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Original Research

Results of a human factors experiment of the usability and patient acceptance of a new autoinjector in patients with rheumatoid arthritis

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Pages 199-209 | Published online: 11 Feb 2014

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (7)

Andreas Schneider, Philipp Richard, Philippe Mueller, Christoph Jordi, Mary Yovanoff & Jakob Lange. (2021) User-Centric Approach to Specifying Technical Attributes of Drug Delivery Devices: Empirical Study of Autoinjector-Cap Removal Forces. Patient Preference and Adherence 15, pages 159-168.
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Jesús Tornero Molina, Juan Carlos López Robledillo & Núria Casamira Ruiz. (2021) Potential Benefits of the Self-Administration of Subcutaneous Methotrexate with Autoinjector Devices for Patients: A Review. Drug, Healthcare and Patient Safety 13, pages 81-94.
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David Bernstein, Ian D. Pavord, Kenneth R. Chapman, Richard Follows, Jane H. Bentley, Isabelle Pouliquen & Eric Bradford. (2020) Usability of mepolizumab single-use prefilled autoinjector for patient self-administration. Journal of Asthma 57:9, pages 987-998.
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Xiao Xiao, Wei Li, Corbin Clawson, David Karvani, Perceval Sondag & James K Hahn. (2018) Evaluation of performance, acceptance, and compliance of an auto-injector in healthy and rheumatoid arthritic subjects measured by a motion capture system. Patient Preference and Adherence 12, pages 515-526.
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Andreas E. Schneider & Jakob Lange. (2018) Pen devices for self-injection: contrasting measured injection force with users’ perceived ease of injection. Expert Opinion on Drug Delivery 15:2, pages 115-125.
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Kristina Callis Duffin, Michael Bukhalo, Margaret A Bobonich, David Shrom, Fangyi Zhao, James R Kershner, Anne Gill, Beth Pangallo, Catherine L Shuler & Jerry Bagel. (2016) Usability of a novel disposable autoinjector device for ixekizumab: results from a qualitative study and an open-label clinical trial, including patient-reported experience. Medical Devices: Evidence and Research 9, pages 361-369.
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Jakob Lange, Philipp Richard & Nick Bradley. (2015) Usability of a new disposable autoinjector platform device: results of a formative study conducted with a broad user population. Medical Devices: Evidence and Research 8, pages 255-264.
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Articles from other publishers (16)

Ahad Sabet, Daniel S. Dickerson, Eugenia E. Kunina, Anna Lucia Buccarello & Joëlle Monnet. (2022) A Randomised Controlled Trial Comparing the Pharmacokinetics and Tolerability of the Proposed Adalimumab Biosimilar MSB11022 Delivered via Autoinjector and Pre-filled Syringe in Healthy Subjects. Rheumatology and Therapy 9:2, pages 693-704.
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Antonia Davidson, Darin Brimhall, Jonathan Kay, Edward Keystone, Sang Joon Lee, Sung Hyun Kim, Yun Ju Bae, Eun Jin Choi & Daniel E. Furst. (2021) Randomised, phase I pharmacokinetic study of adalimumab biosimilar CT‐P17 (40 mg/0.4 mL) by autoinjector and prefilled syringe in healthy subjects. British Journal of Clinical Pharmacology 87:11, pages 4323-4333.
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Anitha Roy, Royapuram Veeraragavan Geetha, Anitha Magesh, Rajagopalan Vijayaraghavan & Veerasamy Ravichandran. (2021) Autoinjector – A smart device for emergency cum personal therapy. Saudi Pharmaceutical Journal 29:10, pages 1205-1215.
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Irina Cherniakov, Orit Cohen‐Barak, Ryan Tiver, Michael Gillespie, Yoel Kessler, Maria Gutierrez, Michele Rasamoelisolo, Shawn Li, Honglue Shen, Hussein Hallak, Pippa S. Loupe, Michael Smith, Laura Rabinovich‐Guilatt & Ofer Spiegelstein. (2021) A Pharmacokinetic Bioequivalence Study of Fremanezumab Administered Subcutaneously Using an Autoinjector and a Prefilled Syringe. Clinical Pharmacology in Drug Development 10:9, pages 1018-1027.
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Russell J. Branaghan, Joseph S. O’Brian, Emily A. Hildebrand & L. Bryant FosterRussell J. Branaghan, Joseph S. O’Brian, Emily A. Hildebrand & L. Bryant Foster. 2021. Humanizing Healthcare – Human Factors for Medical Device Design. Humanizing Healthcare – Human Factors for Medical Device Design 49 67 .
Steve Fenwick, Kunal Thakur & Duncan Munro. (2019) Nurse and Patient Perceptions and Preferences for Subcutaneous Autoinjectors for Inflammatory Joint or Bowel Disease: Findings from a European Survey. Rheumatology and Therapy 6:2, pages 195-206.
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Helen L. Quinn, Carmel M. Hughes & Ryan F. Donnelly. (2017) In vivo and qualitative studies investigating the translational potential of microneedles for use in the older population. Drug Delivery and Translational Research 8:2, pages 307-316.
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Ebony Dashiell-Aje, Gale Harding, Katie Pascoe, Jane DeVries, Pamela Berry & Sulabha Ramachandran. (2017) Patient Evaluation of Satisfaction and Outcomes with an Autoinjector for Self-Administration of Subcutaneous Belimumab in Patients with Systemic Lupus Erythematosus. The Patient - Patient-Centered Outcomes Research 11:1, pages 119-129.
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Y. Zhuang, D. E. de Vries, S. J. Marciniak, H. Liu, H. Zhou, H. M. Davis, F. Leon, D. Raible & Z. Xu. (2017) Absolute Bioavailability and Pharmacokinetic Comparability of Sirukumab Following Subcutaneous Administration by a Prefilled Syringe or an Autoinjector. Clinical Pharmacology in Drug Development 6:6, pages 570-576.
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K. Callis Duffin, J. Bagel, M. Bukhalo, I.J. Mercado Clement, S.L. Choi, F. Zhao, A. Gill, B. Pangallo, C. Shuler, L. Mallbris & K. Jackson. (2017) Phase 3, open-label, randomized study of the pharmacokinetics, efficacy and safety of ixekizumab following subcutaneous administration using a prefilled syringe or an autoinjector in patients with moderate-to-severe plaque psoriasis (UNCOVER-A). Journal of the European Academy of Dermatology and Venereology 31:1, pages 107-113.
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L. OtvosJr.Jr.. 2017. Comprehensive Medicinal Chemistry III. Comprehensive Medicinal Chemistry III 131 156 .
Kunal Thakur, Anna Biberger, Alexandra Handrich & Mourad Farouk Rezk. (2016) Patient Perceptions and Preferences of Two Etanercept Autoinjectors for Rheumatoid Arthritis: Findings from a Patient Survey in Europe. Rheumatology and Therapy 3:2, pages 245-256.
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Ana Barbir, Mark V. Janelli, Michael Y. Lin & Jack T. Dennerlein. (2016) Effects of Epinephrine Auto-Injector Shape and Size on Human Factors Influencing Drug Delivery. Human Factors: The Journal of the Human Factors and Ergonomics Society 58:7, pages 1020-1030.
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Irina Kaplan, Douglas Ross, Fiona Hilton, Diana Morgenstern & Kevin Wolter. (2016) The role of training in effective simulated self-injection of subcutaneous depot medroxyprogesterone acetate: observations from a usability study. Contraception 94:4, pages 314-320.
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Michael Schiff, Joe Koo, Erik Jin, Eric Schiller, Ashley Day, Rebecca Stevens & Christina Laskar. (2016) Usability and Acceptability of the Abatacept Pre-Filled Autoinjector for the Subcutaneous Treatment of Rheumatoid Arthritis. Advances in Therapy 33:2, pages 199-213.
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Tom Sam. 2016. Developing Drug Products in an Aging Society. Developing Drug Products in an Aging Society 403 446 .