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Therapeutics and Clinical Risk Management Volume 11, 2015 - Issue
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Review

Pharmacologic rationale underlying the therapeutic effects of tiotropium/olodaterol in COPD

Girolamo Pelaia1 Department of Medical and Surgical Sciences, Magna Græcia University of Catanzaro, Catanzaro, ItalyCorrespondence[email protected]
,
Alessandro Vatrella2 Department of Medicine and Surgery, University of Salerno, Salerno, Italy
,
Maria Teresa Busceti1 Department of Medical and Surgical Sciences, Magna Græcia University of Catanzaro, Catanzaro, Italy
,
Luca Gallelli3 Department of Health Science, Magna Græcia University of Catanzaro, Catanzaro, Italy
,
Cecilia Calabrese4 Department of Cardio-Thoracic and Respiratory Sciences, Second University of Naples, Naples, Italy
,
Rosa Terracciano3 Department of Health Science, Magna Græcia University of Catanzaro, Catanzaro, Italy
,
Nicola Lombardo1 Department of Medical and Surgical Sciences, Magna Græcia University of Catanzaro, Catanzaro, Italy
&
Rosario Maselli1 Department of Medical and Surgical Sciences, Magna Græcia University of Catanzaro, Catanzaro, Italy
 show all
Pages 1563-1572 | Published online: 08 Oct 2015

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Corrado Pelaia, Anna Ferrante Bannera, Fioramante Lello Rotundo, Francesco Giuseppe Tropea, Giuseppe Armentaro, Angelantonio Maglio, Angela Sciacqua, Alessandro Vatrella & Girolamo Pelaia. (2023) Clinical and Functional Effects of Inhaled Dual Therapy Umeclidinium/Vilanterol in Patients with Chronic Obstructive Pulmonary Disease: A Real-Life Study. International Journal of Chronic Obstructive Pulmonary Disease 18, pages 995-1002.
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Alessandro Vatrella, Angelantonio Maglio, Corrado Pelaia, Girolamo Pelaia & Carolina Vitale. (2020) Pharmacotherapeutic strategies for critical asthma syndrome: a look at the state of the art. Expert Opinion on Pharmacotherapy 21:12, pages 1505-1515.
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Cecilia Calabrese, Adriano Costigliola, Marianna Maffei, Vittorio Simeon, Francesco Perna, Eugenio Tremante, Elena Merola, Carlo Antonio Leone & Andrea Bianco. (2018) Clinical impact of nasal budesonide treatment on COPD patients with coexistent rhinitis. International Journal of Chronic Obstructive Pulmonary Disease 13, pages 2025-2032.
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Nicola A Hanania, Suzanne C. Lareau & Barbara P. Yawn. (2017) Safety of inhaled long-acting anti-muscarinic agents in COPD. Postgraduate Medicine 129:5, pages 500-512.
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Articles from other publishers (11)

Tai Joon An, Ji Hye Kim, Jung Hur, Chan Kwon Park, Jeong Uk Lim, Seohyun Kim, Chin Kook Rhee & Hyoung Kyu Yoon. (2023) Tiotropium Bromide Improves Neutrophilic Asthma by Recovering Histone Deacetylase 2 Activity. Journal of Korean Medical Science 38:12.
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Haoqi Zheng, Xiuhua Yu, Yuquan Chen, Wenying Lin & Li Liu. (2022) Effects of Inhaled Corticosteroids on Lung Function in Children With Post-infectious Bronchiolitis Obliterans in Remission. Frontiers in Pediatrics 10.
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Gao Zhen, Liu Yingying & Dong Jingcheng. (2022) Drug Therapies for COPD: A Bibliometric Review From 1980 to 2021. Frontiers in Pharmacology 13.
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Corrado Pelaia, Giada Procopio, Maria Rosaria Deodato, Olivia Florio, Angelantonio Maglio, Angela Sciacqua, Alessandro Vatrella & Girolamo Pelaia. (2021) Real-Life Clinical and Functional Effects of Fluticasone Furoate/Umeclidinium/Vilanterol-Combined Triple Therapy in Patients with Chronic Obstructive Pulmonary Disease. Respiration 100:2, pages 127-134.
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Anneke Himstedt, Per Bäckman & Jens Markus Borghardt. 2021. Inhaled Medicines. Inhaled Medicines 319 358 .
Giusy Daniela Albano, Anna Bonanno, Monica Moscato, Giulia Anzalone, Caterina Di Sano, Loredana Riccobono, Sally E. Wenzel & Mirella Profita. (2018) Crosstalk between mAChRM3 and β2AR, via acetylcholine PI3/PKC/PBEP1/Raf-1 MEK1/2/ERK1/2 pathway activation, in human bronchial epithelial cells after long-term cigarette smoke exposure. Life Sciences 192, pages 99-109.
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Gerrit John-Schuster, Stan de Kleijn, Yolanda van Wijck, Veerle Kremer, Hermelijn H. Smits, Michael P. Pieper, Pieter S. Hiemstra & Christian Taube. (2017) The effect of tiotropium in combination with olodaterol on house dust mite-induced allergic airway disease. Pulmonary Pharmacology & Therapeutics 45, pages 210-217.
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David M. Halpin, Alan G. Kaplan & Richard K. Russell. (2017) Why choose tiotropium for my patient? A comprehensive review of actions and outcomes versus other bronchodilators. Respiratory Medicine 128, pages 28-41.
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Michael J. Berridge. (2016) The Inositol Trisphosphate/Calcium Signaling Pathway in Health and Disease. Physiological Reviews 96:4, pages 1261-1296.
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Cecilia Calabrese, Nadia Corcione, Gaetano Rea, Francesco Stefanelli, Ilernando Meoli & Alessandro Vatrella. (2016) Impact of long-term treatment with inhaled corticosteroids and bronchodilators on lung function in a patient with post-infectious bronchiolitis obliterans. Jornal Brasileiro de Pneumologia 42:3, pages 228-231.
Crossref
David M.G. Halpin, Claus Vogelmeier, Michael P. Pieper, Norbert Metzdorf, Frank Richard & Antonio Anzueto. (2016) Effect of tiotropium on COPD exacerbations: A systematic review. Respiratory Medicine 114, pages 1-8.
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