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Vascular Health and Risk Management Volume 17, 2021 - Issue
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Review

Epigenetic Therapies for Heart Failure: Current Insights and Future Potential

Claudio Napoli1 Department of Advanced Medical and Surgical Sciences (DAMSS), University of Campania “Luigi Vanvitelli”, Naples, 80138, ItalyView further author information
,
Paola Bontempo2 Department of Precision Medicine, University of Campania “Luigi Vanvitelli”, Naples, 80138, ItalyView further author information
,
Vittorio Palmieri3 Department of Cardiac Surgery and Transplantation, Heart Transplantation Unit in Adults of the ‘Ospedali dei Colli Monaldi-Cotugno-CTO’, Naples, ItalyView further author information
,
Enrico Coscioni4 Department of Cardiac Surgery, Azienda Ospedaliera Universitaria San Giovanni di Dio e Ruggi d’Aragona, Salerno, ItalyORCID Iconhttps://orcid.org/0000-0002-4373-3760View further author information
ORCID Icon,
Ciro Maiello5 Department of Cardiovascular Surgery and Transplants, Monaldi Hospital, Azienda dei Colli, Naples, ItalyView further author information
,
Francesco Donatelli6 Chair of Cardiac Surgery, Department of Cardiothoracic Center, Istituto Clinico Sant’Ambrogio, University of Milan, Milan, ItalyORCID Iconhttps://orcid.org/0000-0003-2839-0373View further author information
ORCID Icon &
Giuditta Benincasa1 Department of Advanced Medical and Surgical Sciences (DAMSS), University of Campania “Luigi Vanvitelli”, Naples, 80138, ItalyCorrespondence[email protected]
View further author information
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Pages 247-254 | Published online: 24 May 2021

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Qiang Yang, Jing Gao, Tian-Yu Wang, Jun-Can Ding & Peng-Fei Hu. (2023) Integration of RNA-Seq and Machine Learning Identifies Hub Genes for Empagliflozin Benefitable Heart Failure with Reduced Ejection Fraction. Journal of Inflammation Research 16, pages 4733-4749.
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Articles from other publishers (18)

Giuditta Benincasa, Claudio Napoli, Joseph Loscalzo & Bradley A. Maron. (2023) Pursuing functional biomarkers in complex disease: Focus on pulmonary arterial hypertension. American Heart Journal 258, pages 96-113.
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Boce Song, Beili Xie, Mingwang Liu, Haohao Li, Dazhuo Shi & Fuhai Zhao. (2023) Bibliometric and visual analysis of RAN methylation in cardiovascular disease. Frontiers in Cardiovascular Medicine 10.
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Masafumi Funamoto, Masaki Imanishi, Koichiro Tsuchiya & Yasumasa Ikeda. (2023) Roles of histone acetylation sites in cardiac hypertrophy and heart failure. Frontiers in Cardiovascular Medicine 10.
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Timothy A McKinsey, Roger Foo, Chukwuemeka George Anene-Nzelu, Joshua G Travers, Ronald J Vagnozzi, Natalie Weber & Thomas Thum. (2022) Emerging epigenetic therapies of cardiac fibrosis and remodelling in heart failure: from basic mechanisms to early clinical development. Cardiovascular Research 118:18, pages 3482-3498.
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Giuditta Benincasa, Mario Viglietti, Enrico Coscioni & Claudio Napoli. (2023) “Transplantomics” for predicting allograft rejection: real-life applications and new strategies from Network Medicine. Human Immunology 84:2, pages 89-97.
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Donato Gemmati & Veronica Tisato. 2023. Principles of Gender-Specific Medicine. Principles of Gender-Specific Medicine 393 408 .
Lindsay Kraus. (2022) Targeting Epigenetic Regulation of Cardiomyocytes through Development for Therapeutic Cardiac Regeneration after Heart Failure. International Journal of Molecular Sciences 23:19, pages 11878.
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Claudio Napoli, Giuditta Benincasa & Samer Ellahham. (2022) Precision Medicine in Patients with Differential Diabetic Phenotypes: Novel Opportunities from Network Medicine. Current Diabetes Reviews 18:8.
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Naranjan S. Dhalla, Sukhwinder K. Bhullar & Anureet K. Shah. (2022) Future scope and challenges for congestive heart failure: moving toward development of pharmacotherapy. Canadian Journal of Physiology and Pharmacology 100:9, pages 834-847.
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Kun Zhao, Yukang Mao, Yansong Li, Chuanxi Yang, Kai Wang & Jing Zhang. (2022) The roles and mechanisms of epigenetic regulation in pathological myocardial remodeling. Frontiers in Cardiovascular Medicine 9.
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Samuele Ambrosini, Era Gorica, Shafeeq A. Mohammed, Sarah Costantino, Frank Ruschitzka & Francesco Paneni. (2022) Epigenetic remodeling in heart failure with preserved ejection fraction. Current Opinion in Cardiology 37:3, pages 219-226.
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Estefanía Tarazón, Lorena Pérez-Carrillo, Isaac Giménez-Escamilla, María García-Manzanares, Luis Martínez-Dolz, Manuel Portolés & Esther Roselló-Lletí. (2022) DNMT3B System Dysregulation Contributes to the Hypomethylated State in Ischaemic Human Hearts. Biomedicines 10:4, pages 866.
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Alexander E. Berezin, Ioana Mozos & Daniel Petrovič. (2022) Editorial: Epigenetics in Heart Failure Developing: The Orchestra of Etiology and Comorbidities. Frontiers in Cardiovascular Medicine 9.
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Nan Zhang, Yueying Wang, Gary Tse, Panagiotis Korantzopoulos, Konstantinos P Letsas, Qingpeng Zhang, Guangping Li, Gregory Y H Lip & Tong Liu. (2021) Effect of sodium-glucose cotransporter-2 inhibitors on cardiac remodelling: a systematic review and meta-analysis. European Journal of Preventive Cardiology 28:17, pages 1961-1973.
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Edoardo GrondaGary D. LopaschukArduino ArduiniAntonio SantoroGiuditta BenincasaAlberto PalazzuoliDomenico GabrielliClaudio Napoli. (2022) Mechanisms of action of SGLT2 inhibitors and their beneficial effects on the cardiorenal axis. Canadian Journal of Physiology and Pharmacology 100:2, pages 93-106.
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Rosaria Benedetti, Giuditta Benincasa, Kimberly Glass, Ugo Chianese, Maria Teresa Vietri, Raffaella Congi, Lucia Altucci & Claudio Napoli. (2022) Effects of novel SGLT2 inhibitors on cancer incidence in hyperglycemic patients: a meta-analysis of randomized clinical trials. Pharmacological Research 175, pages 106039.
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Richard A. Stein & Abhi N. Deverakonda. 2023. Cancer Research: An Interdisciplinary Approach. Cancer Research: An Interdisciplinary Approach 183 240 .
Concetta Schiano, Monica Franzese, Filippo Geraci, Mario Zanfardino, Ciro Maiello, Vittorio Palmieri, Andrea Soricelli, Vincenzo Grimaldi, Enrico Coscioni, Marco Salvatore & Claudio Napoli. (2021) Machine Learning and Bioinformatics Framework Integration to Potential Familial DCM-Related Markers Discovery. Genes 12:12, pages 1946.
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