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Review

Neurogenic orthostatic hypotension in Parkinson’s disease: evaluation, management, and emerging role of droxidopa

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Pages 169-176 | Published online: 03 Apr 2014

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (5)

Stuart H Isaacson, Sagari Betté & Rajesh Pahwa. (2022) Istradefylline for OFF Episodes in Parkinson’s Disease: A US Perspective of Common Clinical Scenarios. Degenerative Neurological and Neuromuscular Disease 12, pages 97-109.
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Dinkar Kulshreshtha, Jacky Ganguly & Mandar Jog. (2020) Managing autonomic dysfunction in Parkinson’s disease: a review of emerging drugs. Expert Opinion on Emerging Drugs 25:1, pages 37-47.
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Debashis Biswas, Beverly Karabin & Debra Turner. (2019) Role of nurses and nurse practitioners in the recognition, diagnosis, and management of neurogenic orthostatic hypotension: a narrative review. International Journal of General Medicine 12, pages 173-184.
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Pearl K Jones, Brett H Shaw & Satish R Raj. (2015) Orthostatic hypotension: managing a difficult problem. Expert Review of Cardiovascular Therapy 13:11, pages 1263-1276.
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Peter Norman. (2015) Orphan drug approvals of 2014: Europe and the United States. Expert Opinion on Orphan Drugs 3:4, pages 445-455.
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Articles from other publishers (27)

Kenneth R. Dalton, Charles J. Kidd & Nawaz Hack. (2023) Toxin Induced Parkinsonism and Hospitalization Related Adverse Outcome Mitigation for Parkinson’s Disease: A Comprehensive Review. Journal of Clinical Medicine 12:3, pages 1074.
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Paola Polverino, Miloš Ajčević, Mauro Catalan, Claudio Bertolotti, Giovanni Furlanis, Alessandro Marsich, Alex Buoite Stella, Agostino Accardo & Paolo Manganotti. (2022) Comprehensive telemedicine solution for remote monitoring of Parkinson’s disease patients with orthostatic hypotension during COVID-19 pandemic. Neurological Sciences 43:6, pages 3479-3487.
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Stuart H. Isaacson, Khashayar Dashtipour, Ali A. Mehdirad & Amanda C. Peltier. (2021) Management Strategies for Comorbid Supine Hypertension in Patients with Neurogenic Orthostatic Hypotension. Current Neurology and Neuroscience Reports 21:4.
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Amy OrellanaAmy Orellana. 2021. Betätigungsorientierte Ergotherapie bei Morbus Parkinson. Betätigungsorientierte Ergotherapie bei Morbus Parkinson 129 216 .
Parisa Torabi, Fabrizio Ricci, Viktor Hamrefors, Richard Sutton & Artur Fedorowski. (2020) Classical and Delayed Orthostatic Hypotension in Patients With Unexplained Syncope and Severe Orthostatic Intolerance. Frontiers in Cardiovascular Medicine 7.
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Yoshiki Hase, Tuomo M. Polvikoski, Michael J. Firbank, Lucinda J. L. Craggs, Emily Hawthorne, Charlotte Platten, William Stevenson, Vincent Deramecourt, Clive Ballard, Rose Anne Kenny, Robert H. Perry, Paul Ince, Roxana O. Carare, Louise M. Allan, Karen Horsburgh & Raj N. Kalaria. (2019) Small vessel disease pathological changes in neurodegenerative and vascular dementias concomitant with autonomic dysfunction. Brain Pathology 30:1, pages 191-202.
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Gay R. Holstein. 2020. The Senses: A Comprehensive Reference. The Senses: A Comprehensive Reference 432 444 .
Manal Mohammed & Sattam Khulaif Alenezi. 2020. Principles of Neurochemistry. Principles of Neurochemistry 157 170 .
Kannayiram Alagiakrishnan. 2020. Hypotensive Syndromes in Geriatric Patients. Hypotensive Syndromes in Geriatric Patients 157 166 .
Jeremy K. Cutsforth-Gregory & Phillip A. Low. (2019) Neurogenic Orthostatic Hypotension in Parkinson Disease: A Primer. Neurology and Therapy 8:2, pages 307-324.
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Chand Raza, Rabia Anjum & Noor ul Ain Shakeel. (2019) Parkinson's disease: Mechanisms, translational models and management strategies. Life Sciences 226, pages 77-90.
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Zyta B. Wojszel, A. Kasiukiewicz & L. Magnuszewski. (2019) Health and Functional Determinants of Orthostatic Hypotension in Geriatric Ward Patients: A Retrospective Cross Sectional Cohort Study. The journal of nutrition, health & aging 23:6, pages 509-517.
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Daniel O. Claassen, Charles H. Adler, L. Arthur Hewitt & Christopher Gibbons. (2018) Characterization of the symptoms of neurogenic orthostatic hypotension and their impact from a survey of patients and caregivers. BMC Neurology 18:1.
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Siranan Klanbut, Siripan Phattanarudee, Supakit Wongwiwatthananukit, Chuthamanee Suthisisang & Roongroj Bhidayasiri. (2018) Symptomatic orthostatic hypotension in Parkinson's disease patients: Prevalence, associated factors and its impact on balance confidence. Journal of the Neurological Sciences 385, pages 168-174.
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Puneet Sharma & Ilse S. Pienaar. 2018. Molecular-Genetic and Statistical Techniques for Behavioral and Neural Research. Molecular-Genetic and Statistical Techniques for Behavioral and Neural Research 565 596 .
Orlando Graziani Povoas Barsottini, Carolina de Oliveira Souza, Giovana Diaferia & Alberto J. Espay. 2017. Movement Disorders Rehabilitation. Movement Disorders Rehabilitation 45 65 .
Ellen Merete Hagen & Judith Navarro-Otano. 2017. Bedside Approach to Autonomic Disorders. Bedside Approach to Autonomic Disorders 37 66 .
Dimitrios E. Iakovakis, Fotini A. Papadopoulou & Leontios J. Hadjileontiadis. (2016) Fuzzy logic‐based risk of fall estimation using smartwatch data as a means to form an assistive feedback mechanism in everyday living activities. Healthcare Technology Letters 3:4, pages 263-268.
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Ingrid Pretzer-Aboff, Lisette Bunting-Perry & Meredith Spindler. (2016) The Implications of Parkinson's Disease for Women's Health. Journal of Obstetric, Gynecologic & Neonatal Nursing 45:5, pages 723-736.
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Maria Eliza Freitas & Susan H Fox. (2016) Nondopaminergic treatments for Parkinson's disease: current and future prospects. Neurodegenerative Disease Management 6:3, pages 249-268.
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Dong In Sinn & Christopher H. Gibbons. (2016) Pathophysiology and Treatment of Orthostatic Hypotension in Parkinsonian Disorders. Current Treatment Options in Neurology 18:6.
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Ahmed Elgebaly, Bassant Abdelazeim, Omar Mattar, Mohamed Gadelkarim, Rehab Salah & Ahmed Negida. (2016) Meta-analysis of the safety and efficacy of droxidopa for neurogenic orthostatic hypotension. Clinical Autonomic Research 26:3, pages 171-180.
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Ilona Csoti, Wolfgang H. Jost & Heinz Reichmann. (2015) Parkinson’s disease between internal medicine and neurology. Journal of Neural Transmission 123:1, pages 3-17.
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Katherine E. McDonell, Cyndya A. Shibao & Daniel O. Claassen. (2015) Clinical Relevance of Orthostatic Hypotension in Neurodegenerative Disease. Current Neurology and Neuroscience Reports 15:12.
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Kannayiram Alagiakrishnan. (2015) Current Pharmacological Management of Hypotensive Syndromes in the Elderly. Drugs & Aging 32:5, pages 337-348.
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Ashley M. Fortress, Eric D. Hamlett, Elena M. Vazey, Gary Aston-Jones, Wayne A. Cass, Heather A. Boger & Ann-Charlotte E. Granholm. (2015) Designer Receptors Enhance Memory in a Mouse Model of Down Syndrome. The Journal of Neuroscience 35:4, pages 1343-1353.
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Carlos Henrique Ferreira Camargo, Eduardo Antunes Martins, Marcos Christiano Lange, Henrique Alvaro Hoffmann, Jissa Jeanete Luciano, Marcelo Rezende Young Blood, Marcelo Derbli Schafranski, Marcelo Machado Ferro & Edmar Miyoshi. (2015) Abnormal Cerebrovascular Reactivity in Patients with Parkinson’s Disease. Parkinson's Disease 2015, pages 1-5.
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