency Department: A Pragmatic Effectiveness Trial. Circulation: Cardiovascular Quality and Outcomes 14:7.
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Shaina E. Musco, Shannon M. Smallwood & Jill Gossard. (2019) Development and Evaluation of a Pharmacist-Driven Screening Tool to Identify Patients Presenting to the Emergency Department Who Are Eligible for Outpatient Treatment of Deep Vein Thrombosis. Journal of Pharmacy Practice 34:3, pages 378-385.
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Jeffrey A. Kline & Jackeline Hernandez-Nino. (2021) Quality of Life 3 and 12 Months After Acute Pulmonary Embolism. Chest 159:6, pages 2153-2155.
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Adesola Adedeji, Onyinye Chukwura, Taiye Obafemi, Stephen B. McNulty & Justin P. Reinert. (2020) Anticoagulation Strategies in the Management of Lemierre Syndrome: A Systematic Review of the Literature. Annals of Pharmacotherapy 55:5, pages 658-665.
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David R. Vinson, Dustin G. Mark & Dustin W. Ballard. (2021) Overcoming barriers to outpatient management of emergency department patients with acute pulmonary embolism. Academic Emergency Medicine 28:3, pages 377-378.
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Brandon C. Maughan, Lisa Frueh, Marian S. McDonagh, Bryan Casciere & Jeffrey A. Kline. (2020) Outpatient Treatment of Low‐risk Pulmonary Embolism in the Era of Direct Oral Anticoagulants: A Systematic Review. Academic Emergency Medicine 28:2, pages 226-239.
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Jeffrey Kline, David Adler, Naomi Alanis, Joseph Bledsoe, Daniel Courtney, James D'Etienne, Deborah B Diercks, John Garrett, Alan E Jones, David MacKenzie, Troy Madsen, Andrew Matuskowitz, Bryn Mumma, Kristen Nordenholz, Justine Pagenhardt, Michael Runyon, William Stubblefield & Christopher Willoughby. (2020) Study protocol for a multicentre implementation trial of monotherapy anticoagulation to expedite home treatment of patients diagnosed with venous thromboembolism in the emergency department. BMJ Open 10:10, pages e038078.
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Laura E. Simon, Mamata V. Kene, E. Margaret Warton, Adina S. Rauchwerger, David R. Vinson, Mary E. Reed, Uli K. Chettipally, Dustin G. Mark, Dana R. Sax, D. Ian McLachlan, Dale M. Cotton, James S. Lin, Gabriela Vazquez‐Benitez, Anupam B. Kharbanda, Elyse O. Kharbanda & Dustin W. Ballard. (2020) Diagnostic Performance of Emergency Physician Gestalt for Predicting Acute Appendicitis in Patients Age 5 to 20 Years. Academic Emergency Medicine 27:9, pages 821-831.
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Evan Mitchell Tomkiewicz & Jeffery Allen Kline. (2020) Concise Review of the Clinical Approach to the Exclusion and Diagnosis of Pulmonary Embolism in 2020. Journal of Emergency Nursing 46:4, pages 527-538.
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V. V. Boyko, V. A. Prasol, D. V. Oklei & I. A. Taraban. (2019) CLINICAL EFFICACY AND SAFETY OF OUTPATIENT TREATMENT OF PATIENTS WITH DEEP VEIN THROMBOSIS OF THE LOWER EXTREMITIES.. Kharkiv Surgical School:3-4, pages 72-76.
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W. Frank Peacock & Ada.J. Singer. (2019) Reducing the hospital burden associated with the treatment of pulmonary embolism. Journal of Thrombosis and Haemostasis 17:5, pages 720-736.
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Carlos Andrés Quezada, Behnood Bikdeli, Tomás Villén, Deisy Barrios, Edwin Mercedes, Francisco León, Diana Chiluiza, Esther Barbero, Roger D. Yusen & David Jimenez. (2018) Accuracy and Interobserver Reliability of the Simplified Pulmonary Embolism Severity Index Versus the Hestia Criteria for Patients With Pulmonary Embolism. Academic Emergency Medicine 26:4, pages 394-401.
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Hugo HB Yoo, Vania Santos Nunes-Nogueira, Paulo J Fortes Villas Boas & Cathryn Broderick. (2019) Outpatient versus inpatient treatment for acute pulmonary embolism. Cochrane Database of Systematic Reviews.
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Lodewijk C.S. Res, Bart Lubberts, Shivesh H. Shah & Christopher W. DiGiovanni. (2019) Health-related quality of life after adverse bleeding events associated with antithrombotic drug therapy – A systematic review. Hellenic Journal of Cardiology 60:1, pages 3-10.
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Erin R. Weeda & Sofia Butt. (2018) Systematic Review of Real-World Studies Evaluating Characteristics Associated With or Programs Designed to Facilitate Outpatient Management of Deep Vein Thrombosis. Clinical and Applied Thrombosis/Hemostasis 24:9_suppl, pages 301S-313S.
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LJJ Scheres, MPA Brekelmans, W Ageno, C Ay, HR Büller, S Eichinger, BA Hutten, FA Klok, S Middeldorp, K Schreiber, K Stach, M Blondon & A Delluc. (2018) Abnormal vaginal bleeding in women of reproductive age treated with edoxaban or warfarin for venous thromboembolism: a post hoc analysis of the Hokusai-VTE study. BJOG: An International Journal of Obstetrics & Gynaecology 125:12, pages 1581-1589.
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Laura Simon, Hilary Iskin, Ridhima Vemula, Jie Huang, Adina Rauchwerger, Mary Reed, Dustin Ballard & David Vinson. (2018) Emergency Department Patient Satisfaction with Treatment of Low-risk Pulmonary Embolism. Western Journal of Emergency Medicine 19:6, pages 938-946.
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Joseph R. Bledsoe, Scott C. Woller, Scott M. Stevens, Valerie Aston, Rich Patten, Todd Allen, Benjamin D. Horne, Lydia Dong, James Lloyd, Greg Snow, Troy Madsen & C. Gregory Elliott. (2018) Management of Low-Risk Pulmonary Embolism Patients Without Hospitalization. Chest 154:2, pages 249-256.
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Richard Godin, Geneviève Roy & James Douketis. (2018) An opinion on the benefits of concomitant oral contraceptive therapy in premenopausal women treated with oral anticoagulants. Thrombosis Research 165, pages 14-17.
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Stephen J. Wolf, Sigrid A. Hahn, Lauren M. Nentwich, Ali S. Raja, Scott M. Silvers & Michael D. Brown. (2018) Clinical Policy: Critical Issues in the Evaluation and Management of Adult Patients Presenting to the Emergency Department With Suspected Acute Venous Thromboembolic Disease. Annals of Emergency Medicine 71:5, pages e59-e109.
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Lara Nicole Goldstein & Ming-Tung Wu. (2018) A one year audit of patients with venous thromboembolism presenting to a tertiary hospital in Johannesburg, South Africa. African Journal of Emergency Medicine 8:1, pages 12-15.
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Bing Liu, MingYuan Liu, LiHong Yan, JunWei Yan, Jiang Wu, XueFei Jiao & MingJin Guo. (2017) Percutaneous mechanical thrombectomy combined with catheter-directed thrombolysis in the treatment of acute pulmonary embolism and lower extremity deep venous thrombosis: A novel one-stop endovascular strategy. Journal of International Medical Research 46:2, pages 836-851.
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Elizabeth G. Zdyb, D. Mark Courtney, Sanjeev Malik, Michael J. Schmidt & Abbie E. Lyden. (2017) Impact of Discharge Anticoagulation Education by Emergency Department Pharmacists at a Tertiary Academic Medical Center. The Journal of Emergency Medicine 53:6, pages 896-903.
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Aileen Chu & Jill Limberg. (2017) Rivaroxaban program for acute venous thromboembolism upon ED discharge, with focus on utility of commercially available dose pack. The American Journal of Emergency Medicine 35:12, pages 1910-1914.
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Richard Godin, Violaine Marcoux & Vicky Tagalakis. (2017) Abnormal uterine bleeding in women receiving direct oral anticoagulants for the treatment of venous thromboembolism. Vascular Pharmacology 93-95, pages 1-5.
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