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Therapeutics and Clinical Risk Management Volume 14, 2018 - Issue

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Original Research

Effect of intrawound vancomycin application in spinal surgery on the incidence of surgical site infection: a meta-analysis

Abuduwufuer Tailaiti1 Department of Orthopedic Surgery, Urumqi Friendship Hospital, Xinjiang 86830049, China

Jun Shang2 Department of Orthopedics, People’s Hospital of Linfen, Shanxi, 86041000, China

Shuo Shan3 Department of Spine Surgery, Traditional Chinese Hospital Affiliated With Xinjiang Medical University, Xinjiang 86830000, China

Aikeremujiang Muheremu4 Department of Spine Surgery, Sixth Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang 86830001, China, [email protected]Correspondence[email protected]

Pages 2149-2159 | Published online: 31 Oct 2018

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Ahmed M. Sonbol, Ayman M. Baabdullah, Mohamed Awad A. Mohamed & Farid N. Kassab. (2023) Intrawound low-dose vancomycin is superior to high-dose in controlling the risk of wound dehiscence in spine surgeries. Medicine 102:15, pages e33369.
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Wesam Abuzaiter, Caralee A. Bolton, Anastasia Drakos, Paul Drakos, Alam Hallan, David Warchuk, Karen G.H. Woolfrey & Michael R. Woolfrey. (2023) Is Topical Vancomycin an Option? A Randomized Controlled Trial to Determine the Safety of the Topical Use of Vancomycin Powder in Preventing Postoperative Infections in Total Knee Arthroplasty, as Compared With Standard Postoperative Antibiotics. The Journal of Arthroplasty.
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Ahmed Alawamry, Mansour AbdelMageed Makia & Mohamed Ahmed Samir. (2022) Role of intra-discal Vancomycin instillation in prevention post-operative discitis. Egyptian Journal of Neurosurgery 37:1.
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Jessica A. Nelson, Devin A. Maez, Jordan Kump, Mindy A. Trombley, Michael M. Decker & Dustin L. Richter. (2022) Local Application of Vancomycin in Orthopaedic Surgery—A Review. JBJS Journal of Orthopaedics for Physician Assistants 10:1.
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Lukas Šalaševičius, Nijolė Savičienė, Rasa Alsytė, Diana Gasiūnaitė, Giedrius Bernotavičius, Ona Lapteva, Kęstutis Saniukas, Arūnas Vaitkevičius, Robertas Kvaščevičius, Vidūnas Daugelavičius, Jūratė Šipylaitė & Saulius Ročka. (2021) Protocol of Spinal Deformity Surgery and Anaesthesia in Children and Adult: Recommended Preoperative and Perioperative Diagnostic and Treatment Algorithm in Spinal Deformity Surgery. Lietuvos chirurgija 20:3-4, pages 151-165.
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Zhi Peng, Xiaoying Lin, Xiaolin Kuang, Zhaowei Teng & Sheng Lu. (2021) The application of topical vancomycin powder for the prevention of surgical site infections in primary total hip and knee arthroplasty: A meta-analysis. Orthopaedics & Traumatology: Surgery & Research 107:4, pages 102741.
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Hiroki Ushirozako, Tomohiko Hasegawa, Yu YamatoGo Yoshida, Tatsuya Yasuda, Tomohiro Banno, Hideyuki Arima, Shin OeYuki Mihara, Tomohiro Yamada, Koichiro Ide, Yuh Watanabe, Keichi Nakai, Takaaki Imada & Yukihiro Matsuyama. (2021) Impact of intrawound vancomycin powder on prevention of surgical site infection after posterior spinal surgery. Journal of Neurosurgery: Spine 34:4, pages 656-664.
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Kelly Moore, Rebecca Wilson-van Os, Devendra H. Dusane, Jacob R. Brooks, Craig Delury, Sean S. Aiken, Phillip A. Laycock, Anne C. Sullivan, Jeffrey F. Granger, Matthew V. Dipane, Edward J. McPherson & Paul Stoodley. (2021) Elution Kinetics from Antibiotic-Loaded Calcium Sulfate Beads, Antibiotic-Loaded Polymethacrylate Spacers, and a Powdered Antibiotic Bolus for Surgical Site Infections in a Novel In Vitro Draining Knee Model. Antibiotics 10:3, pages 270.
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Nathan Ringeval, François Decrucq, Pierre Weyrich, Jean François Desrousseaux, Denis Cordonnier, Sahara Graf & Alexis Perrin. (2020) Diagnostic performance of suction drainage fluid culture for acute surgical site infection after aseptic instrumented spine surgery: a retrospective analysis of 363 cases. European Journal of Orthopaedic Surgery & Traumatology 31:1, pages 155-160.
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Hong Xu, Jingli Yang, Jinwei Xie, Zeyu Huang, Qiang Huang, Guorui Cao & Fuxing Pei. (2020) Efficacy and safety of intrawound vancomycin in primary hip and knee arthroplasty. Bone & Joint Research 9:11, pages 778-788.
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Michelle S. Balaratnam, Ann Donnelly, Honey Padilla, Sara Simeoni, Sardar Bahadur, Liz Keenan, Heesook Lee, Rachel Farrell, Carmel Curtis, Robert M. Brownstone, Mary Murphy, Joan Grieve, Colin Shieff, Meenakshi Nayar, Robert D.S. Pitceathly, Gerry Christofi & Valerie L. Stevenson. (2020) Reducing Intrathecal Baclofen Related Infections: Service Evaluation and Best Practice Guidelines. Neuromodulation: Technology at the Neural Interface 23:7, pages 991-995.
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Pedro David Delgado-López, Javier Martín-Alonso, Vicente Martín-Velasco, José Manuel Castilla-Díez, Ana Galacho-Harriero, Sara Ortega-Cubero, Ana Isabel Herrero-Gutiérrez & Antonio Rodríguez-Salazar. (2020) Polvo de vancomicina tópico para la prevención de infección de herida quirúrgica en cirugía electiva de columna por vía posterior. Neurocirugía 31:2, pages 64-75.
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Pedro David Delgado-López, Javier Martín-Alonso, Vicente Martín-Velasco, José Manuel Castilla-Díez, Ana Galacho-Harriero, Sara Ortega-Cubero, Ana Isabel Herrero-Gutiérrez & Antonio Rodríguez-Salazar. (2020) Vancomycin powder for the prevention of surgical site infection in posterior elective spinal surgery. Neurocirugía (English Edition) 31:2, pages 64-75.
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I.A. STEPANOV, V.A. BELOBORODOV, V.E. BORISOV, M.A. ALIEV, V.V. SHEPELEV & Yu.Ya. PESTRYAKOV. (2020) The effectiveness of local application of vancomycin powder in the prevention of surgical site infections in spine surgery: a meta-analysis. Khirurgiya. Zhurnal im. N.I. Pirogova:6, pages 60.
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Aron Keshishian, Andrew Foster, Georg Matziolis, T. Fintan Moriarty & Henk Eijer. 2020. Racing for the Surface. Racing for the Surface 57 74 .

Thomas K. Fehring, Keith A. Fehring, Angela Hewlett, Carlos A. Higuera, Jesse E. Otero & Aaron Tande. (2019) What’s New in Musculoskeletal Infection. Journal of Bone and Joint Surgery 101:14, pages 1237-1244.
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M. Krause, C. V. Mahr, S. Schob, U. Nestler & R. Wachowiak. (2019) Topical instillation of vancomycin lowers the rate of CSF shunt infections in children. Child's Nervous System 35:7, pages 1155-1157.
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Tanner N. Womble, John D. King, Dustin H. Hamilton, Max A. Shrout, Cale A. Jacobs & Stephen T. Duncan. (2019) Greater Rates of Acute Kidney Injury in African American Total Knee Arthroplasty Patients. The Journal of Arthroplasty 34:6, pages 1240-1243.
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Geeta Singh, Deepak Passi, Deepti Daga, Abhigyan Manas, U Vignesh & SujayMilind Bhave. (2019) Study of antibiotic efficacy of topical vancomycin powder in treatment of infected mandibular fractures and soft tissue surgical site infections. Journal of Family Medicine and Primary Care 8:10, pages 3340.
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Effect of intrawound vancomycin application in spinal surgery on the incidence of surgical site infection: a meta-analysis

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Effect of intrawound vancomycin application in spinal surgery on the incidence of surgical site infection: a meta-analysis

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