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Epilepsy and suicide: pathogenesis, risk factors, and prevention

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Pages 365-370 | Published online: 11 Apr 2008

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Read on this site (3)

Milena Gandy, Louise Sharpe, Kathryn Nicholson Perry, Zoe Thayer, Laurie Miller, Janet Boserio & Armin Mohamed. (2014) Cognitive Behaviour Therapy to Improve Mood in People with Epilepsy: A Randomised Controlled Trial. Cognitive Behaviour Therapy 43:2, pages 153-166.
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Sherifa Ahmad Hamed. (2011) Psychiatric symptomatologies and disorders related to epilepsy and antiepileptic medications. Expert Opinion on Drug Safety 10:6, pages 913-934.
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Lior Givon, Steven Porter, Bharanidharan Padmanabhan, Jessica Goren & Pieter A. Cohen. (2011) Levetiracetam, Seizures, and Suicidality. Harvard Review of Psychiatry 19:1, pages 47-55.
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Articles from other publishers (35)

Stephanie K. Jones, Jeffrey E. Korte & Dulaney Wilson. (2023) Hazard of substance abuse onset among adults diagnosed with epilepsy or migraine. Epilepsy & Behavior 144, pages 109258.
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Elaine W. Pang, Nicholas D. Lawn, Judy Lee & John W. Dunne. (2023) Mortality after a first‐ever unprovoked seizure. Epilepsia 64:5, pages 1266-1277.
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Linnet Ongeri, Cyrus Theuri, Miriam Nyawira, Brenda W.J.H. Penninx, Joeri K. Tijdink, Symon M. Kariuki & Charles R.J.C. Newton. (2023) Risk of suicidality in mental and neurological disorders in low and middle-income countries: A systematic review and meta-analysis. Comprehensive Psychiatry 123, pages 152382.
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Gloria Maria de Almeida Souza Tedrus & Daniela de Carvalho Mendonça de Souza. (2022) I would be better off dead: investigating suicidal ideation in people with epilepsy. Arquivos de Neuro-Psiquiatria 80:07, pages 718-724.
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Mariacarolina Vacca, Mariana Fernandes, Matteo Spanetta, Fabio Placidi, Francesca Izzi, Caterina Lombardo, Nicola Biagio Mercuri & Claudio Liguori. (2021) Depressive symptoms in patients with epilepsy and clinically associated features in a single tertiary center. Neurological Sciences 43:3, pages 1965-1974.
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Girish Chandra Baniya & Kamala Verma. (2022) Prevalence of depression, risk factors, and quality of life in patients with epilepsy in a remote area of western Rajasthan. Epilepsy & Behavior 127, pages 108488.
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Temitope Ogundare. (2021) Depression in Patients with Epilepsy in Nigeria: Phenomenology and Predictors. International Journal of Epilepsy 7:01, pages 1-7.
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RM Bhoopathy, B Arthy, SS Vignesh, Smitha Ruckmani & AV Srinivasan. (2021) Involvement of Incomplete Hippocampal Inversion in Intractable Epilepsy: Evidence from Neuropsychological Studies. Neurology India 69:4, pages 842.
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Hrvoje Hećimović, Zvonimir Popović & Frank Gilliam. 2022. Psychiatric and Behavioral Aspects of Epilepsy. Psychiatric and Behavioral Aspects of Epilepsy 209 250 .
Tesfa Mekonen, Asmamaw Getnet, Amsalu Belete, Melak Menberu & Wubalem Fekadu. (2020) Suicidal behavior among people with epilepsy in Northwest Ethiopia: A comparative cross-sectional study. Epilepsy & Behavior 111, pages 107233.
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Tore Eid, Tih‐Shih W. Lee, Peter Patrylo & Hitten P. Zaveri. (2018) Astrocytes and Glutamine Synthetase in Epileptogenesis. Journal of Neuroscience Research 97:11, pages 1345-1362.
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Qian Li, Li-na Zhu, Hai-jiao Wang, Xu Lin, Da Xu, Deng Chen, Yu Zhang & Ling Liu. (2019) Validation of the Neurological Disorders Depression Inventory for Epilepsy (NDDIE) as a rapid suicidality screening tool in Chinese people with epilepsy. Epilepsy & Behavior 94, pages 216-221.
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Nicholas Abraham, P. Buvanaswari, Rahul Rathakrishnan, Bach X. Tran, Giang Vu. Thu, Long H. Nguyen, Cyrus S. Ho & Roger C. Ho. (2019) A Meta-Analysis of the Rates of Suicide Ideation, Attempts and Deaths in People with Epilepsy. International Journal of Environmental Research and Public Health 16:8, pages 1451.
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Peter R. Camfield, Danielle Andrade, Carole S. Camfield, Jaime Carrizosa-Moog, Richard Appleton, Michel Baulac, Lawrence Brown, Eleonor Ben Menachem, Helen Cross, Isabelle Desguerre, Christina Grant, Hassan Hosny, Laura Jurasek, Marco Mula, Margarete Pfäfflin, Sylvain Rheims, Howard Ring, Renée A. Shellhaas, K.P. Vinayan, Elaine Wirrell & Rima Nabbout. (2019) How can transition to adult care be best orchestrated for adolescents with epilepsy?. Epilepsy & Behavior 93, pages 138-147.
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Takuji Nishida, Sang Kun Lee, Tony Wu, Somsak Tiamkao & Amitabh Dash. (2019) Efficacy and safety of perampanel in generalized and focal to bilateral tonic-clonic seizures: A comparative study of Asian and non-Asian populations. Epilepsia 60, pages 47-59.
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Qian Li, Deng Chen, Li-na Zhu, Hai-jiao Wang, Da Xu, Ge Tan, Yu Zhang & Ling Liu. (2019) Depression in people with epilepsy in West China: Status, risk factors and treatment gap. Seizure 66, pages 86-92.
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C. Vallée, A. Biraben, A. Nica & M. Loiseau. (2019) Épidémiologie et facteurs associés au syndrome dépressif chez les patients suivis au centre hospitalo-universitaire de Rennes pour une épilepsie. L'Encéphale 45:1, pages 40-45.
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M. S. Zinchuk, A. S. Avedisova, E. V. Pashnin, N. I. Voinova & A. B. Guekht. (2019) Suicidological research in epilepsy: problems of methodology. Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova 119:11, pages 23.
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Amal Nishantha Vadysinghe & Solokara Mudiyanselage Nirmani Kaus Thilakarathne. (2018) Overdose of carbamazepine before hanging by a child: a case report of a complex suicide. Egyptian Journal of Forensic Sciences 8:1.
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Dylan P. Thibault, Adys Mendizabal, Nicholas S. Abend, Kathryn A. Davis, James Crispo & Allison W. Willis. (2016) Hospital care for mental health and substance abuse in children with epilepsy. Epilepsy & Behavior 57, pages 161-166.
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Shaun E. Gruenbaum, Helen Wang, Hitten P. Zaveri, Amber B. Tang, Tih-Shih W. Lee, Tore Eid & Roni Dhaher. (2015) Inhibition of glutamine synthetase in the central nucleus of the amygdala induces anhedonic behavior and recurrent seizures in a rat model of mesial temporal lobe epilepsy. Epilepsy & Behavior 51, pages 96-103.
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Jong-Geun SeoJang-Joon LeeYong Won ChoSe-Jin LeeJi-Eun KimHye-Jin MoonSung-Pa Park. (2015) Suicidality and Its Risk Factors in Korean People with Epilepsy: A MEPSY Study. Journal of Clinical Neurology 11:1, pages 32.
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Anand D. Gandhi. (2014) Symptomatic and drug factors contributing to undiagnosed depression in epilepsy. Neurology, Psychiatry and Brain Research 20:4, pages 87-92.
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Gujjar Amruth, Praveen-kumar Srikanteswara, Boraiah Nataraju & Pandiyan Kasturi. (2018) Study of quality of life in epilepsy patients with psychiatric co-morbidities using QOLIE-31. International Journal of Epilepsy 01:01, pages 008-015.
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Cristina Maria Duarte Wigg, Alberto Filgueiras & Marleide da Mota Gomes. (2014) The relationship between sleep quality, depression, and anxiety in patients with epilepsy and suicidal ideation. Arquivos de Neuro-Psiquiatria 72:5, pages 344-348.
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G. Amruth, S. Praveen-kumar, B. Nataraju & P. Kasturi. (2014) Study of psychiatric comorbidities in epilepsy by using the Mini International Neuropsychiatric Interview. Epilepsy & Behavior 33, pages 94-100.
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Milena Gandy, Louise Sharpe, Kathryn Nicholson Perry, Laurie Miller, Zoe Thayer, Janet Boserio & Armin Mohamed. (2013) The psychosocial correlates of depressive disorders and suicide risk in people with epilepsy. Journal of Psychosomatic Research 74:3, pages 227-232.
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Jay Salpekar, Matthew Byrne & Georgann Ferrone. 2012. Epilepsy in Children and Adolescents. Epilepsy in Children and Adolescents 1 16 .
Christian Hoppe & Christian E. Elger. (2011) Depression in epilepsy: a critical review from a clinical perspective. Nature Reviews Neurology 7:8, pages 462-472.
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Emilio Russo, Rita Citraro, Francesca Scicchitano, Salvatore De Fazio, Ida Perrota, Eugenio D. Di Paola, Andrew Constanti & Giovambattista De Sarro. (2011) Effects of early long-term treatment with antiepileptic drugs on development of seizures and depressive-like behavior in a rat genetic absence epilepsy model. Epilepsia 52:7, pages 1341-1350.
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Dale C. Hesdorffer, Anne T. Berg & Andres M. Kanner. (2010) An Update on Antiepileptic Drugs and Suicide: Are There Definitive Answers Yet?. Epilepsy Currents 10:6, pages 137-145.
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Hye-Won LimHyun-Seok SongYang-Ha HwangHo-Won LeeChung-Kyu SuhSung-Pa ParkSoon-Hak Kwon. (2010) Predictors of Suicidal Ideation in People with Epilepsy Living in Korea. Journal of Clinical Neurology 6:2, pages 81.
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Fulvio A. Scorza, Vera C. Terra, Ricardo M. Arida, Marly de Albuquerque & Esper A. Cavalheiro. (2009) How low can we go? A possible relationship between low plasma cholesterol levels and suicide in people with epilepsy. Epilepsy & Behavior 16:2, pages 368.
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Gail S Bell & Josemir W Sander. (2009) Suicide and epilepsy. Current Opinion in Neurology 22:2, pages 174-178.
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Cynthia L. Harden, Luydmilla Jovine, Fadime T. Burgut, Bridget T. Carey, Blagovest G. Nikolov & Stephen J. Ferrando. (2009) A comparison of personality disorder characteristics of patients with nonepileptic psychogenic pseudoseizures with those of patients with epilepsy. Epilepsy & Behavior 14:3, pages 481-483.
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