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Review

Combination of brinzolamide and brimonidine for glaucoma and ocular hypertension: critical appraisal and patient focus

Pages 853-864 | Published online: 12 Jun 2014

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (5)

Vital Paulino Costa, Tin Aung & Anastasios G. Konstas. (2019) Evolution of the treatment paradigm for maximum medical therapy in glaucoma. Expert Review of Ophthalmology 14:1, pages 33-42.
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Daniel J. Oh, Judy L. Chen, Thasarat S. Vajaranant & Mark S. Dikopf. (2019) Brimonidine tartrate for the treatment of glaucoma. Expert Opinion on Pharmacotherapy 20:1, pages 115-122.
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Jed Asher Lusthaus & Ivan Goldberg. (2017) Brimonidine and brinzolamide for treating glaucoma and ocular hypertension; a safety evaluation. Expert Opinion on Drug Safety 16:9, pages 1071-1078.
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Articles from other publishers (12)

Yash Sharma, Kanak Chahar, Lopamudra Mishra, Lakshmi Kumari, Aarchi Singla, Preeti Patel, Dilpreet Singh & Balak Das Kurmi. (2023) Recent overviews on the drug delivery aspects and applications of brinzolamide for the management of glaucoma. Health Sciences Review 6, pages 100083.
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Jin A Kim & Heeyoung Lee. (2021) Effectiveness and Safety Verification of Brinzolamide Combination Therapy on Primary Open-angle Glaucoma or Ocular Hypertension: A Systematic Review and Meta-analysis Study. Korean Journal of Clinical Pharmacy 31:3, pages 205-215.
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Uttio Roy ChowdhuryRachel A. KudgusBradley H. HolmanTommy A. RinkoskiCheryl R. HannCindy K. BahlerEric McCloudSusan E. ApptJoel M. ReidPeter I. DosaMichael P. Fautsch. (2021) Pharmacological Profile and Ocular Hypotensive Effects of Cromakalim Prodrug 1, a Novel ATP-Sensitive Potassium Channel Opener, in Normotensive Dogs and Nonhuman Primates. Journal of Ocular Pharmacology and Therapeutics 37:5, pages 251-260.
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P S Rastogi, Kanupriya Jain, Ashish Chander & Munavvar Ansari. (2021) A comparative study of topical fixed dose combination of brimonidine (0.2%) plus brinzolamide (1%) versus brimonidine (0.2%) plus timolol (0.5%) in patients of primary open angle glaucoma. Indian Journal of Clinical and Experimental Ophthalmology 7:1, pages 112-117.
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Sudeepthi Padala, Ramam Sripada, Srivalli Bhaskari Padmavathi Gundabattula, Krishna Jyothi Tadi, Prabhakar Rao Nallamothula, Farzaneh Raveshi & Dasaratha Dhanaraju Magharla. (2020) A comparative study on the efficacy of brinzolamide/timolol versus brinzolamide/brimonidine fixed drug combinations in primary open-angle glaucoma. Future Journal of Pharmaceutical Sciences 6:1.
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Péter Kóthy & Gábor Holló. (2019) Real-life experience of using brinzolamide/brimonidine fixed drop combination in a tertiary glaucoma centre. International Ophthalmology 40:2, pages 377-383.
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Jed Lusthaus & Ivan Goldberg. (2019) Current management of glaucoma. Medical Journal of Australia 210:4, pages 180-187.
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Uttio Roy Chowdhury, Peter I. Dosa & Michael P. Fautsch. (2017) ATP sensitive potassium channel openers: A new class of ocular hypotensive agents. Experimental Eye Research 158, pages 85-93.
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R D Fechtner, J S Myers, D A Hubatsch, D L Budenz & H B DuBiner. (2016) Ocular hypotensive effect of fixed-combination brinzolamide/brimonidine adjunctive to a prostaglandin analog: a randomized clinical trial. Eye 30:10, pages 1343-1350.
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Uttio Roy Chowdhury, Cindy K. Bahler, Bradley H. Holman, Peter I. Dosa & Michael P. Fautsch. (2015) Ocular Hypotensive Effects of the ATP-Sensitive Potassium Channel Opener Cromakalim in Human and Murine Experimental Model Systems. PLOS ONE 10:11, pages e0141783.
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Doreen SchmidlLeopold SchmettererGerhard GarhöferAlina Popa-Cherecheanu. (2015) Pharmacotherapy of Glaucoma. Journal of Ocular Pharmacology and Therapeutics 31:2, pages 63-77.
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Sarah L. Greig & Emma D. Deeks. (2015) Brinzolamide/Brimonidine: A Review of Its Use in Patients with Open-Angle Glaucoma or Ocular Hypertension. Drugs & Aging 32:3, pages 251-260.
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