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Review

Long-term treatment of osteoporosis: safety and efficacy appraisal of denosumab

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Pages 295-306 | Published online: 19 Jun 2012

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (8)

Maria P. Yavropoulou, Polyzois Makras & Athanasios D. Anastasilakis. (2019) Bazedoxifene for the treatment of osteoporosis. Expert Opinion on Pharmacotherapy 20:10, pages 1201-1210.
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Koji Ishikawa, Takashi Nagai, Keizo Sakamoto, Kenji Ohara, Takeshi Eguro, Hiroshi Ito, Yoichi Toyoshima, Akatsuki Kokaze, Tomoaki Toyone & Katsunori Inagaki. (2016) High bone turnover elevates the risk of denosumab-induced hypocalcemia in women with postmenopausal osteoporosis. Therapeutics and Clinical Risk Management 12, pages 1831-1840.
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Tanya A Enderli, Stephanie R Burtch, Jara N Templet & Alessandra Carriero. (2016) Animal models of osteogenesis imperfecta: applications in clinical research. Orthopedic Research and Reviews 8, pages 41-55.
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Josep Darbà, Lisette Kaskens, Francesc Sorio Vilela & Mickael Lothgren. (2015) Cost-utility of denosumab for the treatment of postmenopausal osteoporosis in Spain. ClinicoEconomics and Outcomes Research 7, pages 105-117.
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Barry S Komm, Diana Morgenstern, Luis A Yamamoto & Simon N Jenkins. (2015) The safety and tolerability profile of therapies for the prevention and treatment of osteoporosis in postmenopausal women. Expert Review of Clinical Pharmacology 8:6, pages 769-784.
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Colby A Souders, Stuart C Nelson, Yang Wang, Andrew R Crowley, Mark S Klempner & William Thomas$suffix/text()$suffix/text(). (2015) A novel in vitro assay to predict neonatal Fc receptor-mediated human IgG half-life. mAbs 7:5, pages 912-921.
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Leos Fuksa & Magda Vytrisalova. (2015) Adherence to denosumab in the treatment of osteoporosis and its utilization in the Czech Republic. Current Medical Research and Opinion 31:9, pages 1645-1653.
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Garry M Walsh. (2012) Treatment options for postmenopausal osteoporosis. Therapeutics and Clinical Risk Management 8, pages 367-368.
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Anthony Colella, Elaine Yu, Paul Sambrook, Toby Hughes & Alastair Goss. (2023) What is the Risk of Developing Osteonecrosis Following Dental Extractions for Patients on Denosumab for Osteoporosis?. Journal of Oral and Maxillofacial Surgery 81:2, pages 232-237.
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Riyad N. H. Seervai, Sarah K. Friske, Emily Y. Chu, Rhea Phillips, Kelly C. Nelson, Auris Huen, Woo Cheal Cho, Phyu P. Aung, Carlos A. Torres‐Cabala, Victor G. Prieto & Jonathan L. Curry. (2022) The diverse landscape of dermatologic toxicities of non‐immune checkpoint inhibitor monoclonal antibody‐based cancer therapy. Journal of Cutaneous Pathology 50:1, pages 72-95.
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T. Hasegawa, N. Ueda, SI. Yamada, S. Kato, E. Iwata, S. Hayashida, Y. Kojima, M. Shinohara, I. Tojo, H. Nakahara, T. Yamaguchi, T. Kirita, H. Kurita, Y. Shibuya, S. Soutome & M. Akashi. (2021) Denosumab-related osteonecrosis of the jaw after tooth extraction and the effects of a short drug holiday in cancer patients: a multicenter retrospective study. Osteoporosis International 32:11, pages 2323-2333.
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Long Zhou, Hanyi Song, Yiqi Zhang, Zhaozhou Ren, Minghe Li & Qin Fu. (2020) Polyphyllin VII attenuated RANKL-induced osteoclast differentiation via inhibiting of TRAF6/c-Src/PI3K pathway and ROS production. BMC Musculoskeletal Disorders 21:1.
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Zi Zou, Wei Liu, Lihua Cao, Ying Liu, Tiantian He, Shuping Peng & Cijun Shuai. (2020) Advances in the occurrence and biotherapy of osteoporosis. Biochemical Society Transactions 48:4, pages 1623-1636.
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Linda Sequeira, John Nguyen, Liyun Wang & Anja Nohe. (2020) A Novel Peptide, CK2.3, Improved Bone Formation in Ovariectomized Sprague Dawley Rats. International Journal of Molecular Sciences 21:14, pages 4874.
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Ning Zhang, Zong-Kang Zhang, Yuanyuan Yu, Zhenjian Zhuo, Ge Zhang & Bao-Ting Zhang. (2020) Pros and Cons of Denosumab Treatment for Osteoporosis and Implication for RANKL Aptamer Therapy. Frontiers in Cell and Developmental Biology 8.
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Satoe Okuma, Yuhei Matsuda, Yoshiki Nariai, Masaaki Karino, Ritsuro Suzuki & Takahiro Kanno. (2020) A Retrospective Observational Study of Risk Factors for Denosumab-Related Osteonecrosis of the Jaw in Patients with Bone Metastases from Solid Cancers. Cancers 12:5, pages 1209.
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Soo Min Jang, Smitha Anam, Tara Pringle, Paul Lahren & Sergio Infante. (2020) Contrasting PTH Response of Denosumab Use in Dialysis Patients: A Report of 2 Cases. Pharmacy 8:2, pages 59.
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