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Original Research

Metformin Improves the Depression Symptoms of Women with Polycystic Ovary Syndrome in a Lifestyle Modification Program

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Pages 737-746 | Published online: 15 Apr 2020

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (3)

Mayouri Sukhapure, Kate Eggleston, Anna Fenton, Christopher Frampton, Richard J Porter & Katie M Douglas. (2022) Changes in Mood, Anxiety, and Cognition with Polycystic Ovary Syndrome Treatment: A Longitudinal, Naturalistic Study. Neuropsychiatric Disease and Treatment 18, pages 2703-2712.
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Meiying Sang, Qiong Wu, Yuanyuan Tao, Feifei Huang, Lianlian Lu, Wenting Zhou, Aixiang Li & Shun Bai. (2022) Usage of mobile health interventions among overweight/obese PCOS patients undergoing assisted reproductive technology treatment during the COVID-19 pandemic. Gynecological Endocrinology 38:9, pages 776-780.
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Laís Bhering Martins, Jenneffer Rayane Braga Tibães, Michael Berk & Antonio Lucio Teixeira. (2022) Diabetes and mood disorders: shared mechanisms and therapeutic opportunities. International Journal of Psychiatry in Clinical Practice 26:2, pages 183-195.
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Articles from other publishers (19)

Lindsay R. Standeven, Kelsey Hannan, Bhuchitra Singh & Liisa Hantsoo. (2023) Polycystic Ovary Syndrome. Advances in Psychiatry and Behavioral Health 3:1, pages 91-101.
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Jianhong Liu, Ming Zhang, Dan Deng & Xiao Zhu. (2023) The function, mechanisms, and clinical applications of metformin: potential drug, unlimited potentials. Archives of Pharmacal Research 46:5, pages 389-407.
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Stacey N. Doan, Sunita K. Patel, Bin Xie, Rebecca A. Nelson & Lisa D. Yee. (2023) Disrupting the Mood and Obesity Cycle: The Potential Role of Metformin. Obesities 3:1, pages 59-75.
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Vera Battini, Robbert P. Van Manen, Michele Gringeri, Giulia Mosini, Greta Guarnieri, Anna Bombelli, Marco Pozzi, Maria Nobile, Sonia Radice, Emilio Clementi & Carla Carnovale. (2023) The potential antidepressant effect of antidiabetic agents: New insights from a pharmacovigilance study based on data from the reporting system databases FAERS and VigiBase. Frontiers in Pharmacology 14.
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Temi Toba-Oluboka, Kristýna Vochosková & Tomas Hajek. (2022) Are the antidepressant effects of insulin-sensitizing medications related to improvements in metabolic markers?. Translational Psychiatry 12:1.
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Derya Yuksel Kocak & Meltem Ugurlu. (2022) Depression symptoms and quality of life in women with polycystic ovary syndrome. Perspectives in Psychiatric Care 58:4, pages 2837-2845.
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Chandani Hamal, Lakshmi Sai Deepak Reddy Velugoti, Godfrey Tabowei, Greeshma N Gaddipati, Maria Mukhtar, Mohammed J Alzubaidee, Raga Sruthi Dwarampudi, Sheena Mathew, Sumahitha Bichenapally, Vahe Khachatryan, Asmaa Muazzam & Lubna Mohammed. (2022) Metformin for the Improvement of Comorbid Depression Symptoms in Diabetic Patients: A Systematic Review. Cureus.
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Anuja Dokras. 2022. Polycystic Ovary Syndrome. Polycystic Ovary Syndrome 162 169 .
Hadeer Ehab Barakat, Raghda R. S. Hussein, Ahmed Abdullah Elberry, Mamdouh Ahmed Zaki & Mamdouh Elsherbiny Ramadan. (2022) The impact of metformin use on the outcomes of locally advanced breast cancer patients receiving neoadjuvant chemotherapy: an open-labelled randomized controlled trial. Scientific Reports 12:1.
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Jiqing Yang, Zunyue Zhang, Zhenrong Xie, Ling Bai, Pu Xiong, Fengrong Chen, Tailin Zhu, Qingyan Peng, Hongjin Wu, Yong Zhou, Yuru Ma, Yongjin Zhang, Minghui Chen, Jianyuan Gao, Weiwei Tian, Kai Shi, Yan Du, Yong Duan, Huawei Wang, Yu Xu, Yi-Qun Kuang, Mei Zhu, Juehua Yu & Kunhua Wang. (2022) Metformin modulates microbiota-derived inosine and ameliorates methamphetamine-induced anxiety and depression-like withdrawal symptoms in mice. Biomedicine & Pharmacotherapy 149, pages 112837.
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Thomas D Clark, Amy C Reichelt, Olivia Ghosh-Swaby, Stephen J Simpson & Angela J Crean. (2022) Nutrition, anxiety and hormones. Why sex differences matter in the link between obesity and behavior.. Physiology & Behavior 247, pages 113713.
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Wen-Hsuan Tsai, Fung-Chang Sung, Lu-Ting Chiu, Ying-Hsiu Shih, Ming-Chieh Tsai & Shu-I Wu. (2022) Decreased Risk of Anxiety in Diabetic Patients Receiving Glucagon-like Peptide-1 Receptor Agonist: A Nationwide, Population-Based Cohort Study. Frontiers in Pharmacology 13.
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Snigdha Alur-Gupta & Anuja Dokras. 2022. Polycystic Ovary Syndrome. Polycystic Ovary Syndrome 377 392 .
Yu Song, Huimin Wang, Zhengyan Zhu & Hongli Huang. (2021) Effects of Metformin and Exercise in Polycystic Ovary Syndrome: Systematic Review and Meta-Analysis. Hormone and Metabolic Research 53:11, pages 738-745.
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Ashutosh Tripathi, Giselli Scaini, Tatiana Barichello, João Quevedo & Anilkumar Pillai. (2021) Mitophagy in depression: Pathophysiology and treatment targets. Mitochondrion 61, pages 1-10.
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Stella Papachristou & Nikolaos Papanas. (2021) Reduction of Depression in Diabetes: A New Pleiotropic Action of Metformin?. Diabetes Therapy 12:4, pages 965-968.
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Laili Soleimani, Ramit Ravona-Springer, Hung-Mo Lin, Xiaoyu Liu, Mary Sano, Anthony Heymann & Michal Schnaider Beeri. (2021) Specific Dimensions of Depression Have Different Associations With Cognitive Decline in Older Adults With Type 2 Diabetes. Diabetes Care 44:3, pages 655-662.
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Amira Mohammed Ali & Hiroshi Kunugi. (2020) Intermittent Fasting, Dietary Modifications, and Exercise for the Control of Gestational Diabetes and Maternal Mood Dysregulation: A Review and a Case Report. International Journal of Environmental Research and Public Health 17:24, pages 9379.
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Jiqing Yang, Zunyue Zhang, Zhen-Rong Xie, Ling Bai, Pu Xiong, Fengrong Chen, Tailin Zhu, Qingyan Peng, Hongjin Wu, Yong Zhou, Yuru Ma, Yongjin Zhang, Minghui Chen, Jianyuan Gao, Weiwei Tian, Kai Shi, Yan Du, Yong Duan, Huawei Wang, Yu Xu, Yi-Qun Kuang, Juehua Yu & Kunhua Wang. (2021) Metformin Modulates Microbiota-Derived Inosine and Ameliorates Methamphetamine-Induced Anxiety and Depression-Like Withdrawal Symptoms in Mice. SSRN Electronic Journal.
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