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Original Research

Peroxisome proliferator-activated receptor gamma-2 P12A polymorphism and risk of acute myocardial infarction, coronary heart disease and ischemic stroke: A case-cohort study and meta-analyses

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Pages 427-436 | Published online: 11 Apr 2008

Keep up to date with the latest research on this topic with citation updates for this article.

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Jyot Amrita, Mridula Mahajan, A.J.S. Bhanwer, Gurinder Mohan & Kawaljit Matharoo. (2017) Peroxisome Proliferator Activated Receptor Gamma (PPARγ) Pro12Ala Gene Polymorphism and Oxidative Stress in Menopausal Women with Cardiovascular Disease from North Indian Population of Punjab. International Journal of Human Genetics 17:1, pages 15-25.
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Caroline Jane Magri, Noel Gatt, Robert G Xuereb & Stephen Fava. (2011) Peroxisome proliferator-activated receptor-γ and the endothelium: implications in cardiovascular disease. Expert Review of Cardiovascular Therapy 9:10, pages 1279-1294.
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Articles from other publishers (19)

Reham M. El-Farahaty, Osama Fouda, Amany EL-Deasty, Abdel-Hady El-Gilany & Narmin Saied. (2022) Peroxisome proliferator-activated receptor γ Pro12 ala polymorphism and risk of cerebral stroke in type 2 diabetes mellitus egyptian patients. Journal of Diabetes & Metabolic Disorders.
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Shujin Li, Chuan He, Haiyan Nie, Qianyin Pang, Ruixia Wang, Zhifu Zeng & Yongyan Song. (2022) G Allele of the rs1801282 Polymorphism in PPARγ Gene Confers an Increased Risk of Obesity and Hypercholesterolemia, While T Allele of the rs3856806 Polymorphism Displays a Protective Role Against Dyslipidemia: A Systematic Review and Meta-Analysis. Frontiers in Endocrinology 13.
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Yongyan Song, Shujin Li & Chuan He. (2022) PPARγ Gene Polymorphisms, Metabolic Disorders, and Coronary Artery Disease. Frontiers in Cardiovascular Medicine 9.
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Fan Cheng, Xiao‐Min Si, Gong‐Li Yang & Lan Zhou. (2021) Relationship between PPAR‐γ gene polymorphisms and ischemic stroke risk: A meta‐analysis. Brain and Behavior 11:12.
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Kay-Dietrich Wagner & Nicole Wagner. (2020) PPARs and Myocardial Infarction. International Journal of Molecular Sciences 21:24, pages 9436.
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Yeqing Tong, Li Cai, Zhihong Wang, Yanwei Zhang, Xuhua Guan, F. Zhan, Jiafa Liu & Qing Lu. (2018) Association Between PPARs Gene Functional Polymorphisms and Ischemic Stroke in Chinese Uyghur Population. The journal of nutrition, health & aging 23:2, pages 175-180.
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Bradford B. Worrall, Nicole A. Chiota-McCollum & Andrew M. Southerland. 2017. Stroke Genetics. Stroke Genetics 219 245 .
Yufeng Qian, Peiwei Li, Jinjie Zhang, Yu Shi, Kun Chen, Jun Yang, Yihua Wu & Xianhua Ye. (2016) Association between peroxisome proliferator-activated receptor-alpha, delta, and gamma polymorphisms and risk of coronary heart disease. Medicine 95:32, pages e4299.
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Peijian Wang, Qiulin Wang, Yanwei Yin, Zhen Yang, Wenzhang Li, Dengpan Liang & Peng Zhou. (2015) Association between Peroxisome Proliferator-activated Receptor Gamma Gene Polymorphisms and Atherosclerotic Diseases: A Meta-analysis of Case-control Studies. Journal of Atherosclerosis and Thrombosis 22:9, pages 912-925.
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Wenjun Xu, Jiahong Xu, Bing Sun, Haibin Chen, Yiping Wang, Feifei Huang, Peng Xi & Jinfa Jiang. (2012) The effect of PPARG gene polymorphisms on the risk of coronary heart disease: a meta-analysis. Molecular Biology Reports 40:2, pages 875-884.
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Yaroslav Winter, Roman Sankowski & Tobias Back. 2013. Obesity. Obesity 29 48 .
Zhijun Wu, Yuqing Lou, Wei Jin, Yan Liu, Lin Lu & Guoping Lu. (2012) The Pro12Ala Polymorphism in the Peroxisome Proliferator-Activated Receptor Gamma-2 Gene (PPARγ2) Is Associated with Increased Risk of Coronary Artery Disease: A Meta-Analysis. PLoS ONE 7:12, pages e53105.
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Yujun Wang & Chibo Liu. (2012) Quantitative evaluation of common polymorphism (rs1801282) in the PPARγ2 gene and hypertension susceptibility. Gene 502:2, pages 159-162.
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L.P. Wang, L.R. Zhao, H.W. Cui, M.R. Yan, L. Yang & X.L. Su. (2012) Association between PPARγ2 Pro12Ala polymorphism and myocardial infarction and obesity in Han Chinese in Hohhot, China. Genetics and Molecular Research 11:3, pages 2929-2938.
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Hulya Yilmaz-Aydogan, Ozlem Kurnaz, Ozlem Kurt, Basak Akadam-Teker, Ozlem Kucukhuseyin, Atike Tekeli & Turgay Isbir. (2011) Effects of the PPARG P12A and C161T gene variants on serum lipids in coronary heart disease patients with and without Type 2 diabetes. Molecular and Cellular Biochemistry 358:1-2, pages 355-363.
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Yaroslav Winter, Tobias Back, André Scherag, Jakob Linseisen, Sabine Rohrmann, Oliver Lanczik, Anke Hinney, Susann Scherag, Michael Neumaier, Peter A. Ringleb, Richard Dodel & Johannes Hebebrand. (2011) Evaluation of the Obesity Genes <i>FTO</i> and <i>MC4R</i> and the Type 2 Diabetes Mellitus Gene <i>TCF7L2</i> for Contribution to Stroke Risk: The Mannheim-Heidelberg Stroke Study. Obesity Facts 4:4, pages 5-5.
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Ulla Vogel, Stine Segel, Claus Dethlefsen, Anne Tjønneland, Anne Thoustrup Saber, Håkan Wallin, Majken K Jensen, Erik B Schmidt, Paal Skytt Andersen & Kim Overvad. (2009) PPARγ Pro12Ala polymorphism and risk of acute coronary syndrome in a prospective study of Danes. BMC Medical Genetics 10:1.
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Fang-I HsiehWei-Cheng LoHuey-Juan LinYi-Chen HsiehLi-Ming LienChyi-Huey BaiHung-Pin TsengHung-Yi Chiou. (2009) Significant Synergistic Effect of Peroxisome Proliferator–Activated Receptor γ C-2821T and Diabetes on the Risk of Ischemic Stroke. Diabetes Care 32:11, pages 2033-2035.
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L. Evangelisti, M. Attanasio, L. Lucarini, F. Sofi, R. Marcucci, C. Giglioli, S. Valente, GF. Gensini, R. Abbate & G. Pepe. (2009) PPARgamma Promoter Polymorphisms and Acute Coronary Syndrome. Atherosclerosis 205:1, pages 186-191.
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