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OncoTargets and Therapy Volume 1, 2008 - Issue
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Review

Polyclonal B-cell lymphocytosis with binucleated lymphocytes (PPBL)

Xavier Troussard1 Laboratoire d’Hématologie Côte de Nacre, Université Caen Basse Normandie Caen, Registre Régional des Hémopathies Malignes de Basse Normandie, FranceCorrespondence[email protected]
,
Edouard Cornet1 Laboratoire d’Hématologie Côte de Nacre, Université Caen Basse Normandie Caen, Registre Régional des Hémopathies Malignes de Basse Normandie, France
,
Jean-François Lesesve2 Laboratoire d’Hématologie, Vandoeuvre-Les-Nancy Cedex, France
,
Carine Kourel3 Département de Génétique Humaine, Laboratoire pasteur-Cerba, Cergy-Pontoise, France For the Groupe Français d’Hématologie cellulaire (GFHC)
&
Hossein Mossafa3 Département de Génétique Humaine, Laboratoire pasteur-Cerba, Cergy-Pontoise, France For the Groupe Français d’Hématologie cellulaire (GFHC)
Pages 59-66 | Published online: 15 Oct 2008

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Jean-François Lesesve, Anne-Lise Gressot, Xavier Troussard, Hossein Mossafa & Edouard Cornet. (2014) Morphologic features of binucleated lymphocytes to assess the diagnosis of persistent B-cell polyclonal lymphocytosis or other mature B-cell neoplasms. Leukemia & Lymphoma 55:7, pages 1551-1556.
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Articles from other publishers (22)

Umberto Maccio & Anton V Rets. (2022) Lymphoid aggregates in bone marrow: a diagnostic pitfall. Journal of Clinical Pathology 75:12, pages 807-814.
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Romain Morizot, Jean-Dominique de Korwin, Pierre Feugier, Julien Broséus, Xavier Troussard & Jean-François Lesesve. (2021) Patients with Persistent Polyclonal B-Cell Lymphocytosis Share the Symptomatic Criteria of Systemic Exertion Intolerance Disease. Journal of Clinical Medicine 10:15, pages 3374.
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Jean-François Lesesve & Xavier Troussard. (2021) Des lymphocytes dystrophiques. Revue Francophone des Laboratoires 2021:532, pages 69-74.
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Laura Bigorra, Iciar Larriba & Ricardo Gutiérrez-Gallego. (2020) Abnormal characteristic “round bottom flask” shape volume-based scattergram as a trigger to suspect persistent polyclonal B-cell lymphocytosis. Clinica Chimica Acta 511, pages 181-188.
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Emily D. Rout, A Russell Moore, Robert C. Burnett, Julia D. Labadie, Kelly L. Hughes, Paul A. Navin, Janna A. Yoshimoto, Paul R. Avery & Anne C. Avery. (2020) Polyclonal B‐cell lymphocytosis in English bulldogs. Journal of Veterinary Internal Medicine 34:6, pages 2622-2635.
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Gayatri Behera, Gaurav Chhabra, Mukund N. Sable, Ashutosh Panigrahi & Dhanlaxmi Shetty. (2020) Multinucleated lymphocytes in chronic lymphocytic leukemia—A rare morphological finding with review. International Journal of Laboratory Hematology 42:4.
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Marzieh Tavakol, Mahnaz Jamee, Gholamreza Azizi, Homa Sadri, Yasser Bagheri, Majid Zaki-Dizaji, Fatemeh Sadat Mahdavi, Farhad Jadidi-Niaragh, Sanaz Tajfirooz, Ali N. Kamali, Fatemeh Aghamahdi, Shahab Noorian, Habibeh Taghavi Kojidi, Mehdi Mosavian, Rahman Matani, Elahe Dolatshahi, Kumars Porrostami, Nasrin Elahimehr, Marzie Fatemi-Abhari, Laleh Sharifi, Reza Arjmand, Sabahat Haghi, Hamed Zainaldain, Reza Yazdani, Mohammadreza Shaghaghi, Hassan Abolhassani & Asghar Aghamohammadi. (2020) Diagnostic Approach to the Patients with Suspected Primary Immunodeficiency. Endocrine, Metabolic & Immune Disorders - Drug Targets 20:2, pages 157-171.
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Torsten HaferlachTorsten Haferlach. 2020. Hämatologische Erkrankungen. Hämatologische Erkrankungen 33 35 .
Elsa Maitre & Xavier Troussard. (2019) Monoclonal B-cell lymphocytosis. Best Practice & Research Clinical Haematology 32:3, pages 229-238.
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Natália Aydos Marcondes, Laiana Schneider, Bianca Michel Spindler, Flavo Beno Fernandes & Gustavo Adolpho Moreira Faulhaber. (2018) Polyclonal B‐cell lymphocytosis: Report of three cases. Cytometry Part B: Clinical Cytometry 94:6, pages 953-955.
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Robert P. Hasserjian. 2018. Diagnosis of Blood and Bone Marrow Disorders. Diagnosis of Blood and Bone Marrow Disorders 329 381 .
Nadine Voelxen, Claudia Wehr, Sylvia Gutenberger, Baerbel Keller, Miriam Erlacher, Cecilia Dominguez‐Conde, Daniela Bertele, Florian Emmerich, Milena Pantic, Stefanie Jennings, Mirzokhid Rakhmanov, Christian Foerster, Uwe M Martens, Uwe Platzbecker, Hans‐Hartmut Peter, Paul Fisch, Kaan Boztug, Hermann Eibel, Ulrich Salzer & Klaus Warnatz. (2016) B‐cell signaling in persistent polyclonal B lymphocytosis (PPBL). Immunology & Cell Biology 94:9, pages 830-837.
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Eleni Magdalini A. Kyritsi, Xanthi Yiakoumis, Gerasimos A. Pangalis, Charalampos Pontikoglou, Katerina Pyrovolaki, Christina Kalpadakis, Irini Mavroudi, Helen Koutala, Semeli Mastrodemou, Theodoros P. Vassilakopoulos, George Vaiopoulos, Evanthia Diamanti-Kandarakis, Helen A. Papadaki & Maria K. Angelopoulou. (2015) High Frequency of Thyroid Disorders in Patients Presenting With Neutropenia to an Outpatient Hematology Clinic STROBE-Compliant Article. Medicine 94:23, pages e886.
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C. Wehr, L. Houet, M. Pantic, S. Gutenberger, F. Emmerich, R. Marks, P. Fisch & Klaus Warnatz. (2015) Recurrence of persistent polyclonal B lymphocytosis (PPBL) after rituximab treatment. Annals of Hematology 94:6, pages 1075-1076.
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Giovanni Carulli, Eugenio M Ciancia, Paola Sammuri, Cristiana Domenichini, Antonio Azzarà, Virginia Ottaviano, Edoardo Benedetti & Mario Petrini. (2015) Modifications in B-Lymphocyte Number and Phenotype in the Course of Pregnancy in a Woman with Persistent Polyclonal B-Cell Lymphocytosis: A Flow Cytometric Study. Journal of Clinical and Experimental Hematopathology 55:2, pages 77-82.
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. 2014. Morphology of Blood Disorders. Morphology of Blood Disorders 587 680 .
M A Berkowska, C Grosserichter-Wagener, H J Adriaansen, D de Ridder, K P Mirani-Oostdijk, H J Agteresch, S Böttcher, A Orfao, J J M van Dongen & M C van Zelm. (2014) Persistent polyclonal B-cell lymphocytosis: extensively proliferated CD27+IgM+IgD+ memory B cells with a distinctive immunophenotype. Leukemia 28:7, pages 1560-1564.
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Faramarz Naeim, P. Nagesh Rao, Sophie X. Song & Wayne W. Grody. 2013. Atlas of Hematopathology. Atlas of Hematopathology 627 633 .
Charles Chevalier, Bernard Husson & Gautier Detry. (2013) Polyclonal B lymphocytosis with binucleated lymphocytes in a man. American Journal of Hematology 88:1, pages 86-86.
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Dimitra Anagnostou. 2012. Bone Marrow Lymphoid Infiltrates. Bone Marrow Lymphoid Infiltrates 113 144 .
J. F. Lesesve, J. Devignes, J. Sokolowska, I. Aimone-Gastin, C. Jacob, D. Wahl, X. Troussard & T. Lecompte. (2011) IgM interference in determination of antiphospholipid antibodies and erythrocyte sedimentation rate in persistent polyclonal B-cell lymphocytosis with binucleated lymphocytes. International Journal of Laboratory Hematology, pages no-no.
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Faramarz Naeim, P. Nagesh Rao, Sophie X. Song & Ryan T. Phan. 2008. Atlas of Hematopathology. Atlas of Hematopathology 821 828 .

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