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Original Research

One-pill once-a-day HAART: a simplification strategy that improves adherence and quality of life of HIV-infected subjects

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Pages 115-125 | Published online: 04 May 2010

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Hung-Chin Tsai, I-Tzu Chen, Hui-Min Chang, Susan Shin-Jung Lee & Yao-Shen Chen. (2022) Trend of HIV Transmitted Drug Resistance After the Introduction of Single-Tablet Regimens in Southern Taiwan. Infection and Drug Resistance 15, pages 5495-5507.
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Hung-Chin Tsai, I-Tzu Chen, Hui-Min Chang, Susan Shin-Jung Lee & Yao-Shen Chen. (2022) High Prevalence of Doravirine Resistance in HIV-1-Infected Patients with Virological Failure to an NNRTI-Based Single-Tablet Regimen. Infection and Drug Resistance 15, pages 3857-3869.
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Tsegaye Melaku, Girma Mamo, Legese Chelkeba & Tesfahun Chanie. (2020) Health-Related Quality of Life Among People Living with Human Immunodeficiency Virus on Highly Active Antiretroviral Therapy in Ethiopia: PROQOL-HIV Based Survey. Patient Related Outcome Measures 11, pages 73-86.
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Simone Furtado dos Santos, Celline Cardoso Almeida-Brasil, Juliana de Oliveira Costa, Edna Afonso Reis, Márcio Afonso Cruz, Micheline Rosa Silveira & Maria das Graças Braga Ceccato. (2020) Does switching from multiple to single-tablet regimen containing the same antiretroviral drugs improve adherence? A group-based trajectory modeling analysis. AIDS Care 32:10, pages 1268-1276.
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J. Jaiswal, M. D. Francis, S. N. Singer, K. B. Dunlap, A. B. Cox & R. Greene. (2020) “Worn out”: Coping strategies for managing antiretroviral treatment fatigue among urban people of color living with HIV who were recently disengaged from outpatient HIV care. Journal of HIV/AIDS & Social Services 19:2, pages 173-187.
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Hung-Chin Tsai, I-Tzu Chen, Susan Shin-Jung Lee & Yao-Shen Chen. (2018) HIV-1 genotypic drug resistance in patients with virological failure to single-tablet antiretroviral regimens in southern Taiwan. Infection and Drug Resistance 11, pages 1061-1071.
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Kamban Hirasen, Denise Evans, Mhairi Maskew, Ian M Sanne, Kate Shearer, Caroline Govathson, Given Malete, Sheryl A Kluberg & Matthew P Fox. (2018) The right combination – treatment outcomes among HIV-positive patients initiating first-line fixed-dose antiretroviral therapy in a public sector HIV clinic in Johannesburg, South Africa. Clinical Epidemiology 10, pages 17-29.
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Vagish Hemmige, Charlene A. Flash, Josephinel Carter, Thomas P. Giordano & Teddy Zerai. (2018) Single tablet HIV regimens facilitate virologic suppression and retention in care among treatment naïve patients. AIDS Care 30:8, pages 1017-1024.
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Godfrey Mutashambara Rwegerera, Thato Moshomo, Marea Gaenamong, Taibat Aderonke Oyewo, Sivasomnath Gollakota, Yordanka Piña Rivera, Anthony Masaka, Brian Godman, Meshack Shimwela & Dereje Habte. (2018) Health-related quality of life and associated factors among patients with diabetes mellitus in Botswana. Alexandria Journal of Medicine 54:2, pages 111-118.
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Eric M. Maiese, Phaedra T. Johnson, Tim Bancroft, Alyssa Goolsby Hunter & Albert W. Wu. (2016) Quality of life of HIV-infected patients who switch antiretroviral medication due to side effects or other reasons. Current Medical Research and Opinion 32:12, pages 2039-2046.
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Laura Comi & Franco Maggiolo. (2016) Abacavir + dolutegravir + lamivudine for the treatment of HIV. Expert Opinion on Pharmacotherapy 17:15, pages 2097-2106.
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Franco Maggiolo, Giorgio L Colombo, Sergio Di Matteo, Giacomo M Bruno, Noemi Astuti, Elisa Di Filippo, Giulia Masini & Claudia Bernardini. (2015) Cost-effectiveness analysis of antiretroviral therapy in a cohort of HIV-infected patients starting first-line highly active antiretroviral therapy during 6 years of observation. Patient Related Outcome Measures 6, pages 53-60.
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Mario Cruciani & Marina Malena. (2015) Combination dolutegravir–abacavir–lamivudine in the management of HIV/AIDS: clinical utility and patient considerations. Patient Preference and Adherence 9, pages 299-310.
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Misty M Miller, Michelle D Liedtke, Staci M Lockhart & R Chris Rathbun. (2015) The role of dolutegravir in the management of HIV infection. Infection and Drug Resistance 8, pages 19-29.
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Giorgio L Colombo, Antonella Castagna, Sergio Di Matteo, Laura Galli, Giacomo Bruno, Andrea Poli, Stefania Salpietro, Alessia Carbone & Adriano Lazzarin. (2014) Cost analysis of initial highly active antiretroviral therapy regimens for managing human immunodeficiency virus-infected patients according to clinical practice in a hospital setting. Therapeutics and Clinical Risk Management 10, pages 9-15.
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Eva Van den Eynde & Daniel Podzamczer. (2014) Switch strategies in antiretroviral therapy regimens. Expert Review of Anti-infective Therapy 12:9, pages 1055-1074.
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Seth Hill, Jan Kavookjian, Jingjing Qian, Allison Chung & John Vandewaa. (2014) Effects of pill burden on discontinuation of the initial HAART regimen in minority female patients prescribed 1 pill/day versus any other pill burden. AIDS Care 26:5, pages 595-601.
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A. Mills, G. Crofoot, R. Ortiz, B. Rashbaum, W. Towner, D. Ward, C. Brinson, R. Kulkarni, W. Garner, R. Ebrahimi, H. Cao, A. Cheng & J. Szwarcberg. (2014) Switching From Twice-Daily Raltegravir Plus Tenofovir Disoproxil Fumarate/Emtricitabine to Once-Daily Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Disoproxil Fumarate in Virologically Suppressed, HIV-1–Infected Subjects: 48 Weeks Data. HIV Clinical Trials 15:2, pages 51-56.
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Isabel Aldir, Ana Horta & Margarida Serrado. (2014) Single-tablet regimens in HIV: does it really make a difference?. Current Medical Research and Opinion 30:1, pages 89-97.
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Claudia Bernardini & Franco Maggiolo. (2013) Triple-combination rilpivirine, emtricitabine, and tenofovir (Complera™/Eviplera™) in the treatment of HIV infection. Patient Preference and Adherence 7, pages 531-542.
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Giorgio L Colombo, Sergio Di Matteo, Andrea Antinori, Massimo Medaglia, Silvia Murachelli & Giuliano Rizzardini. (2013) Economic evaluation of initial antiretroviral therapy for HIV-infected patients: an update of Italian guidelines. ClinicoEconomics and Outcomes Research 5, pages 489-496.
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Giorgio L Colombo, Sergio Di Matteo & Franco Maggiolo. (2013) Antiretroviral therapy in HIV-infected patients: a proposal to assess the economic value of the single-tablet regimen. ClinicoEconomics and Outcomes Research 5, pages 59-68.
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Giuliano Rizzardini, Paolo Bonfanti, Laura Carenzi, Massimo Coen, Giovanna Orlando, Sergio Di Matteo & Giorgio L Colombo. (2012) Cost-effectiveness analysis of HIV treatment in the clinical practice of a public hospital in northern Italy. Therapeutics and Clinical Risk Management 8, pages 377-384.
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Gaetana Sterrantino, Lucia Santoro, Dario Bartolozzi, Michele Trotta & Mauro Zaccarelli. (2012) Self-reported adherence supports patient preference for the single tablet regimen (STR) in the current cART era. Patient Preference and Adherence 6, pages 427-433.
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Rik Schrijvers & Zeger Debyser. (2012) Combinational therapies for HIV: a focus on EVG/COBI/FTC/TDF. Expert Opinion on Pharmacotherapy 13:13, pages 1969-1983.
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Raffaella Rosso, Antonio Di Biagio, Franco Maggiolo, Loredana Nulvesu, Anna Paola Callegaro, Lucia Taramasso, Bianca Bruzzone & Claudio Viscoli. (2012) Patient-reported outcomes and low-level residual HIV-RNA in adolescents perinatally infected with HIV-1 after switching to one-pill fixed-dose regimen. AIDS Care 24:1, pages 54-58.
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Jean B Nachega, Bernd Rosenkranz & Paul A Pham. (2011) Twice-daily versus once-daily antiretroviral therapy and coformulation strategies in HIV-infected adults: benefits, risks, or burden?. Patient Preference and Adherence 5, pages 645-651.
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Jean B Nachega, Michael J Mugavero, Michele Zeier, Marco Vitória & Joel E Gallant. (2011) Treatment simplification in HIV-infected adults as a strategy to prevent toxicity, improve adherence, quality of life and decrease healthcare costs. Patient Preference and Adherence 5, pages 357-367.
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Giorgio L Colombo, Vincenzo Colangeli, Antonio Di Biagio, Sergio Di Matteo, Claudio Viscoli & Pierluigi Viale. (2011) Cost-effectiveness analysis of initial HIV treatment under Italian guidelines. ClinicoEconomics and Outcomes Research 3, pages 197-205.
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