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Review

New advances in the treatment of gout: review of pegloticase

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Pages 543-550 | Published online: 27 Oct 2010

Keep up to date with the latest research on this topic with citation updates for this article.

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Yingchun Zeng, Yu Ma, Zhengyu Yang, Jiamin Mao & Yaxin Zheng. (2020) Antihyperuricemic efficacy of Scopoletin-loaded Soluplus micelles in yeast extract/potassium oxonate-induced hyperuricemic mice. Drug Development and Industrial Pharmacy 46:9, pages 1550-1557.
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T. Bardin & G. Desideri. (2013) How to manage patients with gout. Current Medical Research and Opinion 29:sup3, pages 17-24.
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Amish J Dave, Victoria M Kelly & Eswar Krishnan. (2012) Pegloticase and the patient with treatment-failure gout. Expert Review of Clinical Pharmacology 5:5, pages 501-508.
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Anne M. Talkington, Morgan D. McSweeney, Tao Zhang, Zibo Li, Andrew C. Nyborg, Brian LaMoreaux, Eric W. Livingston, Jonathan E. Frank, Hong Yuan & Samuel K. Lai. (2021) High MW polyethylene glycol prolongs circulation of pegloticase in mice with anti-PEG antibodies. Journal of Controlled Release 338, pages 804-812.
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Pallavi Kiran, Amreen Khan, Suditi Neekhra, Shubham Pallod & Rohit Srivastava. (2021) Nanohybrids as Protein-Polymer Conjugate Multimodal Therapeutics. Frontiers in Medical Technology 3.
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Puja P. Khanna, Dinesh Khanna, Gary Cutter, Jeff Foster, Joshua Melnick, Sara Jaafar, Stephanie Biggers, A. K. M. Fazlur Rahman, Hui‐Chien Kuo, Michelle Feese, Alan Kivitz, Charles King, William Shergy, Jeff Kent, Paul M. Peloso, Maria I. Danila & Kenneth G. Saag. (2021) Reducing Immunogenicity of Pegloticase With Concomitant Use of Mycophenolate Mofetil in Patients With Refractory Gout: A Phase II, Randomized, Double‐Blind, Placebo‐Controlled Trial. Arthritis & Rheumatology 73:8, pages 1523-1532.
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Victoria M. Hall, Alyssa Thornton, Elizabeth K. Miehls, Jeffery A. Bertke & Jennifer A. Swift. (2019) Uric Acid Crystallization Interrupted with Competing Binding Agents. Crystal Growth & Design 19:12, pages 7363-7371.
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Feng Sun, Zhendong Wang, Zhifang Yang, Yan Li, Huifei Cui, Chunhui Liu, Dezong Gao, Fengshan Wang & Haining Tan. (2019) Characterization, bioactivity and pharmacokinetic study of a novel carbohydrate-peptide polymer: Glycol-split heparin-endostatin2 (GSHP-ES2). Carbohydrate Polymers 207, pages 79-90.
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Rong-Jane Chen, Mei-Huei Chen, Yen-Lin Chen, Ching-Mao Hsiao, Hsiu-Min Chen, Siao-Jhen Chen, Ming-Der Wu, Yi-Jen Yech, Gwo-Fang Yuan & Ying-Jan Wang. (2017) Evaluating the urate-lowering effects of different microbial fermented extracts in hyperuricemic models accompanied with a safety study. Journal of Food and Drug Analysis 25:3, pages 597-606.
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Luca Ronda, Marialaura Marchetti, Riccardo Piano, Anastasia Liuzzi, Romina Corsini, Riccardo Percudani & Stefano Bettati. (2017) A Trivalent Enzymatic System for Uricolytic Therapy of HPRT Deficiency and Lesch-Nyhan Disease. Pharmaceutical Research 34:7, pages 1477-1490.
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Yu Mima, Amr S. Abu Lila, Taro Shimizu, Masami Ukawa, Hidenori Ando, Yasuko Kurata & Tatsuhiro Ishida. (2017) Ganglioside inserted into PEGylated liposome attenuates anti-PEG immunity. Journal of Controlled Release 250, pages 20-26.
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Jinjie Zhang, Xiao Shuai, Jianbo Li, Nanxi Xiang, Tao Gong & Zhirong Zhang. (2016) Biodistribution, hypouricemic efficacy and therapeutic mechanism of morin phospholipid complex loaded self-nanoemulsifying drug delivery systems in an experimental hyperuricemic model in rats. Journal of Pharmacy and Pharmacology 68:1, pages 14-25.
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Yuhui Gong, Jean-Christophe Leroux & Marc A. Gauthier. (2015) Releasable Conjugation of Polymers to Proteins. Bioconjugate Chemistry 26:7, pages 1172-1181.
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Davide Grassi, Roberto Pontremoli, Raffaella Bocale, Claudio Ferri & Giovambattista Desideri. (2014) Therapeutic Approaches to Chronic Hyperuricemia and Gout. High Blood Pressure & Cardiovascular Prevention 21:4, pages 243-250.
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Everett Stone, Olga Paley, Jian Hu, Barbara Ekerdt, Nai-Kong Cheung & George Georgiou. (2012) De Novo Engineering of a Human Cystathionine-γ-Lyase for Systemic l -Methionine Depletion Cancer Therapy . ACS Chemical Biology 7:11, pages 1822-1829.
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Rodolfo V. Curiel & Nicolas J. Guzman. (2012) Challenges Associated with the Management of Gouty Arthritis in Patients with Chronic Kidney Disease: A Systematic Review. Seminars in Arthritis and Rheumatism 42:2, pages 166-178.
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E. Suresh & P. Das. (2011) Recent advances in management of gout. QJM 105:5, pages 407-417.
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Ricardo P. Garay, M. Raafat El-Gewely, Jean-Pierre Labaune & Pascal Richette. (2012) Therapeutic perspectives on uricases for gout. Joint Bone Spine 79:3, pages 237-242.
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Chandrika B-Rao, Asha Kulkarni-Almeida, Kamlesh V. Katkar, Smriti Khanna, Usha Ghosh, Ashish Keche, Pranay Shah, Ankita Srivastava, Vaidehi Korde, Kumar V.S. Nemmani, Nitin J. Deshmukh, Amol Dixit, Manoja K. Brahma, Umakant Bahirat, Lalit Doshi, Rajiv Sharma & H. Sivaramakrishnan. (2012) Identification of novel isocytosine derivatives as xanthine oxidase inhibitors from a set of virtual screening hits. Bioorganic & Medicinal Chemistry 20:9, pages 2930-2939.
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Herbert SB Baraf & Alan K Matsumoto. (2012) Pegloticase: a new biologic for treating advanced gout. International Journal of Clinical Rheumatology 7:2, pages 143-154.
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Jennifer A Shannon & Sabrina W Cole. (2012) Pegloticase: A Novel Agent for Treatment-Refractory Gout. Annals of Pharmacotherapy 46:3, pages 368-376.
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Shang-Tse Ho, Yu-Tang Tung, Chi-Chang Huang, Chao-Lin Kuo, Chi-Chen Lin, Suh-Ching Yang & Jyh-Horng Wu. (2012) The Hypouricemic Effect of Balanophora laxiflora Extracts and Derived Phytochemicals in Hyperuricemic Mice . Evidence-Based Complementary and Alternative Medicine 2012, pages 1-7.
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Simone Fargetti, Claudia Goldenstein-Schainberg, Andressa Silva Abreu & Ricardo Fuller. (2012) Refractory Gout Attack. Case Reports in Medicine 2012, pages 1-4.
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Ricardo P. Garay, Raafat El-Gewely, Jean-Pierre Labaune & Pascal Richette. (2012) Perspectives des uricases dans la goutte. Revue du Rhumatisme 79:1, pages 17-22.
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Frédéric Lioté & Robert Terkeltaub. 2012. Gout & Other Crystal Arthropathies. Gout & Other Crystal Arthropathies 194 208 .
George Nuki. 2012. Gout & Other Crystal Arthropathies. Gout & Other Crystal Arthropathies 174 186 .
M P Keith & W R Gilliland. (2011) Improving the Use of Allopurinol in Chronic Gout: Monitoring Oxypurinol Levels to Guide Therapy. Clinical Pharmacology & Therapeutics 90:3, pages 363-364.
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Muhammad K. NISAR & K. BABURAJ. (2011) A challenging case of gout and failure of anti-TNF therapy- Are current treatments adequate?. International Journal of Rheumatic Diseases 14:3, pages e42-e43.
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