Citations (75)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (9)
Nafaa Alzobaidi, Huma Quasimi, Nasr A Emad, Abdulsalam Alhalmi & Maaz Naqvi. (2021) Bioactive Compounds and Traditional Herbal Medicine: Promising Approaches for the Treatment of Dementia. Degenerative Neurological and Neuromuscular Disease 11, pages 1-14.
Read now
Read now
Panek Małgorzata, Kawalec Paweł, Malinowska Lipień Iwona, Tomasz Brzostek & Pilc Andrzej. (2020) Glutamatergic dysregulation in mood disorders: opportunities for the discovery of novel drug targets. Expert Opinion on Therapeutic Targets 24:12, pages 1187-1209.
Read now
Read now
Ehtesham Shamsher, Benjamin M. Davis, Timothy E. Yap, Li Guo & Maria Francesca Cordeiro. (2019) Neuroprotection in glaucoma: old concepts, new ideas. Expert Review of Ophthalmology 14:2, pages 101-113.
Read now
Read now
Ramakrishna V. S. Nirogi, Thrinath Reddy Bandyala, Pamuletinarasimha Reddy Gangadasari & Mukkanti Khagga. (2016) Synthesis and biological evaluation of novel N1-phenylsulphonyl indole derivatives as potent and selective 5-HT6R ligands for the treatment of cognitive disorders. Journal of Enzyme Inhibition and Medicinal Chemistry 31:sup1, pages 1-15.
Read now
Read now
Walter J Lukiw. (2012) Amyloid beta (Aβ) peptide modulators and other current treatment strategies for Alzheimer’s disease (AD). Expert Opinion on Emerging Drugs 17:1, pages 43-60.
Read now
Read now
Indrapal Singh & George T Grossberg. (2011) Critical appraisal and role of memantine extended-release in the management of Alzheimer’s disease. Degenerative Neurological and Neuromuscular Disease 1, pages 9-13.
Read now
Read now
Geoffrey A Kerchner, Maria Carmela Tartaglia & Adam L Boxer. (2011) Abhorring the vacuum: use of Alzheimer’s disease medications in frontotemporal dementia. Expert Review of Neurotherapeutics 11:5, pages 709-717.
Read now
Read now
Geoffrey A Kerchner & Adam L Boxer. (2010) Bapineuzumab. Expert Opinion on Biological Therapy 10:7, pages 1121-1130.
Read now
Read now
Nazem Bassil, Papan Thaipisuttikul & George T Grossberg. (2010) Memantine ER, a once-daily formulation for the treatment of Alzheimer's disease. Expert Opinion on Pharmacotherapy 11:10, pages 1765-1771.
Read now
Read now
Articles from other publishers (66)
Ignazia Mocci, Maria Antonietta Casu, Valeria Sogos, Anna Liscia, Rossella Angius, Francesca Cadeddu, Maura Fanti, Patrizia Muroni, Giuseppe Talani, Andrea Diana, Maria Collu & Maria Dolores Setzu. (2023)
Effects of memantine on mania‐like phenotypes exhibited by
Drosophila Shaker
mutants
. CNS Neuroscience & Therapeutics 29:7, pages 1750-1761.
Crossref
Crossref
M. Margarida Martins, Paula S. Branco & Luísa M. Ferreira. (2023) Enhancing the Therapeutic Effect in Alzheimer's Disease Drugs: The role of Polypharmacology and Cholinesterase inhibitors. ChemistrySelect 8:10.
Crossref
Crossref
Débora Nunes, Joana A. Loureiro & Maria Carmo Pereira. (2022) Drug Delivery Systems as a Strategy to Improve the Efficacy of FDA-Approved Alzheimer’s Drugs. Pharmaceutics 14:11, pages 2296.
Crossref
Crossref
Rouchan Ali, Ghanshyam Das Gupta & Pooja A. Chawla. (2022) Aducanumab: A new hope in Alzheimer's disease. Health Sciences Review 4, pages 100039.
Crossref
Crossref
Emily Sun, Aishat Motolani, Leonardo Campos & Tao Lu. (2022) The Pivotal Role of NF-kB in the Pathogenesis and Therapeutics of Alzheimer’s Disease. International Journal of Molecular Sciences 23:16, pages 8972.
Crossref
Crossref
Pravat K. Mandal, Rimil Guha Roy & Avantika Samkaria. (2022) Oxidative Stress: Glutathione and Its Potential to Protect Methionine-35 of Aβ Peptide from Oxidation. ACS Omega 7:31, pages 27052-27061.
Crossref
Crossref
Iva Markulin, Marija Matasin, Viktorija Erdeljic Turk & Melita Salković-Petrisic. (2022) Challenges of repurposing tetracyclines for the treatment of Alzheimer’s and Parkinson’s disease. Journal of Neural Transmission 129:5-6, pages 773-804.
Crossref
Crossref
María C. Ovejero-Benito, Dolores Ochoa, Teresa Enrique-Benedito, Miriam del Peso-Casado, Pablo Zubiaur, Marcos Navares, Manuel Román & Francisco Abad-Santos. (2022) Pharmacogenetics of Donepezil and Memantine in Healthy Subjects. Journal of Personalized Medicine 12:5, pages 788.
Crossref
Crossref
Manish Kumar & Nitin Bansal. (2022) A Revisit to Etiopathogenesis and Therapeutic Strategies in Alzheimer’s
Disease. Current Drug Targets 23:5, pages 486-512.
Crossref
Crossref
Changyong Guo, Di Wen, Yihong Zhang, Richie Mustaklem, Basil Mustaklem, Miou Zhou, Tao Ma & Yao-Ying Ma. (2022) Amyloid-β oligomers in the nucleus accumbens decrease motivation via insertion of calcium-permeable AMPA receptors. Molecular Psychiatry 27:4, pages 2146-2157.
Crossref
Crossref
Anton N. Shuvaev, Olga S. Belozor, Oleg I. Mozhei, Elena D. Khilazheva, Andrey N. Shuvaev, Yana V. Fritsler & S. Kasparov. (2021) Protective Effect of Memantine on Bergmann Glia and Purkinje Cells Morphology in Optogenetic Model of Neurodegeneration in Mice. International Journal of Molecular Sciences 22:15, pages 7822.
Crossref
Crossref
Yuan-Ri Guo, Hui JinMinsang KimMyeong Bae ShinJu Hyeong LeeSungho MaengSeung-Yun ChaJeonghun LeeYoung Ho KohKee-Young KimSangkuk KangHyunwoo ParkJoo Won Suh. (2021)
Synergistic Neuroprotective Effects of Mature Silkworm and
Angelica gigas
Against Scopolamine-Induced Mild Cognitive Impairment in Mice and H
2
O
2
-Induced Cell Death in HT22 Mouse Hippocampal Neuronal Cells
. Journal of Medicinal Food 24:5, pages 505-516.
Crossref
Crossref
Jinsha Liu, Joey Paolo Ting, Shams Al-Azzam, Yun Ding & Sepideh Afshar. (2021) Therapeutic Advances in Diabetes, Autoimmune, and Neurological Diseases. International Journal of Molecular Sciences 22:6, pages 2805.
Crossref
Crossref
Christian Wilson R. Turalde, Adrian I. Espiritu & Veeda Michelle M. Anlacan. (2021) Memantine for Multiple Sclerosis: A Systematic Review and Meta-Analysis of Randomized Trials. Frontiers in Neurology 11.
Crossref
Crossref
Lauren V. Owens, Alexandre Benedetto, Neil Dawson, Christopher J. Gaffney & Edward T. Parkin. (2021) Gene therapy-mediated enhancement of protective protein expression for the treatment of Alzheimer’s disease. Brain Research 1753, pages 147264.
Crossref
Crossref
Gerhard Multhaup & Filip Liebsch. 2021. Encyclopedia of Molecular Pharmacology. Encyclopedia of Molecular Pharmacology
84
89
.
Roma Ghai, Kandasamy Nagarajan, Meenakshi Arora, Parul Grover, Nazakat Ali & Garima Kapoor. (2020) Current Strategies and Novel Drug Approaches for Alzheimer Disease. CNS & Neurological Disorders - Drug Targets 19:9, pages 676-690.
Crossref
Crossref
G. Siano, M. Varisco, A. Scarlatti, M.C. Caiazza, K. Dunville, F. Cremisi, M. Costa, L. Pancrazi, C. Di Primio & A. Cattaneo. (2020) Gene Expression of Disease-related Genes in Alzheimer’s Disease is Impaired by Tau Aggregation. Journal of Molecular Biology 432:24, pages 166675.
Crossref
Crossref
Patrizia Polverino de Laureto, Luana Palazzi & Laura Acquasaliente. 2020. Neuroprotection - New Approaches and Prospects. Neuroprotection - New Approaches and Prospects.
V.A. Gorbachenko & E.A. Lukyanetz. (2020) Effects of memantine on the passive avoidance test in young rats. Fiziolohichnyĭ zhurnal 66:5, pages 3-10.
Crossref
Crossref
Madeeha Nasir, Daniel Trujillo, Jessica Levine, Jennifer B. Dwyer, Zachary W. Rupp & Michael H. Bloch. (2020) Glutamate Systems in DSM-5 Anxiety Disorders: Their Role and a Review of Glutamate and GABA Psychopharmacology. Frontiers in Psychiatry 11.
Crossref
Crossref
Vidyasagar Naik Bukke, Moola Archana, Rosanna Villani, Antonino Davide Romano, Agata Wawrzyniak, Krzysztof Balawender, Stanislaw Orkisz, Sarah Beggiato, Gaetano Serviddio & Tommaso Cassano. (2020) The Dual Role of Glutamatergic Neurotransmission in Alzheimer’s Disease: From Pathophysiology to Pharmacotherapy. International Journal of Molecular Sciences 21:20, pages 7452.
Crossref
Crossref
Yan Sun, Sameer C. Dhamne, Alejandro Carretero‐Guillén, Ricardo Salvador, Marti C. Goldenberg, Brianna R. Godlewski, Alvaro Pascual‐Leone, Joseph R. Madsen, Scellig S. D. Stone, Giulio Ruffini, Javier Márquez‐Ruiz & Alexander Rotenberg. (2020) Drug‐Responsive Inhomogeneous Cortical Modulation by Direct Current Stimulation. Annals of Neurology 88:3, pages 489-502.
Crossref
Crossref
Shashikala Bhute, Deepaneeta Sarmah, Aishika Datta, Pallavi Rane, Amit Shard, Avirag Goswami, Anupom Borah, Kiran Kalia, Kunjan R. Dave & Pallab Bhattacharya. (2020) Molecular Pathogenesis and Interventional Strategies for Alzheimer’s Disease: Promises and Pitfalls. ACS Pharmacology & Translational Science 3:3, pages 472-488.
Crossref
Crossref
Chitra Vinnakota, Karan Govindpani, Warren Perry Tate, Katie Peppercorn, Praju Vikas Anekal, Henry John Waldvogel, Richard Lewis Maxwell Faull & Andrea Kwakowsky. (2020) An α5 GABAA Receptor Inverse Agonist, α5IA, Attenuates Amyloid Beta-Induced Neuronal Death in Mouse Hippocampal Cultures. International Journal of Molecular Sciences 21:9, pages 3284.
Crossref
Crossref
Anna Pannaccione, Ilaria Piccialli, Agnese Secondo, Roselia Ciccone, Pasquale Molinaro, Francesca Boscia & Lucio Annunziato. (2020) The Na+/Ca2+exchanger in Alzheimer’s disease. Cell Calcium 87, pages 102190.
Crossref
Crossref
Kelly Ceyzériat, Thomas Zilli, Philippe Millet, Giovanni B. Frisoni, Valentina Garibotto & Benjamin B. Tournier. (2020) Learning from the Past: A Review of Clinical Trials Targeting Amyloid, Tau and Neuroinflammation in Alzheimer’s Disease. Current Alzheimer Research 17:2, pages 112-125.
Crossref
Crossref
Yutaka Nakagawa & Shizuo Yamada. (2020) Metal homeostasis disturbances in neurodegenerative disorders, with special emphasis on Creutzfeldt-Jakob disease – Potential pathogenetic mechanism and therapeutic implications. Pharmacology & Therapeutics 207, pages 107455.
Crossref
Crossref
Gerhard Multhaup & Filip Liebsch. 2020. Encyclopedia of Molecular Pharmacology. Encyclopedia of Molecular Pharmacology
1
6
.
Anna Karla dos Santos Pereira, Douglas Hideki Nakahata, Carlos Marrote Manzano, Déborah de Alencar Simoni, Douglas Henrique Pereira, Wilton Rogério Lustri, André Luiz Barboza Formiga & Pedro Paulo Corbi. (2019) Synthesis, crystallographic studies, molecular modeling and in vitro biological studies of silver(I) complexes with aminoadamantane ligands. Polyhedron 173, pages 114116.
Crossref
Crossref
Eunkuk Park, Min Jeong Ryu, Nam Ki Kim, Mun Hyoung Bae, Youngha Seo, Jeonghyun Kim, Subin Yeo, Memoona Kanwal, Chun Whan Choi, Jun Young Heo & Seon-Yong Jeong. (2019) Synergistic Neuroprotective Effect of Schisandra chinensis and Ribes fasciculatum on Neuronal Cell Death and Scopolamine-Induced Cognitive Impairment in Rats. International Journal of Molecular Sciences 20:18, pages 4517.
Crossref
Crossref
Azime Berna Özçelik, Mevlüt Akdağ, Muhammed Ergün & Mehtap UYSAL. (2019) Alzheimer Hastalığının Tedavisinde Kullanılan İlaçlar ve Yeni YaklaşımlarDrug Used in the Treatment of Alzheimer’s Disease and New Approaches. Erzincan Üniversitesi Fen Bilimleri Enstitüsü Dergisi 12:2, pages 1149-1159.
Crossref
Crossref
Pallavi Duggal & Sidharth Mehan. (2019) Neuroprotective Approach of Anti-Cancer Microtubule Stabilizers Against Tauopathy Associated Dementia: Current Status of Clinical and Preclinical Findings. Journal of Alzheimer's Disease Reports 3:1, pages 179-218.
Crossref
Crossref
Wesley Peng, Georgia Minakaki, Maria Nguyen & Dimitri Krainc. (2019) Preserving Lysosomal Function in the Aging Brain: Insights from Neurodegeneration. Neurotherapeutics 16:3, pages 611-634.
Crossref
Crossref
Ying-Jui Ho, Mei-Shiuan Shen, Chun-Hwei Tai, Hsin-Hua Li, Jian-Horng Chen, Wen-Chieh Liao, Pai-Yi Chiu, I-Yen Lee, Chih-Li Lin & Ching-Sui Hung. (2019) Use of Ceftriaxone in Treating Cognitive and Neuronal Deficits Associated With Dementia With Lewy Bodies. Frontiers in Neuroscience 13.
Crossref
Crossref
Ahmad Almahozi, Mohamed Radhi, Suja Alzayer & Amer Kamal. (2019) Effects of Memantine in a Mouse Model of Postoperative Cognitive Dysfunction. Behavioral Sciences 9:3, pages 24.
Crossref
Crossref
Jiahong Sun, Jan Michelle Martin, Victoria Vanderpoel & Rachita K. Sumbria. (2019) The Promises and Challenges of Erythropoietin for Treatment of Alzheimer’s Disease. NeuroMolecular Medicine 21:1, pages 12-24.
Crossref
Crossref
Patrick A. Lewis & Jennifer E. Spillane. 2019. The Molecular and Clinical Pathology of Neurodegenerative Disease. The Molecular and Clinical Pathology of Neurodegenerative Disease
25
82
.
Shiwei Song, Abul Fajol, Yan Chen, Baogang Ren & Songsheng Shi. (2018) Anticonvulsive effects of protodioscin against pilocarpine-induced epilepsy. European Journal of Pharmacology 833, pages 237-246.
Crossref
Crossref
Chanshuai Han, Mathilde Chaineau, Carol X.-Q. Chen, Lenore K. Beitel & Thomas M. Durcan. (2018) Open Science Meets Stem Cells: A New Drug Discovery Approach for Neurodegenerative Disorders. Frontiers in Neuroscience 12.
Crossref
Crossref
Giulia Romano, Nikola Holodkov, Raffaella Klima, Federica Grilli, Corrado Guarnaccia, Monica Nizzardo, Federica Rizzo, Rodolfo Garcia & Fabian Feiguin. (2018) Downregulation of glutamic acid decarboxylase in Drosophila TDP-43-null brains provokes paralysis by affecting the organization of the neuromuscular synapses. Scientific Reports 8:1.
Crossref
Crossref
Shweta Dang, Deeksha Mehtani, Atinderpal Kaur & Reema Gabrani. 2018. Functional Food and Human Health. Functional Food and Human Health
227
245
.
S. del Río-Sancho, C.E. Serna-Jiménez, M. Sebastián-Morelló, M.A. Calatayud-Pascual, C. Balaguer-Fernández, A. Femenía-Font, Y.N. Kalia, V. Merino & A. López-Castellano. (2017) Transdermal therapeutic systems for memantine delivery. Comparison of passive and iontophoretic transport. International Journal of Pharmaceutics 517:1-2, pages 104-111.
Crossref
Crossref
Naoyuki Kitagawa & Michio Sakurai. (2016) Memantine‐induced sustained unconsciousness. Neurology and Clinical Neuroscience 4:6, pages 236-238.
Crossref
Crossref
Latha Devi & Masuo Ohno. (2016) Cognitive benefits of memantine in Alzheimer's 5XFAD model mice decline during advanced disease stages. Pharmacology Biochemistry and Behavior 144, pages 60-66.
Crossref
Crossref
Mauricio P. Cunha, Vicente Lieberknecht, Ana Belén Ramos-Hryb, Gislaine Olescowicz, Fabiana K. Ludka, Carla I. Tasca, Nelson H. Gabilan & Ana Lúcia S. Rodrigues. (2016) Creatine affords protection against glutamate-induced nitrosative and oxidative stress. Neurochemistry International 95, pages 4-14.
Crossref
Crossref
Pei Li, Wayne D. Beck, Patrick M. Callahan, Alvin V. TerryJr.Jr. & Michael G. Bartlett. (2015) Pharmacokinetics of cotinine in rats: A potential therapeutic agent for disorders of cognitive function. Pharmacological Reports 67:3, pages 494-500.
Crossref
Crossref
Shuichi Yanai & Shogo Endo. 2015. Aging Mechanisms. Aging Mechanisms
257
274
.
Zengjun Fang, Yu’ning Song, Peng Zhan, Qingzhu Zhang & Xinyong Liu. (2014) Conformational restriction: an effective tactic in 'follow-on'-based drug discovery. Future Medicinal Chemistry 6:8, pages 885-901.
Crossref
Crossref
Qiongman Kong, Ling-Chu Chang, Kou Takahashi, Qibing Liu, Delanie A. Schulte, Liching Lai, Brian Ibabao, Yuchen Lin, Nathan Stouffer, Chitra Das Mukhopadhyay, Xuechao Xing, Kathleen I. Seyb, Gregory D. Cuny, Marcie A. Glicksman & Chien-Liang Glenn Lin. (2014) Small-molecule activator of glutamate transporter EAAT2 translation provides neuroprotection. Journal of Clinical Investigation 124:3, pages 1255-1267.
Crossref
Crossref
Ina Tesseur, Anna A. Pimenova, Adrian C. Lo, Marta Ciesielska, Stefan F. Lichtenthaler, Joris H. De Maeyer, Jan A.J. Schuurkes, Rudi D'Hooge & Bart De Strooper. (2013) Chronic 5-HT4 receptor activation decreases Aβ production and deposition in hAPP/PS1 mice. Neurobiology of Aging 34:7, pages 1779-1789.
Crossref
Crossref
Gary Mitchell. (2013) Applying pharmacology to practice: The case of dementia. Nurse Prescribing 11:4, pages 185-190.
Crossref
Crossref
Jay S. Schneider, Elsa Y. Pioli, Yang Jianzhong, Qin Li & Erwan Bezard. (2013) Effects of memantine and galantamine on cognitive performance in aged rhesus macaques. Neurobiology of Aging 34:4, pages 1126-1132.
Crossref
Crossref
Chaoyun Li, Azadeh Ebrahimi & Hermann Schluesener. (2013) Drug pipeline in neurodegeneration based on transgenic mice models of Alzheimer's disease. Ageing Research Reviews 12:1, pages 116-140.
Crossref
Crossref
Chien-Liang Glenn LinQiongman Kong, Gregory D Cuny & Marcie A Glicksman. (2012) Glutamate transporter EAAT2: a new target for the treatment of neurodegenerative diseases. Future Medicinal Chemistry 4:13, pages 1689-1700.
Crossref
Crossref
S. del Rio-Sancho, C.E. Serna-Jiménez, M.A. Calatayud-Pascual, C. Balaguer-Fernández, A. Femenía-Font, V. Merino & A. López-Castellano. (2012) Transdermal absorption of memantine – Effect of chemical enhancers, iontophoresis, and role of enhancer lipophilicity. European Journal of Pharmaceutics and Biopharmaceutics 82:1, pages 164-170.
Crossref
Crossref
Seishi Terada & Yosuke Uchitomi. (2012) WITHDRAWN: Auditory hallucination and agitation due to memantine in a patient with Alzheimer's disease: a case report. General Hospital Psychiatry.
Crossref
Crossref
Li-Ling Cheng, Xi-Nan Chen, Yu Wang, Lu Yu, Xi Kuang, Lu-Lu Wang, Wen Yang & Jun-Rong Du. (2011) Z-ligustilide isolated from Radix Angelicae sinensis ameliorates the memory impairment induced by scopolamine in mice. Fitoterapia 82:7, pages 1128-1132.
Crossref
Crossref
Alvin V. TerryJr.Jr., Patrick M. Callahan, Brandon Hall & Scott J. Webster. (2011) Alzheimer's disease and age-related memory decline (preclinical). Pharmacology Biochemistry and Behavior 99:2, pages 190-210.
Crossref
Crossref
Fei Shen, Jacqueline A.M. Smith, Ray Chang, David L. Bourdet, Pamela R. Tsuruda, Glenmar P. Obedencio & David T. Beattie. (2011) 5-HT4 receptor agonist mediated enhancement of cognitive function in vivo and amyloid precursor protein processing in vitro: A pharmacodynamic and pharmacokinetic assessment. Neuropharmacology 61:1-2, pages 69-79.
Crossref
Crossref
Rüdiger Hardeland. (2011) Cognitive Enhancers in Moderate to Severe Alzheimer's Disease. Clinical Medicine Insights: Therapeutics 3, pages CMT.S6344.
Crossref
Crossref
Alessandro Martorana, Zaira Esposito & Giacomo Koch. (2010) Beyond the Cholinergic Hypothesis: Do Current Drugs Work in Alzheimer's Disease?. CNS Neuroscience & Therapeutics, pages no-no.
Crossref
Crossref
C. Levasseur. (2010) Mémantine (Ebixa®). NPG Neurologie - Psychiatrie - Gériatrie 10:57, pages 136-140.
Crossref
Crossref
Adam C. Strauss & Jordan D. Dimitrakov. (2010) New treatments for chronic prostatitis/chronic pelvic pain syndrome. Nature Reviews Urology 7:3, pages 127-135.
Crossref
Crossref
Massimo Tabaton, George Perry, Xiongwei Zhu, Hyoung-gon Lee, Gemma Casadesus & Mark A. Smith. (2010) Memantine. The American Journal of Pathology 176:2, pages 540-541.
Crossref
Crossref
Tzong-Yuan Wu & Chih-Ping Chen. (2009) Dual Action of Memantine in Alzheimer Disease: A Hypothesis. Taiwanese Journal of Obstetrics and Gynecology 48:3, pages 273-277.
Crossref
Crossref