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The Application of Clinical Genetics Volume 6, 2013 - Issue
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Original Research

Association of PPARγ2 gene variant Pro12Ala polymorphism with hypertension and obesity in the aboriginal Qatari population known for being consanguineous

Abdulbari Bener1 Department of Medical Statistics and Epidemiology, Hamad Medical Corporation, Department of Public Health, Weill Cornell Medical College, Doha, Qatar;2 Department of Evidence for Population Health Unit, School of Epidemiology and Health Sciences, University of Manchester, Manchester, UKCorrespondence[email protected]
,
Sarah Darwish3 Department of Endocrinology, Hamad General Hospital, Hamad Medical Corporation, Doha, Qatar
,
Abdulla OAA Al-Hamaq4 Qatar Diabetic Associations and Qatar Foundation, Doha, Qatar
,
Ramzi M Mohammad5 Department of Oncology, Barbara Ann Karmanos Cancer Institute, Wayne State University, School of Medicine, MI, USA;6 Department of Medicine, Hamad Medical Corporation, Doha, Qatar
&
Mohammad T Yousafzai1 Department of Medical Statistics and Epidemiology, Hamad Medical Corporation, Department of Public Health, Weill Cornell Medical College, Doha, Qatar
Pages 103-111 | Published online: 24 Oct 2013

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Zahra Ghorbani, Mohammad Shakiba, Negin Rezavand, Ziba Rahimi, Asad Vaisi-Raygani, Zohreh Rahimi & Ebrahim Shakiba. (2021) Gene variants and haplotypes of Vitamin D biosynthesis, transport, and function in preeclampsia. Hypertension in Pregnancy 40:1, pages 1-8.
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Hassan R. Dhaini & Zeina Daher. (2019) Genetic polymorphisms of PPAR genes and human cancers: evidence for gene–environment interactions. Journal of Environmental Science and Health, Part C 37:3, pages 146-179.
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Articles from other publishers (12)

Riandini Aisyah, Ahmad Hamim Sadewa, Suryono Yudha Patria & Abdul Wahab. (2022) The PPARGC1A Is the Gene Responsible for Thrifty Metabolism Related Metabolic Diseases: A Scoping Review. Genes 13:10, pages 1894.
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Hassan Okati-Aliabad, Alireza Ansari-Moghaddam, Shiva Kargar & Mahdi Mohammadi. (2022) Prevalence of hypertension and pre-hypertension in the Middle East region: a systematic review & meta-analysis. Journal of Human Hypertension 36:9, pages 794-804.
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Abbas Balouchi, Mojgan Haj Ahmadi Pour Rafsanjani, Kholoud Al-Mutawaa, Mahin Naderifar, Hosein Rafiemanesh, Abbas Ebadi, Tahereh Najafi Ghezeljeh, Azita Shahraki-Mohammadi & Adhra Al-Mawali. (2022) Hypertension and Pre-Hypertension in Middle East and North Africa (MENA): A Meta-Analysis of Prevalence, Awareness, Treatment, and Control. Current Problems in Cardiology 47:7, pages 101069.
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Youssra Dakroury, Stephen L. Atkin, Soha R. Dargham, Amal Robay, Juan Rodriguez-Flores, Ronald G. Crystal & Alexandra E. Butler. (2020) Qatari Genotype May Contribute to Complications in Type 2 Diabetes. Journal of Diabetes Research 2020, pages 1-6.
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Miao Zhang, Jianping Zhang, Lifeng Li, Qiang Wang & Limin Feng. (2019) Association between peroxisome proliferator-activated receptor γ-2 gene Pro12Ala polymorphisms and risk of hypertension: an updated meta-analysis. Bioscience Reports 39:2.
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Ebrima Jallow, Hassan Al Hail, Thang S Han, Sapna Sharma, Dirk Deleu, Musab Ali, Hassan Al Hussein, Hassan O Abuzaid, Khalid Sharif, Fahmi Y Khan & Pankaj Sharma. (2019) Current status of stroke in Qatar: Including data from the BRAINS study. JRSM Cardiovascular Disease 8, pages 204800401986916.
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W. Yang, J. Wang, W. Ye & X. Li. (2017) Quantitative evaluation of PPAR-γ2 Pro12Ala polymorphism with hypertensionQuantitative Auswertung des PPAR-γ2 Pro12Ala Polymorphismus bei Hypertonie. Herz 43:8, pages 719-727.
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Josefina Aguayo-Armendáriz, Maricela Montalvo-Corral, Karla A. González-Martínez, María I. Grijalva-Haro, Martha N. Ballesteros-Vásquez, Graciela Caire-Juvera & Silvia Y. Moya-Camarena. (2018) Central obesity and body fat, but not body mass index, are associated with the Pro12Ala polymorphism in the peroxisome proliferator–activated receptor γ gene in a population with a high consumption of saturated and trans-fatty acids. Nutrition Research 57, pages 28-35.
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Mohd Khairi Zahri, Apidi Emilia, Rohayu Izanwati Mohd Rawi, Wan Rohani Wan Taib, Aliya Irshad Sani & Atif Amin Baig. (2016) Contribution of the Pro12Ala polymorphism of peroxisome proliferator-activated receptor Ɣ2 gene in relation to obesity. Meta Gene 10, pages 39-44.
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Laura Soldati, Abdelhamid Kerkadi, Paul Amuna & Annalisa Terranegra. (2015) State of art and science advances on nutrition and nutrigenetics in nutrition-related non-communicable diseases in Middle East. Journal of Translational Medicine 13:1, pages 40.
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Abdulbari Bener & Mohammad T. Yousafzai. (2014) Effect of Ramadan fasting on diabetes mellitus. Journal of the Egyptian Public Health Association 89:2, pages 47-52.
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W.Y. Liu. (2013) Probing the Single Nucleotide Polymorphism (Snp) of Swine PPAR Delta Gene. Biotechnology(Faisalabad) 12:4, pages 183-188.
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