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Review

Renin inhibition with aliskiren in hypertension: focus on aliskiren/hydrochlorothiazide combination therapy

Pages 1205-1220 | Published online: 05 Dec 2008

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (3)

Benjamin J Epstein, Paul T Leonard & Niren K Shah. (2012) The evolving landscape of RAAS inhibition: from ACE inhibitors to ARBs, to DRIs and beyond. Expert Review of Cardiovascular Therapy 10:6, pages 713-725.
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E Van der Merwe & A Carboni. (2011) Strategies to improve blood pressure control and cardiovascular outcomes in hypertensive patients. South African Family Practice 53:6, pages 525-532.
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Konstantinos Savvatis, Dirk Westermann, Heinz-Peter Schultheiss & Carsten Tschöpe. (2010) First-line treatment of hypertension: critical appraisal of potential role of aliskiren and hydrochlorothiazide in a fixed combination. Integrated Blood Pressure Control 3, pages 163-170.
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Articles from other publishers (10)

Georgi Abraham, A Almeida, Kumar Gaurav, Mohammed Yunus Khan, Usha Rani Patted & Maithrayie Kumaresan. (2022) Reno protective role of amlodipine in patients with hypertensive chronic kidney disease. World Journal of Nephrology 11:3, pages 86-95.
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Chrishan S. Samuel & Robert G. Bennett. (2022) Relaxin as an anti-fibrotic treatment: Perspectives, challenges and future directions. Biochemical Pharmacology 197, pages 114884.
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Qiyuan Zhao, Jiantong Shen, Jingya Lu, Fan Li, Qi Jiang & Yuanyuan Wang. (2020) Clinical efficacy, safety and tolerability of aliskiren monotherapy: a protocol for an umbrella review. BMJ Open 10:1, pages e033448.
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Qinghai Meng, Yao Guo, Dini Zhang, Qichun Zhang, Yu Li & Huimin Bian. (2020) Tongsaimai reverses the hypertension and left ventricular remolding caused by abdominal aortic constriction in rats. Journal of Ethnopharmacology 246, pages 112154.
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Ying-Ying Zhang, Ying Yu & Chen Yu. 2019. Renal Fibrosis: Mechanisms and Therapies. Renal Fibrosis: Mechanisms and Therapies 671 691 .
Gregory C. Adam, Juncai Meng, Joseph M. Rizzo, Adam Amoss, Jeffrey W. Lusen, Amita Patel, Daniel Riley, Rachel Hunt, Paul Zuck, Eric N. Johnson, Victor N. Uebele & Jeffrey D. Hermes. (2015) Use of High-Throughput Mass Spectrometry to Reduce False Positives in Protease uHTS Screens. SLAS Discovery 20:2, pages 212-222.
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Wen Zhang, Yi Han, Guoliang Meng, Wenli Bai, Liping Xie, Hui Lu, Yongfeng Shao, Lei Wei, Shiyang Pan, Suming Zhou, Qi Chen, Albert Ferro & Yong Ji. (2014) Direct Renin Inhibition With Aliskiren Protects Against Myocardial Ischemia/Reperfusion Injury by Activating Nitric Oxide Synthase Signaling in Spontaneously Hypertensive Rats. Journal of the American Heart Association 3:1.
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Natalia Andrushko & Vasyl Andrushko. 2013. Stereoselective Synthesis of Drugs and Natural Products. Stereoselective Synthesis of Drugs and Natural Products 1 50 .
Marcin Drag & Guy S. Salvesen. (2010) Emerging principles in protease-based drug discovery. Nature Reviews Drug Discovery 9:9, pages 690-701.
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Zafar H Israili, Manuel Velasco & Valmore Bermúdez. (2010) Direct Renin Inhibitors as Antihypertensive Agents. American Journal of Therapeutics 17:3, pages 237-254.
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