598
Views
70
CrossRef citations to date
0
Altmetric
Review

Primary nonadherence to chronic disease medications: a meta-analysis

, , &
Pages 721-731 | Published online: 07 May 2018

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (4)

Orla C. Sheehan, Mandip S. Dhamoon, Janet Prvu Bettger, Jin Huang, Chelsea Liu, J. David Rhodes, Olivio J. Clay & David L. Roth. (2022) Racial differences in persistence to secondary prevention medication regimens after ischemic stroke. Ethnicity & Health 27:7, pages 1671-1683.
Read now
Emilia Montagna, Paola Zagami, Marianna Masiero, Ketti Mazzocco, Gabriella Pravettoni & Elisabetta Munzone. (2021) Assessing Predictors of Tamoxifen Nonadherence in Patients with Early Breast Cancer. Patient Preference and Adherence 15, pages 2051-2061.
Read now
Stephen A. Brunton & Carol H. Wysham. (2020) GLP-1 receptor agonists in the treatment of type 2 diabetes: role and clinical experience to date. Postgraduate Medicine 132:sup2, pages 3-14.
Read now

Articles from other publishers (66)

Chen Yang, Diana Tze Fan Lee & Sek Ying Chair. (2023) Validation and adaption of an Information-Motivation-Behavioral Skills model of medication adherence in older patients with multimorbidity. Patient Education and Counseling 113, pages 107756.
Crossref
Akancha Pandey, Rubesh Raja, Jeremie H. Estepp & Doraiswami Ramkrishna. (2023) Leveraging mathematical modeling to analyze nonadherence for hydroxyurea therapy in sickle cell disease. CPT: Pharmacometrics & Systems Pharmacology 12:6, pages 748-757.
Crossref
Martin Schulz & Ulrich Laufs. (2023) Not obtaining a medication the first time it is prescribed: primary non-adherence to cardiovascular pharmacotherapy. Clinical Research in Cardiology.
Crossref
Matthew T. Mefford, Matt Zhou, Hui Zhou, Hananeh Derakhshan, Teresa N. Harrison, Mona Zia, Michael H. Kanter, Ronald D. Scott, Tracy M. Imley, Mark A. Sanders, Royann Timmins & Kristi Reynolds. (2023) Safety Net Program to Improve Statin Initiation Among Adults With High Low-Density Lipoprotein Cholesterol. American Journal of Preventive Medicine.
Crossref
Edel T O'Hagan, Daniel McIntyre, Tu Nguyen & Clara K Chow. (2023) Hypertension therapy using fixed-dose polypills that contain at least three medications. Heart, pages heartjnl-2022-321496.
Crossref
Minjee Kim, Mary J Kwasny, Stacy C Bailey, Julia Y Benavente, Pauline Zheng, Morgan Bonham, Han Q Luu, Patrick Cecil, Prophecy Agyare, Rachel O'Conor, Laura M Curtis, Scott Hur, Fangyu Yeh, Rebecca M Lovett, Andrea Russell, Yuan Luo, Phyllis C Zee & Michael S Wolf. (2023) MidCog study: a prospective, observational cohort study investigating health literacy, self-management skills and cognitive function in middle-aged adults. BMJ Open 13:2, pages e071899.
Crossref
Nancy Haff, Niteesh K. Choudhry, Thomas Isaac, Gauri Bhatkhande, Cynthia A. Jackevicius, Michael A. Fischer, Daniel H. Solomon, Thomas D. Sequist & Julie C. Lauffenburger. (2023) Disagreement between pharmacy claims and direct interview to identify patients with non-adherence to chronic cardiometabolic medications. American Heart Journal 256, pages 51-59.
Crossref
Danya H. Wilson, Leanne J. Rein, Michele Fountain, Andrea Brookhart, Daniel Atchley & Kenneth C. Hohmeier. (2023) A Pilot Study Exploring the Impact of a Primary Medication Non-Adherence Intervention among Four Chronic Disease States in One Regional Division of a Large Community Pharmacy Chain. Pharmacy 11:1, pages 11.
Crossref
Joel E. Pacyna, Jackson S. Ennis, Iftikhar J. Kullo & Richard R. Sharp. (2023) Examining the Impact of Polygenic Risk Information in Primary Care. Journal of Primary Care & Community Health 14, pages 215013192311517.
Crossref
Mirjam Hempenius, Simone Rijken, Rolf H. H. Groenwold, Karin Hek, Anthonius de Boer, Olaf H. Klungel & Helga Gardarsdottir. (2022) Primary nonadherence to drugs prescribed by general practitioners: A Dutch database study. British Journal of Clinical Pharmacology 89:1, pages 268-278.
Crossref
Carmen Corral-Partearroyo, Alba Sánchez-Viñas, Montserrat Gil-Girbau, María Teresa Peñarrubia-María, Ignacio Aznar-Lou, Antoni Serrano-Blanco, Cristina Carbonell-Duacastella, Carmen Gallardo-González, Maria del Carmen Olmos-Palenzuela & Maria Rubio-Valera. (2022) Improving Initial Medication Adherence to cardiovascular disease and diabetes treatments in primary care: Pilot trial of a complex intervention. Frontiers in Public Health 10.
Crossref
Alba Sánchez-Viñas, Carmen Corral-Partearroyo, Montserrat Gil-Girbau, M. Teresa Peñarrubia-María, Carmen Gallardo-González, María-del-Carmen Olmos-Palenzuela, Ignacio Aznar-Lou, Antoni Serrano-Blanco & Maria Rubio-Valera. (2022) Effectiveness and cost-effectiveness of an intervention to improve Initial Medication Adherence to treatments for cardiovascular diseases and diabetes in primary care: study protocol for a pragmatic cluster randomised controlled trial and economic model (the IMA-cRCT study). BMC Primary Care 23:1.
Crossref
Daria V. Troshina, Denis A. Andreev, Anastasia V. Fomicheva, Alexey N. Volovchenko & Beatrice A. Volel. (2022) Social and psychological risk factors for decreased adherence among patients with atrial fibrillation. Terapevticheskii arkhiv 94:10, pages 1197-1203.
Crossref
Kalsoom Akhter, Stephen Sutton, Venus Mirzaei & Aikaterini Kassavou. (2022) A Systematic Review and Meta-analysis of Face-to-face Medication Adherence Interventions for Patients with Long Term Health Conditions. Annals of Behavioral Medicine 56:12, pages 1218-1230.
Crossref
Xiaowei Yan, Satish Mudiganti, Hannah Husby, Andrew Hudnut, Madina Gbotoe & J. B. Jones. (2022) Medication non-adherence and therapeutic inertia independently contribute to poor disease control for cardiometabolic diseases. Scientific Reports 12:1.
Crossref
Katarzyna Grzyb, Martyna Meresińska, Urszula Religioni, Grzegorz Juszczyk, Jakub Płaczek, Agnieszka Neumann-Podczaska, Filip M. Szymański, Beata Chełstowska, Katarzyna Wieczorowska-Tobis, Szczepan Cofta, Sławomir Tobis, Rafał Staszewski, Regis Vaillancourt, Rafał Majewski, Justyna Hernik, Katarina Fehir Sola, Eliza Blicharska, Justyna Kaźmierczak, Ewa Rutkowska, Elżbieta Prygiel, Monika Skierska, Monika Nawara, Izabela Korbiewska, Jerzy Krysiński & Piotr Merks. (2022) Implementation of the Patient Counselling Service at the Cancer Hospital in Radom, Poland. International Journal of Environmental Research and Public Health 19:20, pages 13642.
Crossref
Seyedeh Farzaneh Mousavi, Maryam Peimani, Sahar Saeedi Moghaddam, Ozra Tabatabaei-Malazy, Erfan Ghasemi, Parnian Shobeiri, Negar Rezaei, Ensieh Nasli-Esfahani & Bagher Larijani. (2022) National and subnational survey on diabetes burden and quality of care index in Iran: a systematic analysis of the global burden of disease study 1990–2019. Journal of Diabetes & Metabolic Disorders 21:2, pages 1599-1608.
Crossref
Carmen Corral-Partearroyo, Alba Sánchez-Viñas, Montserrat Gil-Girbau, Maria Teresa Peñarrubia-María, Ignacio Aznar-Lou, Carmen Gallardo-González, María del Carmen Olmos-Palenzuela & Maria Rubio-Valera. (2022) Complex multidisciplinary intervention to improve Initial Medication Adherence to cardiovascular disease and diabetes treatments in primary care (the IMA-cRCT study): mixed-methods process evaluation protocol. BMJ Open 12:10, pages e067468.
Crossref
Neal J. David, Graham Bresick, Natasha Moodaley & Klaus B. Von Pressentin. (2022) Measuring the impact of community-based interventions on type 2 diabetes control during the COVID-19 pandemic in Cape Town – A mixed methods study. South African Family Practice 64:1.
Crossref
Jessica C. Young, Nabarun Dasgupta, Til Stürmer, Virginia Pate & Michele Jonsson Funk. (2022) Considerations for observational study design: Comparing the evidence of opioid use between electronic health records and insurance claims. Pharmacoepidemiology and Drug Safety 31:8, pages 913-920.
Crossref
Jessica El Halabi, William Minteer & Kasey R. Boehmer. (2022) Identifying and Managing Treatment Nonadherence. Medical Clinics of North America 106:4, pages 615-626.
Crossref
Ana M Gutierrez-Colina, Sara E Wetter, Constance A Mara, Shanna Guilfoyle & Avani C Modi. (2022) Racial Disparities in Medication Adherence Barriers: Pediatric Epilepsy as an Exemplar. Journal of Pediatric Psychology 47:6, pages 620-630.
Crossref
Kadi Lubi, Ain Raal & Pille Taba. (2021) Ethnic Identity in Transition: the Potential Impact of Ethnicity on Chronic Illness’ Medication Adherence in Post-Soviet Country. Journal of Racial and Ethnic Health Disparities 9:3, pages 1089-1095.
Crossref
Hui Zhang, Tao Huang & Tao Yan. (2021) A quantitative analysis of risk-sharing agreements with patient support programs for improving medication adherence. Health Care Management Science 25:2, pages 253-274.
Crossref
Tiziano Lucchi. 2022. Pathy's Principles and Practice of Geriatric Medicine. Pathy's Principles and Practice of Geriatric Medicine 400 418 .
Tiziano LUCCHI. (2022) Dyslipidemia and prevention of atherosclerotic cardiovascular disease in the elderly. Minerva Medica 112:6.
Crossref
Carol Rovira, Pilar Modamio, Joaquim Pascual, Joan Armengol, Cristian Ayala, Joan Gallego, Eduardo L Mariño & Anna Ramirez. (2022) Person-centred care provided by a multidisciplinary primary care team to improve therapeutic adequacy in polymedicated elderly patients (PCMR): randomised controlled trial protocol. BMJ Open 12:2, pages e051238.
Crossref
Cristina Carbonell-Duacastella, Maria Rubio-Valera, Sílvia Marqués-Ercilla, Maria Teresa Peñarrubia-María, Montserrat Gil-Girbau, Victoria Garcia-Cardenas, Maria Isabel Pasarín, Elizabeth Parody-Rúa & Ignacio Aznar-Lou. (2022) Pediatric Medication Noninitiation in Spain. Pediatrics 149:1.
Crossref
Niteesh K. Choudhry, Ian M. Kronish, Wanpen Vongpatanasin, Keith C. Ferdinand, Valory N. Pavlik, Brent M. Egan, Antoinette Schoenthaler, Nancy Houston Miller & David J. Hyman. (2022) Medication Adherence and Blood Pressure Control: A Scientific Statement From the American Heart Association. Hypertension 79:1.
Crossref
Maria Teresa Peñarrubia‐María, Montserrat Gil‐Girbau, Mari Carmen Gallardo‐González, Ignacio Aznar‐Lou, Antoni Serrano‐Blanco, Juan Manuel Mendive Arbeloa, Victoria Garcia‐Cardenas, Alba Sánchez‐Viñas & Maria Rubio‐Valera. (2021) Non‐initiation of prescribed medication from a Spanish health professionals' perspective: A qualitative exploration based on Grounded Theory. Health & Social Care in the Community 30:1.
Crossref
Ruth Jeminiwa, Natalie S. Hohmann, Tessa J. Hastings, Richard Hansen, Jingjing Qian & Kimberly B. Garza. (2022) Individuals’ preference for financial over social incentives for medication adherence. Journal of the American Pharmacists Association 62:1, pages 134-141.e1.
Crossref
Guillaume Fontaine & Sylvie Cossette. (2021) A theory-based adaptive E-learning program aimed at increasing intentions to provide brief behavior change counseling: Randomized controlled trial. Nurse Education Today 107, pages 105112.
Crossref
Bayu Begashaw Bekele, Biruk Bogale, Samuel Negash, Melkamsew Tesfaye, Dawit Getachew, Fekede Weldekidan & Tewodros Yosef. (2021) Public health interventions on prescription redemptions and secondary medication adherence among type 2 diabetes patients: systematic review and meta-analysis of randomized controlled trials. Journal of Diabetes & Metabolic Disorders 20:2, pages 1933-1956.
Crossref
Baojuan Ma, Fengyan Zhang & Baoling Ma. (2021) Self-Attention-Guided Recurrent Neural Network and Motion Perception for Intelligent Prediction of Chronic Diseases. Journal of Healthcare Engineering 2021, pages 1-7.
Crossref
Alberto Alvarez‐Perea, Ves Dimov, Florin‐Dan Popescu & José Manuel Zubeldia. (2021) The applications of eHealth technologies in the management of asthma and allergic diseases. Clinical and Translational Allergy 11:7.
Crossref
Scott HowellPerry T. YinJames C. Robinson. (2021) Quantifying The Economic Burden Of Drug Utilization Management On Payers, Manufacturers, Physicians, And Patients. Health Affairs 40:8, pages 1206-1214.
Crossref
Bettina Habib, David Buckeridge, Melissa Bustillo, Santiago Nicolas Marquez, Manish Thakur, Thai Tran, Daniala L Weir & Robyn Tamblyn. (2021) Smart About Meds (SAM): a pilot randomized controlled trial of a mobile application to improve medication adherence following hospital discharge. JAMIA Open 4:3.
Crossref
Braulio Omar Manzo, Jose David Cabrera, Esteban Emiliani, Hector Manuel Sánchez, Brian Howard Eisner & Jose Ernesto Torres. (2021) Impact of the adherence to medical treatment on the main urinary metabolic disorders in patients with kidney stones. Asian Journal of Urology 8:3, pages 275-279.
Crossref
Derjung M. Tarn, Mark J. Pletcher, Rosa Tosqui, Alicia Fernandez, Chi-hong Tseng, Rachel Moriconi, Douglas S. Bell, Maureen Barrientos, Jon A. Turner & Janice B. Schwartz. (2021) Primary nonadherence to statin medications: Survey of patient perspectives. Preventive Medicine Reports 22, pages 101357.
Crossref
Ana Padilla López, Manuel Alós-Almiñana & José E. Peris. (2020) Health Outcomes and Primary Adherence to Secondary Prevention Treatment after St-Elevation Myocardial Infarction: a Spanish Cohort Study. Journal of Cardiovascular Translational Research 14:2, pages 308-316.
Crossref
Marsha Meyer, Susan Enguidanos, Yujun Zhu, Denise Likar & Romilla Batra. (2020) Community Medication Education, Data, & Safety ( C‐MEDS ): Findings from a Pilot Project . Journal of the American Geriatrics Society 69:3, pages 813-821.
Crossref
Yu.A. Agafonova, D.V. Fedyaev, V.V. Omelyanovskiy & A.V. Snegovoy. (2021) Continuity of outpatient and inpatient drug supply of cancer patients — problems and solutions. Medical Technologies. Assessment and Choice:3, pages 37.
Crossref
Sabina M. De Geest, Janette Ribaut, Kris Denhaerynck & Fabienne Dobbels. 2021. Psychosocial Aspects of Chronic Kidney Disease. Psychosocial Aspects of Chronic Kidney Disease 409 448 .
Grzegorz Kardas, Michał Panek, Piotr Kuna & Przemysław Kardas. (2020) Primary non-adherence to inhaled medications measured with e-prescription data from Poland. Clinical and Translational Allergy 10:1.
Crossref
Mette Friberg Hitz, Sofie Arup, Jakob Praest Holm, Anne Lyngholm Soerensen, Thomas Alexander Gerds & Jens-Erik Beck Jensen. (2020) Outcome of osteoporosis evaluation, treatment, and follow-up in patients referred to a specialized outpatient clinic compared to patients in care of general practitioners. Archives of Osteoporosis 15:1.
Crossref
Johann Kim T. Manez. (2020) Lifestyle Medicine Philippines: A Journey of Hope. American Journal of Lifestyle Medicine 14:6, pages 615-617.
Crossref
Cristina Carbonell-Duacastella, M.ª Montserrat Gil-Girbau, M.ª Teresa Peñarrubia-María, Maria Rubio-Valera & Ignacio Aznar-Lou. (2020) Pacientes no iniciadores de tratamientos. FMC - Formación Médica Continuada en Atención Primaria 27:9, pages 476-479.
Crossref
Nicolò Granata, Silvia Traversoni, Przemysław Kardas, Marta Kurczewska-Michalak, Elísio Costa, Luís Midão & Anna Giardini. (2020) Methodological features of quantitative studies on medication adherence in older patients with chronic morbidity: A systematic review. Patient Education and Counseling 103:10, pages 2132-2141.
Crossref
Frederik Peters, Thea Kreutzburg, Henrik C. Rieß, Franziska Heidemann, Ursula Marschall, Helmut L'Hoest, Eike S. Debus, Art Sedrakyan & Christian-Alexander Behrendt. (2020) Editor's Choice – Optimal Pharmacological Treatment of Symptomatic Peripheral Arterial Occlusive Disease and Evidence of Female Patient Disadvantage: An Analysis of Health Insurance Claims Data. European Journal of Vascular and Endovascular Surgery 60:3, pages 421-429.
Crossref
Gordon Chu, Jaap Seelig, Emmy M Trinks-Roerdink, Anouk P van Alem, Marco Alings, Bart van den Bemt, Lucas VA Boersma, Marc A Brouwer, Suzanne C Cannegieter, Hugo ten Cate, Charles JHJ Kirchhof, Harry JGM Crijns, Ewoud J van Dijk, Arif Elvan, Isabelle C van Gelder, Joris R de Groot, Frank R den Hartog, Jonas SSG de Jong, Sylvie de Jong, Frederikus A Klok, Timo Lenderink, Justin G Luermans, Joan G Meeder, Ron Pisters, Peter Polak, Michiel Rienstra, Frans Smeets, Giovanni JM Tahapary, Luc Theunissen, Robert G Tieleman, Serge A Trines, Pepijn van der Voort, Geert-Jan Geersing, Frans H Rutten, Martin EW Hemels & Menno V Huisman. (2020) Design and rationale of DUTCH-AF: a prospective nationwide registry programme and observational study on long-term oral antithrombotic treatment in patients with atrial fibrillation. BMJ Open 10:8, pages e036220.
Crossref
Khine Swe & S. Sethu K. Reddy. (2020) Improving Adherence in Type 2 Diabetes. Clinics in Geriatric Medicine 36:3, pages 477-489.
Crossref
G. Chu, J. Seelig, E. M. Trinks-Roerdink, G. J. Geersing, F. H. Rutten, J. R. de Groot, M. V. Huisman & M. E. W. Hemels. (2020) Antithrombotic management of patients with atrial fibrillation—Dutch anticoagulant initiatives anno 2020. Netherlands Heart Journal 28:S1, pages 19-24.
Crossref
Nicola Di Trani, Antonia Silvestri, Yu Wang, Danilo Demarchi, Xuewu Liu & Alessandro Grattoni. (2020) Silicon Nanofluidic Membrane for Electrostatic Control of Drugs and Analytes Elution. Pharmaceutics 12:7, pages 679.
Crossref
M. Maffoni, S. Traversoni, E. Costa, L. Midão, P. Kardas, M. Kurczewska-Michalak & A. Giardini. (2020) Medication adherence in the older adults with chronic multimorbidity: a systematic review of qualitative studies on patient’s experience. European Geriatric Medicine 11:3, pages 369-381.
Crossref
M. Gil-Girbau, I. Aznar-Lou, M.T. Peñarrubia-María, P. Moreno-Peral, A. Fernández, J.Á. Bellón, A.M. Jové, J. Mendive, R. Fernández-Vergel, A. Figueiras, M. March-Pujol & M. Rubio-Valera. (2020) Reasons for medication non-initiation: A qualitative exploration of the patients’ perspective. Research in Social and Administrative Pharmacy 16:5, pages 663-672.
Crossref
Chen Yang, Zhaozhao Hui, Dejian Zeng, Li Liu & Diana Tze Fan Lee. (2020) Examining and adapting the information–motivation–behavioural skills model of medication adherence among community-dwelling older patients with multimorbidity: protocol for a cross-sectional study. BMJ Open 10:3, pages e033431.
Crossref
Om J. Lakhani & Surender Kumar. (2020) The Achilles heel of chronic disorders – Medication adherence. Current Medicine Research and Practice 10:2, pages 39-40.
Crossref
Heather Hoch De Keyser, Rachelle Ramsey & Monica J. Federico. (2020) They just don't take their medicines: Reframing medication adherence in asthma from frustration to opportunity. Pediatric Pulmonology 55:3, pages 818-825.
Crossref
Elizabeth Parody-Rúa, Maria Rubio-Valera, César Guevara-Cuellar, Ainhoa Gómez-Lumbreras, Marc Casajuana-Closas, Cristina Carbonell-Duacastella & Ignacio Aznar-Lou. (2020) Economic Evaluations Informed Exclusively by Real World Data: A Systematic Review. International Journal of Environmental Research and Public Health 17:4, pages 1171.
Crossref
Marie Carole Boucher, Hamza Ouazani Chahdi & Mohammed El Mehdi El Yamani. (2020) Compliance to follow-up care after urban diabetic retinopathy tele-screening. Canadian Journal of Ophthalmology 55:1, pages 2-7.
Crossref
Tejas Kamat. (2020) Digital therapeutics can improve medication adherence in diabetes. Journal of Family Medicine and Primary Care 9:11, pages 5806.
Crossref
Amitava Banerjee, Valerio Benedetto, Philip Gichuru, Jane Burnell, Sotiris Antoniou, Richard J Schilling, William David Strain, Ronan Ryan, Caroline Watkins, Tom Marshall & Chris J Sutton. (2020) Adherence and persistence to direct oral anticoagulants in atrial fibrillation: a population-based study. Heart 106:2, pages 119-126.
Crossref
Nouh Harsha, László Kőrösi, Anita Pálinkás, Klára Bíró, Klára Boruzs, Róza Ádány, János Sándor & Árpád Czifra. (2019) Determinants of Primary Nonadherence to Medications Prescribed by General Practitioners Among Adults in Hungary: Cross-Sectional Evaluation of Health Insurance Data. Frontiers in Pharmacology 10.
Crossref
Saurav Ghimire, Kenneth Lee, Matthew D. Jose, Ronald L. Castelino & Syed Tabish R. Zaidi. (2019) Adherence assessment practices in haemodialysis settings: A qualitative exploration of nurses and pharmacists' perspectives. Journal of Clinical Nursing 28:11-12, pages 2197-2205.
Crossref
McVin Hua Heng Cheen, Yan Zhi Tan, Ling Fen Oh, Hwee Lin Wee & Julian Thumboo. (2019) Prevalence of and factors associated with primary medication non‐adherence in chronic disease: A systematic review and meta‐analysis. International Journal of Clinical Practice 73:6, pages e13350.
Crossref
Valeria Raparelli, Marco Proietti, Giulio Francesco Romiti, Andrea Lenzi & Stefania Basili. (2019) The Sex-Specific Detrimental Effect of Diabetes and Gender-Related Factors on Pre-admission Medication Adherence Among Patients Hospitalized for Ischemic Heart Disease: Insights From EVA Study. Frontiers in Endocrinology 10.
Crossref