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Review

A clinical approach to obstructive sleep apnea as a risk factor for cardiovascular disease

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Pages 85-103 | Published online: 21 Mar 2016

Keep up to date with the latest research on this topic with citation updates for this article.

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Mintesnot Tenkir Teni, Travis Loux & Anne Sebert Kuhlmann. (2022) Racial disparity in gestational diabetes mellitus and the association with sleep-disordered breathing and smoking cigarettes: a cross-sectional study. The Journal of Maternal-Fetal & Neonatal Medicine 35:26, pages 10601-10607.
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Serpil Yazgan, Fatma Erboy, Haci Ugur Celik, Tacettin Ornek, Suat Hayri Ugurbas, Firuzan Kokturk, Orhan Ayar, Mehmet Orcun Akdemir & Erkan Celik. (2017) Peripapillary Choroidal Thickness and Retinal Nerve Fiber Layer in Untreated Patients with Obstructive Sleep Apnea-Hypopnea Syndrome: A Case–Control Study. Current Eye Research 42:11, pages 1552-1560.
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Jacqueline K. Limberg, Sarah E. Baker, Humphrey G. Petersen-Jones, Winston Guo, An Huang, Michael D. Jensen & Prachi Singh. (2022) Endothelin-1 as a novel target for the prevention of metabolic dysfunction with intermittent hypoxia in male participants. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 323:3, pages R351-R362.
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Maurice Moser, Florent Baty, Martin H. Brutsche & Otto D. Schoch. (2022) In-hospital survival paradox in patients with sleep apnea—A nation-wide nested case-control study. PLOS ONE 17:7, pages e0271004.
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Bruno G. Durante, Rosyvaldo Ferreira-Silva, Thiago T. Goya, Marta F. Lima, Ana Clara T. Rodrigues, Luciano F. Drager, Camila P. Jordão, Amanda G. Rodrigues, Maria Janieire de Nazare N. Alves, Geraldo Lorenzi-Filho, Carlos E. Negrão & Linda M. Ueno-Pardi. (2022) Effects of Exercise Training on Left Ventricular Diastolic Function Markers in Patients with Obstructive Sleep Apnea: A Randomized Study. International Journal of Cardiovascular Sciences.
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Ozaifa Kareem, Masood Tanvir & G. N. Bader. (2022) Obstructive Sleep Apnea and Metabolic Syndrome. Sleep and Vigilance 6:1, pages 85-99.
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Saikrishna C. Gourishetti, Rodney TaylorAmal Isaiah. (2021) Stratifying the Risk of Cardiovascular Disease in Obstructive Sleep Apnea Using Machine Learning. The Laryngoscope 132:1, pages 234-241.
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M. Serino, C. Cardoso, R.J. Carneiro, J. Ferra, F. Aguiar, D. Rodrigues, M. Redondo, M. van Zeller & M. Drummond. (2021) OSA patients not treated with PAP - Evolution over 5 years according to the Baveno classification and cardiovascular outcomes. Sleep Medicine 88, pages 1-6.
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Michael R. Le Grande, Alun C. Jackson, Alison Beauchamp, Debra Kerr & Andrea Driscoll. (2021) Diagnostic accuracy and suitability of instruments that screen for obstructive sleep apnoea, insomnia and sleep quality in cardiac patients: a meta-analysis. Sleep Medicine 86, pages 135-160.
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Micha T. Maeder. (2021) Editorial Commentary: Biomarkers of cardiovascular risk in obstructive sleep apnea – innovation or illusion?. Trends in Cardiovascular Medicine 31:4, pages 250-251.
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Samantha Y. Starkey, Daniel R. Jonasson, Stephanie Alexis, Susan Su, Ravinder Johal, Paul Sweeney, Penelope M.A. Brasher, John Fleetham, Najib Ayas, Teddi Orenstein & Iqbal H. Ahmed. (2021) Screening for Obstructive Sleep Apnea in an Atrial Fibrillation Population: What’s the Best Test?. CJC Open 3:4, pages 442-449.
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Chia-Min Chen, Chia-Yu Kuo, Meng-Ni Wu, Jen-Yu Hung, Chung-Yao Hsu & Ming-Ju Tsai. (2021) Increased risk of major depressive disorder in sleep apnea patients in Taiwan. Scientific Reports 11:1.
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Mohammed Bukhari, Meshal Alghtani, Ziyad Aljohani, Abdullah Qasem & Ibrahim Alhazmi. (2021) Diagnosis and treatment of sleep disorders: a brief review. International Journal of Medicine in Developing Countries, pages 364-369.
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Fabienne L. Huber, Michael Furian, Malcolm Kohler, Tsogyal D. Latshang, Yvonne Nussbaumer-Ochsner, Alexander Turk, Otto D. Schoch, Irene Laube, Robert Thurnheer & Konrad E. Bloch. (2021) Health Preference Measures in Patients with Obstructive Sleep Apnea Syndrome Undergoing Continuous Positive Airway Pressure Therapy: Data from a Randomized Trial. Respiration 100:4, pages 328-338.
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Josip Lesko, Nikolina Obradović & Vana Turudić. 2021. CMBEBIH 2021. CMBEBIH 2021 601 608 .
P. E. Opolonskaya, N. I. Maximov & M Yu. Smetanin. (2020) Effect of obstructive sleep apnea syndrome on left ventricular remodeling in acute ST-elevation myocardial infarction after percutaneous coronary intervention. The Siberian Journal of Clinical and Experimental Medicine 35:3, pages 100-106.
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Hong Wang, Xinxin Li, Zhangui Tang & Guoping Gong. (2020) Cardiovascular Outcomes Post Percutaneous Coronary Intervention in Patients with Obstructive Sleep Apnea and Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis. Diabetes Therapy 11:8, pages 1795-1806.
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Sema Saraç & Gulgun Cetintaş Afsar. (2019) Effect of mean apnea-hypopnea duration in patients with obstructive sleep apnea on clinical and polysomnography parameter. Sleep and Breathing 24:1, pages 77-81.
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Henrik Jonathan Münch, Padraig O'Leary, Jesper Bille & Thomas Kjaergaard. (2020) Oropharyngeal rhabdomyoma: the cause of severe sleep apnoea?. BMJ Case Reports 13:2, pages e230949.
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S. Schulz, J. Ritter, G. Schneider, O. Guntinas-Lichius & A. Voss. (2019) Risk detection in patients with obstructive sleep apnea syndrome based on cardiovascular time series analysis. Risk detection in patients with obstructive sleep apnea syndrome based on cardiovascular time series analysis.
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Milena K. Pavlova & Véronique Latreille. (2019) Sleep Disorders. The American Journal of Medicine 132:3, pages 292-299.
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Leonie Biener, Carmen Pizarro, Georg Nickenig & Dirk Skowasch. (2019) Obstructive sleep apnea and atherosclerosis—update 2019Obstruktive Schlafapnoe und Arteriosklerose – Update 2019. Somnologie 23:1, pages 3-7.
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Cesare Cuspidi, Carla Sala, Marijana Tadic & Guido Grassi. (2019) When Office Blood Pressure Is Not Enough: The Case of Masked Hypertension. American Journal of Hypertension 32:3, pages 225-233.
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Catherine M. Spagnuolo, Michael McIsaac, James Dosman, Chandima Karunanayake, Punam Pahwa & William Pickett. (2019) Distance to Specialist Medical Care and Diagnosis of Obstructive Sleep Apnea in Rural Saskatchewan. Canadian Respiratory Journal 2019, pages 1-14.
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Jae Hoon Lee, Eun-Ju Kang, Woo Yong Bae, Jong Kuk KimJae Hyung ChoiChul Hoon KimSang Joon KimKyoo Sang JoMoon Sung KimTae Kyung Koh. (2019) Carotid Arterial Calcium Scoring Using Upper Airway Computed Tomography in Patients with Obstructive Sleep Apnea: Efficacy as a Clinical Predictor of Cerebrocardiovascular Disease. Korean Journal of Radiology 20:4, pages 631.
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Asmaa M. Abumuamar, Paul Dorian, David Newman & Colin M. Shapiro. (2018) The STOP-BANG questionnaire shows an insufficient specificity for detecting obstructive sleep apnea in patients with atrial fibrillation. Journal of Sleep Research 27:6, pages e12702.
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Ai-Ping Chua, Chieh-Yang Koo, William Kristanto, Maria Victoria Jane Macalalag Parot, Eugene Siang-Joo Tan, Esther Hui-Ting Koh, Munirah Binte Abd Gani, Pipin Kojodjojo, Tun-Oo Han, Siew-Pang Chan, Jenny Pek-Ching Chong, Christopher Frampton, Arthur Mark Richards & Chi-Hang Lee. (2018) Sleep study-guided multidisciplinary therapy (SGMT) for patients with acute coronary syndrome: Trial rationale and design. Clinical Cardiology 41:6, pages 721-728.
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Katelynn M. Wilton, Eric L. Matteson & Cynthia S. Crowson. (2018) Risk of Obstructive Sleep Apnea and Its Association with Cardiovascular and Noncardiac Vascular Risk in Patients with Rheumatoid Arthritis: A Population-based Study. The Journal of Rheumatology 45:1, pages 45-52.
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Denis Monneret. (2019) N-terminal pro-brain natriuretic peptide: a potential follow-up biomarker of mandibular advancement device efficacy on cardiac function in obstructive sleep apnea. F1000Research 7, pages 1818.
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Cesare Cuspidi, Carla Sala, Marijana Tadic & Guido Grassi. 2018. Disorders of Blood Pressure Regulation. Disorders of Blood Pressure Regulation 663 673 .
Yanhua Li, Shanshan Yang, Si Chen, Xinhong Guo & Yundai Chen. (2017) Patients with symptoms and characteristics consistent with obstructive sleep apnea are at a higher risk for acute and subacute stent thrombosis after percutaneous coronary stent implantation: a single-center case–control study. BMC Cardiovascular Disorders 17:1.
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Lars Eichhorn, Ramona Dolscheid‐Pommerich, Felix Erdfelder, Muhammad Ajmal Ayub, Theresa Schmitz, Nikos Werner & Felix Jansen. (2017) Sustained apnea induces endothelial activation. Clinical Cardiology 40:9, pages 704-709.
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Kun Li, Peng Wei, Yanwen Qin & Yongxiang Wei. (2017) Is C-reactive protein a marker of obstructive sleep apnea?. Medicine 96:19, pages e6850.
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Ronaldo D. Piovezan, Camila Kase, Renato Moizinho, Sergio Tufik & Dalva Poyares. (2017) Gabapentin acutely increases the apnea-hypopnea index in older men: data from a randomized, double-blind, placebo-controlled study. Journal of Sleep Research 26:2, pages 166-170.
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Jin-Wei Wang, Ai-Ying Li, Qiu-Hong Guo, Ya-jing Guo, James W. Weiss & En-Sheng Ji. (2017) Endothelin-1 and ET receptors impair left ventricular function by mediated coronary arteries dysfunction in chronic intermittent hypoxia rats. Physiological Reports 5:1, pages e13050.
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Claudio Liguori, Francesca Izzi, Nicola Biagio Mercuri, Andrea Romigi, Alberto Cordella, Umberto Tarantino & Fabio Placidi. (2017) Vitamin D status of male OSAS patients improved after long-term CPAP treatment mainly in obese subjects. Sleep Medicine 29, pages 81-85.
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Micha T. Maeder, Christian Mueller, Otto D. Schoch, Peter Ammann & Hans Rickli. (2016) Biomarkers of cardiovascular stress in obstructive sleep apnea. Clinica Chimica Acta 460, pages 152-163.
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