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Review

Prevention of NSAID-related upper gastrointestinal toxicity: a meta-analysis of traditional NSAIDs with gastroprotection and COX-2 inhibitors

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Pages 47-71 | Published online: 28 Oct 2009

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María-José Domper Arnal, Gonzalo Hijos-Mallada & Angel Lanas. (2022) Gastrointestinal and cardiovascular adverse events associated with NSAIDs. Expert Opinion on Drug Safety 21:3, pages 373-384.
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Man Yang, Min He, Miao Zhao, Bing Zou, Jun Liu, Ling-Min Luo, Qiu-Lan Li, Jun-Hui He & Ping-Guang Lei. (2017) Proton pump inhibitors for preventing non-steroidal anti-inflammatory drug induced gastrointestinal toxicity: a systematic review. Current Medical Research and Opinion 33:6, pages 973-980.
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Gerhard Zingler, Birgit Hermann, Tim Fischer & Thomas Herdegen. (2016) Cardiovascular adverse events by non-steroidal anti-inflammatory drugs: when the benefits outweigh the risks. Expert Review of Clinical Pharmacology 9:11, pages 1479-1492.
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Luis Garegnani, Camila Micaela Escobar Liquitay, Miguel Puga-Tejada & Juan VA Franco. (2022) Proton pump inhibitors for the prevention of non-steroidal anti-inflammatory drug-induced ulcers and dyspepsia. Cochrane Database of Systematic Reviews 2022:5.
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George A Wells, Peter Tugwell, Gunnar Tomasson, Francis Guillemin, Lara J Maxwell, Beverley J Shea, Shawna Grosskleg, Peter A Merkel, Lyn March & Dorcas E Beaton. (2021) Composite outcomes at OMERACT: Multi-outcome domains and composite outcome domains. Seminars in Arthritis and Rheumatism 51:6, pages 1370-1377.
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L. Yu. Orekhova, E. S. Loboda, V. G. Atrushkevich, E. V. Kosova, V. Yu. Vashneva & A. A. Petrov. (2021) Relevance of non-steroidal anti-inflammatory drugs in periodontology. Parodontologiya 26:3, pages 211-222.
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Antigoni E. Koletti, Efstathia Tsarouchi, Afroditi Kapourani, Konstantinos N. Kontogiannopoulos, Andreana N. Assimopoulou & Panagiotis Barmpalexis. (2020) Gelatin nanoparticles for NSAID systemic administration: Quality by design and artificial neural networks implementation. International Journal of Pharmaceutics 578, pages 119118.
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Elisabeta ANTONESCU, Maria TOTAN & Sînziana Călina SILIȘTEANU. (2020) The quality of life - an indicator for assessing the recovery program in patients diagnosed with degenerative disorders. Balneo Research Journal:Vol.11, No1, pages 88-94.
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A. E. Karateev, E. V. Moroz & E. V. Kryukov. (2019) Small intestinal damage associated with the use of nonsteroidal anti-inflammatory drugs. Almanac of Clinical Medicine 47:6, pages 559-567.
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Lucija Kuna, Jelena Jakab, Robert Smolic, Nikola Raguz-Lucic, Aleksandar Vcev & Martina Smolic. (2019) Peptic Ulcer Disease: A Brief Review of Conventional Therapy and Herbal Treatment Options. Journal of Clinical Medicine 8:2, pages 179.
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Stanley L. Marks, Peter H. Kook, Mark G. Papich, M. K. Tolbert & Michael D. Willard. (2018) ACVIM consensus statement: Support for rational administration of gastrointestinal protectants to dogs and cats. Journal of Veterinary Internal Medicine 32:6, pages 1823-1840.
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Yuji Mizokami, Kazunori Oda, Nobuo Funao, Akira Nishimura, Satoshi Soen, Takashi Kawai, Kiyoshi Ashida & Kentaro Sugano. (2018) Vonoprazan prevents ulcer recurrence during long-term NSAID therapy: randomised, lansoprazole-controlled non-inferiority and single-blind extension study. Gut 67:6, pages 1042-1051.
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Charles Fokunang. (2018) Overview of non-steroidal anti-inflammatory drugs (nsaids) in resource limited countries. MOJ Toxicology 4:1.
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Angel Lanas & Francis K L Chan. (2017) Peptic ulcer disease. The Lancet 390:10094, pages 613-624.
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Luis Parada, Jens Pauli Marstein & Andrey Danilov. (2016) Tolerability of the COX-1/COX-2 inhibitor lornoxicam in the treatment of acute and rheumatic pain. Pain Management 6:5, pages 445-454.
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Mostafa Mohammadzadeh, Mohammad Sadegh Nourbakhsh, Elham Khodaverdi, Farzin Hadizadeh & Sina Omid Malayeri. (2016) Enhanced Loading and Release of Non-Steroidal Anti-Inflammatory Drugs from Silica-Based Nanoparticle Carriers. Chemical Biology & Drug Design 88:3, pages 370-379.
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Carmelo Scarpignato, Angel Lanas, Corrado Blandizzi, Willem F Lems, Matthias Hermann & Richard H Hunt. (2015) Safe prescribing of non-steroidal anti-inflammatory drugs in patients with osteoarthritis – an expert consensus addressing benefits as well as gastrointestinal and cardiovascular risks. BMC Medicine 13:1.
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Richard J.M. Ingram, Krish Ragunath & John C. Atherton. 2015. Yamada' s Textbook of Gastroenterology. Yamada' s Textbook of Gastroenterology 1032 1077 .
Roy D. Altman & Marc C. Hochberg. 2015. Rheumatology. Rheumatology 1508 1514 .
Ying He, Esther W. Chan, Kenneth K. C. Man, Wallis C. Y. Lau, Wai K. Leung, Lai M. Ho & Ian C. K. Wong. (2014) Dosage Effects of Histamine-2 Receptor Antagonist on the Primary Prophylaxis of Non-Steroidal Anti-Inflammatory Drug (NSAID)-Associated Peptic Ulcers: A Retrospective Cohort Study. Drug Safety 37:9, pages 711-721.
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E. V. Onuchina. (2014) Antiplatelet therapy with acetylsalicylic acid: Approaches to reducing the frequency of gastrointenstinal adverse reactions. Terapevticheskii arkhiv 86:12, pages 98.
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F. Navarro Sarabia & V. Moreira Navarrete. (2013) Estado actual del tratamiento de la artrosis. Medicine - Programa de Formación Médica Continuada Acreditado 11:46, pages 2741-2746.
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Anne-Marie Malfait & Thomas J. Schnitzer. (2013) Towards a mechanism-based approach to pain management in osteoarthritis. Nature Reviews Rheumatology 9:11, pages 654-664.
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Johanne Brooks, Richard Warburton & Ian L.P. Beales. (2013) Prevention of upper gastrointestinal haemorrhage: current controversies and clinical guidance. Therapeutic Advances in Chronic Disease 4:5, pages 206-222.
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G. M. C. Masclee, V. E. Valkhoff, E. M. van Soest, R. Schade, G. Mazzaglia, M. Molokhia, G. Trifirò, J. L. Goldstein, S. Hernández-Díaz, E. J. Kuipers & M. C. J. M. Sturkenboom. (2013) Cyclo-oxygenase-2 inhibitors or nonselective NSAIDs plus gastroprotective agents: what to prescribe in daily clinical practice?. Alimentary Pharmacology & Therapeutics 38:2, pages 178-189.
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Christian Jonasson, Jan G. Hatlebakk, Lars Lundell, Jukka P. Kouri, Morten Andersen & Fredrik Granath. (2013) Association between adherence to concomitant proton pump inhibitor therapy in current NSAID users and upper gastrointestinal complications. European Journal of Gastroenterology & Hepatology 25:5, pages 531-538.
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Paul Arnstein & Keela Herr. (2013) Risk Evaluation and Mitigation Strategies for Older Adults with Persistent Pain. Journal of Gerontological Nursing 39:4, pages 56-66.
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Patricia McGettigan & David Henry. (2013) Use of Non-Steroidal Anti-Inflammatory Drugs That Elevate Cardiovascular Risk: An Examination of Sales and Essential Medicines Lists in Low-, Middle-, and High-Income Countries. PLoS Medicine 10:2, pages e1001388.
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Carla J. Gargallo & Angel Lanas. (2013) Is NSAIDs-related gastrointestinal damage preventable?. Journal of Digestive Diseases 14:2, pages 55-61.
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Susan M. Miller. (2012) Low Back Pain. Primary Care: Clinics in Office Practice 39:3, pages 499-510.
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C. J. Hawkey & John C. Atherton. 2012. Textbook of Clinical Gastroenterology and Hepatology. Textbook of Clinical Gastroenterology and Hepatology 219 233 .
Marc C. Hochberg, Roy D. Altman, Karine Toupin April, Maria Benkhalti, Gordon Guyatt, Jessie McGowan, Tanveer Towheed, Vivian Welch, George Wells & Peter Tugwell. (2012) American College of Rheumatology 2012 recommendations for the use of nonpharmacologic and pharmacologic therapies in osteoarthritis of the hand, hip, and knee. Arthritis Care & Research 64:4, pages 465-474.
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Philip T. Ramsay & Aaron Carr. (2011) Gastric Acid and Digestive Physiology. Surgical Clinics of North America 91:5, pages 977-982.
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Angel Lanas, Ping Wu, Jennie Medin & Edward J. Mills. (2011) Low Doses of Acetylsalicylic Acid Increase Risk of Gastrointestinal Bleeding in a Meta-Analysis. Clinical Gastroenterology and Hepatology 9:9, pages 762-768.e6.
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Dáša Halamová, Mária Badaničová, Vladimír Zeleňák, Taťána Gondová & Ulla Vainio. (2010) Naproxen drug delivery using periodic mesoporous silica SBA-15. Applied Surface Science 256:22, pages 6489-6494.
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Alaa Rostom, Catherine Dube, George A Wells, Peter Tugwell, Vivian Welch, Emilie Jolicoeur, Jessie McGowan, Angel Lanas, Eleanor Rushton & Tushar Shukla. (2002) Prevention of NSAID-induced gastroduodenal ulcers. Cochrane Database of Systematic Reviews 2021:10.
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