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Review

Direct oral anticoagulants in the treatment of venous thromboembolism, with a focus on patients with pulmonary embolism: an evidence-based review

Antonio Gómez-Outes1 Division of Pharmacology and Clinical Evaluation, Medicines for Human Use, Spanish Agency for Medicines and Medical Devices (AEMPS), Madrid, SpainCorrespondence[email protected]

Mª Luisa Suárez-Gea1 Division of Pharmacology and Clinical Evaluation, Medicines for Human Use, Spanish Agency for Medicines and Medical Devices (AEMPS), Madrid, Spain

Ramón Lecumberri2 Department of Hematology, University Clinic of Navarra, Pamplona, Spain

Ana Isabel Terleira-Fernández3 Department of Clinical Pharmacology, Hospital Clínico, Madrid, Spain;4 Department of Pharmacology, Universidad Complutense, Madrid, Spain

Emilio Vargas-Castrillón3 Department of Clinical Pharmacology, Hospital Clínico, Madrid, Spain;4 Department of Pharmacology, Universidad Complutense, Madrid, Spain

Pages 627-639 | Published online: 07 Nov 2014

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Correa Lara Maximiliano, García Chavez Jaime & Martinez Hernandez Erika. (2023) Rivaroxaban plus aspirin versus acenocoumarol to manage recurrent venous thromboembolic events despite systemic anticoagulation with rivaroxaban. Thrombosis Research 222, pages 43-48.
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Keiichi Hirono, Shinya Takarada, Nariaki Miyao, Hideyuki Nakaoka, Keijiro Ibuki, Sayaka Ozawa, Hideki Origasa & Fukiko Ichida. (2022) Thromboembolic events in left ventricular non-compaction: comparison between children and adults – a systematic review and meta-analysis. Open Heart 9:1, pages e001908.
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F. Couturaud, A.-M. Fischer, S. Laporte & O. Sanchez. (2021) Quelles sont les modalités du traitement anticoagulant initial d’une embolie pulmonaire et d’une thrombose veineuse profonde proximale ?. Revue des Maladies Respiratoires 38, pages e41-e52.
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Thomas L. Ortel, Ignacio NeumannWalter AgenoRebecca Beyth, Nathan P. Clark, Adam Cuker, Barbara A. Hutten, Michael R. Jaff, Veena Manja, Sam SchulmanCaitlin ThurstonSuresh VedanthamPeter VerhammeDaniel M. Witt, Ivan D. Florez, Ariel Izcovich, Robby NieuwlaatStephanie RossHolger J. Schünemann, Wojtek Wiercioch, Yuan ZhangYuqing Zhang. (2020) American Society of Hematology 2020 guidelines for management of venous thromboembolism: treatment of deep vein thrombosis and pulmonary embolism. Blood Advances 4:19, pages 4693-4738.
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C. Hoffmann, C. Leven, R. Le Mao, C. De Moreuil & K. Lacut. (2020) Anticoagulants oraux directs : dans quelles indications ? Lequel prescrire ? Pour ou contre chez les personnes fragiles et dans les situations atypiques ? Quelle surveillance et gestion des accidents hémorragiques ?. La Revue de Médecine Interne 41:9, pages 598-606.
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John A. Saunders, Whitney L. Gustafson, Sara R. Vazquez, Aubrey E. Jones & Daniel M. Witt. (2019) Real-world assessment of off-label direct oral anticoagulant dosing for venous thromboembolism. Journal of Thrombosis and Thrombolysis 48:3, pages 506-510.
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Liliana Villari, Roberta Pancani, Ferruccio Aquilini, Letizia Marconi, Laura Carrozzi, Antonio Palla & Alessandro Celi. (2018) Role of perfusion defects at follow-up lung scan in predicting recurrences after a first episode of symptomatic pulmonary embolism. Blood Coagulation & Fibrinolysis 29:1, pages 75-80.
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Zi Li & Jiangdong Ni. (2017) Role of microRNA‑26a in the diagnosis of lower extremity deep vein thrombosis in patients with bone trauma. Experimental and Therapeutic Medicine.
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Luis Miguel Salmerón Febres & Jorge Cuenca Manteca. (2017) Direct Oral Anticoagulants in the Treatment of Venous Thromboembolic Disease. Annals of Vascular Surgery 42, pages 337-350.
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Sébastien Gaertner, Elena-Mihaela Cordeanu, Salah Nouri, Alix-Marie Faller, Anne-Sophie Frantz, Corina Mirea, Pascal Bilbault, Patrick Ohlmann, Isabelle Le Ray & Dominique Stephan. (2017) Rivaroxaban versus standard anticoagulation for symptomatic venous thromboembolism (REMOTEV observational study): Analysis of 6-month outcomes. International Journal of Cardiology 226, pages 103-109.
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Lawrence Gibbs, Josiah Moulton & Vincent Tichenor. 2017. Family Medicine. Family Medicine 1041 1050 .

Stacey Knight, Raymond O. McCubrey, Zhong Yuan, Scott C. Woller, Benjamin D. Horne, T. Jared Bunch, Viet T. Le, Roger M. Mills & Joseph B. Muhlestein. (2016) Adverse cardiovascular events in acute coronary syndrome with indications for anticoagulation. Therapeutic Advances in Cardiovascular Disease 10:4, pages 231-241.
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Shannon W. Finks, Toby C. Trujillo & Paul P. Dobesh. (2016) Management of Venous Thromboembolism. Annals of Pharmacotherapy 50:6, pages 486-501.
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Đorđe Radak, Nenad Đukić, Mihailo Nešković, Srđan Babić, Slobodan Tanasković, Petar Popov & Predrag Gajin. (2016) Rivaroxaban versus Dabigatran: A new era in venous thromboembolism treatment. Medicinska istrazivanja 50:2, pages 14-18.
Crossref

Antonio Gómez-Outes, Mª Luisa Suárez-Gea, Ramón Lecumberri, Ana Isabel Terleira-Fernández & Emilio Vargas-Castrillón. (2015) Direct-acting oral anticoagulants: pharmacology, indications, management, and future perspectives. European Journal of Haematology 95:5, pages 389-404.
Crossref

Matt Shirley & Sohita Dhillon. (2015) Edoxaban: A Review in Deep Vein Thrombosis and Pulmonary Embolism. Drugs 75:17, pages 2025-2034.
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Mashio Nakamura, Masakatsu Nishikawa, Issei Komuro, Isao Kitajima, Yoshio Uetsuka, Takuji Yamagami, Hiroki Minamiguchi, Rika Yoshimatsu, Kosuke Tanabe, Nobushige Matsuoka, Kazuhiro Kanmuri & Hisao Ogawa. (2015) Apixaban for the Treatment of Japanese Subjects With Acute Venous Thromboembolism (AMPLIFY-J Study). Circulation Journal 79:6, pages 1230-1236.
Crossref

Lawrence Gibbs, Josiah Moulton & Vincent Tichenor. 2014. Family Medicine. Family Medicine 1 11 .

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Direct oral anticoagulants in the treatment of venous thromboembolism, with a focus on patients with pulmonary embolism: an evidence-based review

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Direct oral anticoagulants in the treatment of venous thromboembolism, with a focus on patients with pulmonary embolism: an evidence-based review

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