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Original Research

A new agent for the treatment of noninfectious uveitis: rationale and design of three LUMINATE (Lux Uveitis Multicenter Investigation of a New Approach to Treatment) trials of steroid-sparing voclosporin

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Pages 693-702 | Published online: 05 Dec 2008

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Read on this site (8)

Yan Li, Maria Palmisano, Duxin Sun & Simon Zhou. (2020) Pharmacokinetic Disposition Difference Between Cyclosporine and Voclosporin Drives Their Distinct Efficacy and Safety Profiles in Clinical Studies. Clinical Pharmacology: Advances and Applications 12, pages 83-96.
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Hui Yi Tan, Aniruddha Agarwal, Cecilia S Lee, Jay Chhablani, Vishali Gupta, Manoj Khatri, Jayabalan Nirmal, Carlos Pavesio & Rupesh Agrawal. (2016) Management of noninfectious posterior uveitis with intravitreal drug therapy. Clinical Ophthalmology 10, pages 1983-2020.
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Osama Gheith, Torki Al-Otaibi & Hany Mansour. (2014) Next-generation calcineurin inhibitors in development for the prevention of organ rejection. Transplant Research and Risk Management 6, pages 23-30.
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Robert J Barry, Quan Dong Nguyen, Richard W Lee, Philip I Murray & Alastair K Denniston. (2014) Pharmacotherapy for uveitis: current management and emerging therapy. Clinical Ophthalmology 8, pages 1891-1911.
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Martin Roesel, Christoph Tappeiner, Arnd Heiligenhaus & Carsten Heinz. (2011) Oral voclosporin: novel calcineurin inhibitor for treatment of noninfectious uveitis. Clinical Ophthalmology 5, pages 1309-1313.
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Sana S Siddique, Rajiv Shah, Ana M Suelves & Charles Stephen Foster. (2011) Road to remission: a comprehensive review of therapy in uveitis. Expert Opinion on Investigational Drugs 20:11, pages 1497-1515.
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Yasir Jamal Sepah, Elizabeth Harlan Michelle, Brandon Metcalf, Afsheen Khwaja, Roomasa Channa, Mohamed Ibrahim, Elham Hatef, Jangwon Heo, Jeong Lee Hee, Zubir Samsuddin Rentiya, Diana V Do & Quan Dong Nguyen. (2011) Voclosporin: a potentially promising therapeutic agent for noninfectious uveitis. Expert Review of Ophthalmology 6:3, pages 281-286.
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Frank F Lee & Charles Stephen Foster. (2010) Pharmacotherapy of uveitis. Expert Opinion on Pharmacotherapy 11:7, pages 1135-1146.
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Articles from other publishers (8)

Emaad Abdel-Kahaar & Frieder Keller. (2023) Clinical Pharmacokinetics and Pharmacodynamics of Voclosporin. Clinical Pharmacokinetics 62:5, pages 693-703.
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Douglas A Jabs, Meghan K Berkenstock, Michael M Altaweel, Janet T Holbrook & Elizabeth A Sugar. (2022) The Conundrum of Clinical Trials for the Uveitides: Appropriate Outcome Measures for One Treatment Used in Several Diseases. Epidemiologic Reviews 44:1, pages 2-16.
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Huiya Zhang & Shiyu Chen. (2022) Cyclic peptide drugs approved in the last two decades (2001–2021). RSC Chemical Biology 3:1, pages 18-31.
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Jane S. Kim, Jared E. Knickelbein, Robert B. Nussenblatt & H. Nida Sen. (2015) Clinical Trials in Noninfectious Uveitis. International Ophthalmology Clinics 55:3, pages 79-110.
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Claudia Castiblanco & C. Stephen Foster. (2014) Review of Systemic Immunosuppression for Autoimmune Uveitis. Ophthalmology and Therapy 3:1-2, pages 17-36.
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Jamie Lynne Metzinger & C Stephen Foster. (2013) Emerging therapies for the treatment of uveitis: clinical trial observations. Clinical Investigation 3:10, pages 951-966.
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R W J Lee & A D Dick. (2011) Current concepts and future directions in the pathogenesis and treatment of non-infectious intraocular inflammation. Eye 26:1, pages 17-28.
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Marc D. de Smet, Simon R.J. Taylor, Bahram Bodaghi, Elisabetta Miserocchi, Philip I. Murray, Uwe Pleyer, Manfred Zierhut, Talin Barisani-Asenbauer, Phuc LeHoang & Sue Lightman. (2011) Understanding uveitis: The impact of research on visual outcomes. Progress in Retinal and Eye Research 30:6, pages 452-470.
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