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Review

Medical databases in studies of drug teratogenicity: methodological issues

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Pages 37-43 | Published online: 25 Mar 2010

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Anne-Mette B Bjørn, Rikke B Nielsen, Mette Nørgaard, Ellen A Nohr & Vera Ehrenstein. (2013) Risk of miscarriage among users of corticosteroid hormones: a population-based nested case-control study. Clinical Epidemiology 5, pages 287-294.
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Henrik Toft Sørensen. (2012) Editor’s choice. Clinical Epidemiology 4, pages 157-158.
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Sigrun Alba Johannesdottir, Merete Lund Mægbæk, Jens Georg Hansen, Timothy L Lash, Lars Pedersen & Vera Ehrenstein. (2012) Correspondence between general practitioner-reported medication use and timing of prescription dispensation. Clinical Epidemiology 4, pages 13-18.
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Anne-Mette Bay Bjørn, Mette Nørgaard, Heidi Holmager Hundborg, Ellen Aagaard Nohr & Vera Ehrenstein. (2011) Use of prescribed drugs among primiparous women: an 11-year population-based study in Denmark. Clinical Epidemiology 3, pages 149-156.
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Elena Dudukina, Szimonetta Komjáthiné Szépligeti, Pär Karlsson, Kofi Asomaning, Anne Kjersti Daltveit, Katja Hakkarainen, Fabian Hoti, Helle Kieler, Astrid Lunde, Ingvild Odsbu, Matti Rantanen, Johan Reutfors, Laura Saarelainen, Vera Ehrenstein & Gunnar Toft. (2023) Prenatal exposure to pregabalin, birth outcomes and neurodevelopment – a population-based cohort study in four Nordic countries. Drug Safety 46:7, pages 661-675.
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Jiehua Wei, Fan Xia, Junxiang Miao, Tingting Wang, Lizhang Chen & Xuemei Yan. (2022) The risk of congenital heart defects associated with corticosteroids use during the first trimester of pregnancy: a systematic review and meta-analysis. European Journal of Clinical Pharmacology 79:1, pages 1-11.
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Young Min Hur, Jiwon Choi, Sunwha Park, Sarah Soyeon Oh & Young Ju Kim. (2022) Prenatal maternal alcohol exposure: diagnosis and prevention of fetal alcohol syndrome. Obstetrics & Gynecology Science 65:5, pages 385-394.
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Daniel Marques Mota, Álvaro Vigo & Ricardo de Souza Kuchenbecker. (2021) Formulários de notificação de reações adversas a medicamento nos sistemas de farmacovigilância do Brasil e outros doze países latino-americanos: análise comparativa. Ciência & Saúde Coletiva 26:4, pages 1245-1257.
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Ali Zarrinpar, Ting-Yuan David Cheng & Zhiguang Huo. (2020) What Can We Learn About Drug Safety and Other Effects in the Era of Electronic Health Records and Big Data That We Would Not Be Able to Learn From Classic Epidemiology?. Journal of Surgical Research 246, pages 599-604.
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Lars Pedersen, Kenneth R. Petronis, Mette Nørgaard, Jingping Mo, Trine Frøslev, Olof Stephansson, Fredrik Granath, Helle Kieler & Henrik Toft Sørensen. (2019) Risk of adverse birth outcomes after maternal varenicline use: A population‐based observational study in Denmark and Sweden. Pharmacoepidemiology and Drug Safety 29:1, pages 94-102.
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Guillermo Prada-Ramallal, Bahi Takkouche & Adolfo Figueiras. (2019) Bias in pharmacoepidemiologic studies using secondary health care databases: a scoping review. BMC Medical Research Methodology 19:1.
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Yusuf Cem Kaplan, Jonathan Luke Richardson, Elif Keskin-Arslan, Hilal Erol-Coskun & Debra Kennedy. (2019) Use of ondansetron during pregnancy and the risk of major congenital malformations: A systematic review and meta-analysis. Reproductive Toxicology 86, pages 1-13.
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Konstantin A. Lutsevich & Olga V. Reshetko. (2019) Federation Pharmacological Safety in Pregnancy: Modern Knowledge, Practice and Pharmacoepidemiological Approaches to the Studying and Recognizing of Drugs with Teratogenic Risk. Pediatric pharmacology 16:1, pages 19-29.
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Selin Acar, Elif Keskin-Arslan, Hilal Erol-Coskun, Tijen Kaya-Temiz & Yusuf Cem Kaplan. (2019) Pregnancy outcomes following quinolone and fluoroquinolone exposure during pregnancy: A systematic review and meta-analysis. Reproductive Toxicology 85, pages 65-74.
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Yusuf Cem Kaplan & Hilal Erol-Coskun. 2019. Perinatal Psychopharmacology. Perinatal Psychopharmacology 37 53 .
Shan-Yan Gao, Qi-Jun Wu, Ce Sun, Tie-Ning Zhang, Zi-Qi Shen, Cai-Xia Liu, Ting-Ting Gong, Xin Xu, Chao Ji, Dong-Hui Huang, Qing Chang & Yu-Hong Zhao. (2018) Selective serotonin reuptake inhibitor use during early pregnancy and congenital malformations: a systematic review and meta-analysis of cohort studies of more than 9 million births. BMC Medicine 16:1.
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Mollie E. Wood, Stavroula Chrysanthopoulou, Hedvig M.E. Nordeng & Kate L. Lapane. (2018) The Impact of Nondifferential Exposure Misclassification on the Performance of Propensity Scores for Continuous and Binary Outcomes. Medical Care 56:8, pages e46-e53.
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Olga V. Reshetko, Konstantin A. Lutsevich & Irina I. Sanina. (2017) Pharmacological Safety in Pregnancy: A Systematic Review On the Use of Potentially Teratogenic Drugs. Pediatric pharmacology 14:2, pages 127-141.
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Yusuf C. Kaplan, Elif Keskin-Arslan, Selin Acar & Kaan Sozmen. (2016) Prenatal selective serotonin reuptake inhibitor use and the risk of autism spectrum disorder in children: A systematic review and meta-analysis. Reproductive Toxicology 66, pages 31-43.
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Sherif Eltonsy, Brigitte Martin, Ema Ferreira & Lucie Blais. (2016) Systematic procedure for the classification of proven and potential teratogens for use in research. Birth Defects Research Part A: Clinical and Molecular Teratology 106:4, pages 285-297.
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Anne-Mette Bay Bjørn, Vera Ehrenstein, Ellen Aagaard Nohr & Mette Nørgaard. (2015) Use of Inhaled and Oral Corticosteroids in Pregnancy and the Risk of Malformations or Miscarriage. Basic & Clinical Pharmacology & Toxicology 116:4, pages 308-314.
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Elisabeth Svensson, Vera Ehrenstein, Mette Nørgaard, Leiv Sigmund Bakketeig, Kenneth J. Rothman, Henrik Toft Sørensen & Lars Pedersen. (2014) Estimating the Proportion of All Observed Birth Defects Occurring in Pregnancies Terminated by a Second-trimester Abortion. Epidemiology 25:6, pages 866-871.
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Rachel A. Charlton, Amanda J. Neville, Sue Jordan, Anna Pierini, Christine Damase‐Michel, Kari Klungsøyr, Anne‐Marie Nybo Andersen, Anne Vinkel Hansen, Rosa Gini, Jens H. J. Bos, Aurora Puccini, Caroline Hurault‐Delarue, Caroline J. Brooks, Lolkje T. W. Jong‐van den Berg & Corinne S. Vries. (2014) Healthcare databases in Europe for studying medicine use and safety during pregnancy. Pharmacoepidemiology and Drug Safety 23:6, pages 586-594.
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Christina D. Chambers & Elizabeth B. Andrews. 2014. Mann's Pharmacovigilance. Mann's Pharmacovigilance 611 624 .
Natalie Gavrielov-Yusim & Michael Friger. (2014) Use of administrative medical databases in population-based research: Table 1. Journal of Epidemiology and Community Health 68:3, pages 283-287.
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Anne-Mette Bay Bjørn, Vera Ehrenstein, Heidi Holmager Hundborg, Ellen Aagaard Nohr, Henrik Toft Sørensen & Mette Nørgaard. (2014) Use of Corticosteroids in Early Pregnancy is Not Associated With Risk of Oral Clefts and Other Congenital Malformations in Offspring. American Journal of Therapeutics 21:2, pages 73-80.
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E. Elefant. (2014) Aspects méthodologiques de l’évaluation des médicaments tératogènes dans l’espèce humaineTeratogenic risk assessment of drugs in humans: Methodological aspects. Revue de médecine périnatale 6:1, pages 3-11.
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Youn-Jung Kim, Jina Lee, Mi-Kyung Song, Taejun Han & Jae-Chun Ryu. (2013) Valproic acid inhibits cell size and cell proliferation by AMPK-mediated mTOR signaling pathway in JEG-3 cells. BioChip Journal 7:3, pages 267-277.
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Ulrika Nörby, Karin Källén, Birgit Eiermann, Seher Korkmaz, Birger Winbladh & Lars L. Gustafsson. (2012) Drugs and Birth Defects: a knowledge database providing risk assessments based on national health registers. European Journal of Clinical Pharmacology 69:4, pages 889-899.
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Luke E. Grzeskowiak, Andrew L. Gilbert & Janna L. Morrison. (2012) Methodological challenges in using routinely collected health data to investigate long-term effects of medication use during pregnancy. Therapeutic Advances in Drug Safety 4:1, pages 27-37.
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Simon H. L. Thomas & Laura M. Yates. (2012) Prescribing without evidence - pregnancy. British Journal of Clinical Pharmacology 74:4, pages 691-697.
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Jan M. Friedman. (2012) ABCDXXX: The obscenity of postmarketing surveillance for teratogenic effects. Birth Defects Research Part A: Clinical and Molecular Teratology 94:8, pages 670-676.
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Mark W. Green, John D. Seeger, Craig Peterson & Arun Bhattacharyya. (2012) Utilization of Topiramate During Pregnancy and Risk of Birth Defects. Headache: The Journal of Head and Face Pain 52:7, pages 1070-1084.
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Margaret P. Adam, Janine E. Polifka & J.M. Friedman. (2011) Evolving knowledge of the teratogenicity of medications in human pregnancy. American Journal of Medical Genetics Part C: Seminars in Medical Genetics 157:3, pages 175-182.
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Marte Gravseth Espnes, Tone Bjørge & Anders Engeland. (2011) Comparison of recorded medication use in the Medical Birth Registry of Norway with prescribed medicines registered in the Norwegian Prescription Database. Pharmacoepidemiology and Drug Safety 20:3, pages 243-248.
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Lyn Colvin, Linda Slack-Smith, Fiona J. Stanley & Carol Bower. (2011) Dispensing patterns and pregnancy outcomes for women dispensed selective serotonin reuptake inhibitors in pregnancy. Birth Defects Research Part A: Clinical and Molecular Teratology 91:3, pages 142-152.
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